Haliaeetus leucocephalus (bald eagle): 104833651 Help Entry 104833651         CDS       T08630                                  Symbol TSC2 Name (RefSeq) tuberin isoform X1   KO K07207   tuberous sclerosis 2 Organism hle  Haliaeetus leucocephalus (bald eagle) Pathway hle04115   p53 signaling pathway hle04140   Autophagy - animal hle04150   mTOR signaling pathway hle04218   Cellular senescence hle04910   Insulin signaling pathway hle05168   Herpes simplex virus 1 infection Brite KEGG Orthology (KO) [BR:hle00001]  09130 Environmental Information Processing   09132 Signal transduction    04150 mTOR signaling pathway     104833651 (TSC2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     104833651 (TSC2)   09143 Cell growth and death    04115 p53 signaling pathway     104833651 (TSC2)    04218 Cellular senescence     104833651 (TSC2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     104833651 (TSC2)  09160 Human Diseases   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     104833651 (TSC2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:hle01009]     104833651 (TSC2) Protein phosphatases and associated proteins [BR:hle01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      104833651 (TSC2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 RHG29_45_N Motif Other DBs NCBI-GeneID:  104833651 NCBI-ProteinID:  XP_010568771 LinkDB All DBs Position Unknown AA seq 1868 aa AA seqDB search MAVTGVFLLKDSPWASLNGNPVLYLQGLSAACLSAMAKPQSKDSGLKEKFRNLLGLGTSR GSSKSSEGKQTEFIITAEILKELSIECGLSNRIRAISQICEVAKTKKIEEHAVEAIWKVV ADMLQPERPVEARHAVLHLLKSIVQGQGERLGILRAHFFKVIKDYPSNEDLHERLEVFKA LTENGRYITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLEDYVADMVHKICLL CIQTSSSVDIEISLQVLDAVVCYNCLPSENLPVFIITLCRTINVKELCEPCWKLMRNLLG THLGHSAIYNMCRIMEDRAYMADAALLRGAVFFVGMALWGAHRLNSLKNSPTSVLPSFLK AMTCPNAVVSYEIVLSITRLIKKYGKELQAVTWDILLDIMERLLQQLQSLESQELKSIVH DLLTTVEELCDQNEFHGSEERFFELVERCADQRPESSVLNLITYRAQSIHPAKDGWIHNL QMLMERFFRNESRSAVRIKVLDVLSFVLSINRQFYEEELINLVVISQLAHIPEDKDHQVR KLATQLLVDLAEGCNTHHFNSLLDIIEKVAAHSLSSPSELEERDLLSYSASLEDVKTAVL GLLIILQTKLYSLPSSHAMRVYEMLIHHVQRHYIYAYSLAVASSIRLQVFDFLLMLRADS LHRLGLSNKDGAVRFSPYCLCDFVEAEKRASEKKPTGTLSPPSGSPSVPSQNATVRIGHL PYSMVFGVLLQCLKQETDWKVLKLVLNKLPESLRYKVLFLTSPCNIDLLASALSYMLTDK KTTDRLHGTPEGFSRTDLHLAVVPVLTALISYHNYLDKAKQREIVYCLEHGLIYRCANQC VVALSVCSVEMPDIIIKALPVLIVKLTHISATANMAIPLLEFLSTLARLPHLYRNFAAEQ YASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPYITKGLRSNVLLSF DDTPEKDSFRARSTSLNERPKSSLRLAKNAKQGLNNSPPVKELKESSAVDAFRSRSISVS EHVVRSRIQTSITSSSLGSADENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPK RSPVGEFLLAGGRTKTWLVGNKLVTITTSVGTGTRSLLGLDSGDLQSSTESSSDPVLQVR QTKEAPAKLESQAGQQVCRSSRNRVRSMSGGHALRVGALDSSASHFPSGSASQGTQGPPA PASRSEKTNPAPQTPLQKEKANLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFS SDINNMPLQELSNALMAAERFKEHRETALYKSLSVPSSSLATGTAKPSLLQRSNTVASFS SMYQSSCQGKLHRSISWAESAVVLEEGTPLEMELKETESPAGSPESEDIETSCSEQVLSE ERFGKPQESYSRSSSTSSQEEKSLKSEDLVEGGIPIGRVLPSEDGRTLEELSFQPSQPLS KSSSSPELQTLQEVLKDANGREVTRRLSTEVKSKSQSGNLEGEGLGSWLGKGEDARVTGS GGLDGTSPVTSPRSPSGHRPRGYTISDSAPSRRGKRIERDAFKSRTAASNAEKVPGINPS FVFLQLYHSPFFGDENNKPLLLPNETFERSVQLLDQIPSYDTHKIAVLYVGEGQSNNEIA ILSNEHGSYRYTEFLTGLGKLIELKDCQPDKIYLGGLDVCGEDGQFTYCWHDDIMQAIFH IATLMPTKDLDKYRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYDC NLVTLQCRKDMEGLVDTSVAKIISDKNLPFVARQMALHANMASQVHHSRSNPTDTYPSKW IARLRHIKRLRHRLREETQYQTPGLPLQMHPSAPTKPPPQIPQDPPPTYETGQRKRLISS VDDFTEFV NT seq 5607 nt NT seq  +upstreamnt  +downstreamnt atggctgttactggtgttttcctgcttaaagattccccttgggcctcccttaatggaaac cctgttctgtatttgcaggggctcagtgctgcttgcttgtcagcaatggcaaagcctcag agcaaggattctggactgaaggagaagttcaggaatctcctggggctgggaacatcccgg ggaagctcaaagtcatcagagggcaagcaaacggagtttatcatcactgcggaaatactc aaggaactgagcatagaatgtggattaagtaataggatacgagcaatcagtcaaatttgt gaagtggcaaagacaaaaaaaattgaggagcatgcagtggaagcaatatggaaagtggta gctgatatgctccagccagagcgccctgtggaagccagacatgctgttcttcatctgcta aagtcaatcgttcaaggacagggtgagagattagggatcctcagagcacatttttttaag gttattaaggactatccttccaacgaagacttgcatgaacggcttgaagtgttcaaggct ctaacagagaatggacgatatatcacctacttagaagaagagttagctgactttgtacta cagtggatggatgttggtttgtcttctgagttccttctggttttagtgaacctggtgaaa ttcaatagctgctatctggaagactatgtagctgacatggtccacaagatatgcctcttg tgcattcagacttcctcatctgtggacatagagatttccttgcaagtcctagatgcagtt gtttgctataattgtctgccatcagagaacctgccagtatttatcatcactttgtgccgt accatcaatgtgaaggagctctgtgagccgtgctggaagcttatgcgcaaccttttggga actcatttgggacacagtgccatctacaacatgtgcaggatcatggaagacagagcttac atggcggatgcagcgctgctgagaggagctgtgttctttgttgggatggctctgtggggt gctcatcgcctcaattcactcaagaattccccaacttcagtgctgccttcattcctcaag gccatgacatgtcccaatgcagttgtgtcttacgagatagttctgtccataacacgtcta ataaagaagtatggaaaggagctgcaagctgtaacgtgggatatccttttggacatcatg gagcgattactgcaacagctgcagagtctggagagccaagaacttaagtccattgtacat gatcttttgactacggtagaagaactctgtgaccagaatgaattccatggctctgaagag agattttttgagctggtggaaagatgtgctgatcagagacctgaatcttctgtattaaac ttgataacatacagagctcaatccattcatcctgccaaagatggctggattcacaacctg cagatgttaatggagagattcttcaggaacgaaagtcgtagtgctgttcgtattaaagtt ctggatgtcttgtcctttgtcctgagtattaacagacagttctatgaggaagagctgata aacttggttgtgatctctcagctggctcacattccagaggataaagaccatcaagtccga aaactggccactcagctactcgtagacctggctgaaggctgcaacacacatcactttaac agcttgcttgatatcatagaaaaggtagctgcacattctctctcatctccttctgaactg gaagagagggacttgctatcgtattcggcttccttggaggatgtcaagacagcagttctt ggactcttgataattcttcagacaaaactctacagcttaccctccagccatgcaatgcgg gtgtatgagatgcttattcaccacgtccaacgccattatatatatgcgtacagccttgct gttgctagcagcatcagattgcaggtgtttgatttcctactgatgcttcgagctgactcc ctccaccgtcttggcctttccaacaaagatggagcagtgaggttcagcccttactgtcta tgtgattttgtagaagcagagaagagggcttctgagaaaaagcccactggtacgctctct ccgccttcaggaagtcccagtgtgccttcccagaatgccactgttcggatagggcatctg ccatattcaatggtctttggtgtccttctgcagtgtttgaagcaagagacagactggaag gtgttgaagttggtcctcaataaattacctgaatccctccgctataaagtgctattttta acctctccttgtaacatagacctcctggcctccgcactgagctacatgctcacagacaaa aagactactgacaggctccatggtaccccggaaggcttttctcgcactgatttgcatctg gctgtagtcccagtactgacggcattaatatcttaccataattacctggacaaagctaaa cagcgtgaaatagtgtattgcctggaacatggtcttatttatcgctgtgcaaaccagtgc gttgtggcactctctgtctgtagtgttgagatgcctgacatcatcataaaggcacttcct gtcttaatagtcaaattaacccacatttctgctacagccaatatggcaatccctctctta gaatttctttcaactctagcgaggctgcctcacctctacaggaactttgcagcagagcag tatgccagtgtgttcgccatctccctgccatacacaaacccttccaagtttaaccagtac atcgtttgcctggcccatcatgtgatagctatgtggttcattcggtgtcgccttcccttc cgaaaggactttgtcccctatattacaaagggtttgcgctcgaatgtcctcctttccttt gatgacacgcctgagaaggacagtttcagggctcgcagtacaagcctgaatgagaggcca aaaagtagtttaagactagccaaaaatgcaaagcaaggcttgaataactctcctccagtg aaagagctgaaagaatcctctgcagttgatgccttccgatcccgcagcatcagtgtgtct gaacatgtggtccgcagtcggatacaaacatccatcactagttcaagcctgggctctgca gatgaaaattcaatggctcaggctgatgacaacttaaaaaatctccacctggaactcacc gagacctgtctggatatgatggctcgatacgtcttttcaaacttcactgccgtgcctaag aggtctcctgtgggtgagtttctgttagctggaggaaggacaaagacgtggctggttggt aacaagctggtgaccatcactacaagtgttggaacagggacaaggtccttgcttggccta gactctggagacctccaaagcagcacagaatcaagctcagaccctgttttgcaagtgaga caaactaaagaagctccagcaaaactggaatctcaagctgggcagcaggtttgcagaagc tctcgcaacagagtccgatccatgtctggtggtcatgccttacgtgttggtgccttagac agctcagcctcccattttcccagtggctcagcttcccaagggacacagggtcctcctgct ccagcatctcgatcagagaagactaatcctgctccacagacacctctgcagaaagaaaaa gcaaacttagctgcgtatgttccactgctgacacagggatgggcagaaatcctggtgcgc agacccacaggtaacacaagctggctaatgagtctggagaacccgctcagtccattttct tcggatattaataatatgcccctgcaagagctctctaatgcactcatggctgcagagcgt tttaaagaacacagagaaacggctctgtataaatccctctctgtcccctcctccagcttg gccaccggcacagccaaaccatcacttctccagcgttccaacacagtggcctctttctct tccatgtaccagtccagttgtcaagggaagttgcacaggagcatatcctgggcagaatca gcggtggtgctggaggaagggaccccgttggaaatggagctaaaggaaactgagtcccca gctgggtctccagagagtgaagacattgagacttcatgttctgaacaagtcctgagcgag gaaaggtttggtaaaccccaggagtcttatagcaggtcctcctcaacctccagccaagaa gaaaaatctctgaagtcggaagacctggtggagggtggaattcccattgggagagtcctc ccatcagaggatggccgaacactggaggagctttccttccagccatcccagccgctcagc aagtcgagttcttctcccgagctacagacactgcaggaggtcctcaaagatgcaaacggc agagaagtaacaaggaggctgagcacagaagtgaaatcaaaatcccagtctgggaacctg gaaggggaagggctgggcagttggctgggcaagggggaggatgccagagtgactgggtca ggcgggttggatggcaccagtcctgtcacctcgcctcgctctccctctgggcaccggccc cggggatacactatctctgactcagccccatcaaggaggggaaaaaggattgaaagagat gccttcaaaagcagaacagcagcctccaatgctgagaaagtacccggaataaacccaagc tttgtgtttttacagttgtaccactccccattctttggcgatgaaaacaacaagcccctt ttgttgccaaatgagacgtttgaaagatcagtgcagctcctggatcaaattccttcttac gacacacacaagattgcagtgctctatgttggagaaggccagagcaacaacgaaatcgca attctgtcaaatgagcatggatcctaccgctatacagagttcctgactgggttagggaag ctcattgagctcaaagactgtcagccagataaaatctaccttggtggcctggatgtgtgt ggggaggatggacagtttacctactgttggcatgatgacattatgcaagccattttccac attgctactctgatgcccacaaaggatttggataaatatcgctgtgacaagaaaaggcac cttgggaatgattttgtttctatcgtttacaatgattctggagaagactttaaactggga acaataaagggtcagttcaattttgtgcacgttatcatcacaccacttgactatgactgt aacctggtgacgctgcagtgtcggaaagacatggagggtctcgtagacacgagtgtcgct aagatcatctctgataagaacctgccatttgtagcccgtcagatggccttgcatgctaac atggcttcccaggttcatcacagtcgatcaaaccctactgacacctacccatccaaatgg attgcaaggctacgtcatatcaagagactaaggcaccggctgcgtgaagaaacccagtac cagactcctggccttcccctgcagatgcatccatctgctccgacaaagccccctccccag atccctcaggaccctccacccacctatgagactggacagaggaagcggctgatctcctca gtggatgacttcacagagtttgtgtag

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