Haliaeetus leucocephalus (bald eagle): 104836308
Help
Entry
104836308 CDS
T08630
Symbol
PLCB4
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1
KO
K05858
phosphatidylinositol phospholipase C, beta [EC:
3.1.4.11
]
Organism
hle
Haliaeetus leucocephalus (bald eagle)
Pathway
hle00562
Inositol phosphate metabolism
hle01100
Metabolic pathways
hle04020
Calcium signaling pathway
hle04070
Phosphatidylinositol signaling system
hle04081
Hormone signaling
hle04082
Neuroactive ligand signaling
hle04261
Adrenergic signaling in cardiomyocytes
hle04270
Vascular smooth muscle contraction
hle04310
Wnt signaling pathway
hle04371
Apelin signaling pathway
hle04540
Gap junction
hle04621
NOD-like receptor signaling pathway
hle04912
GnRH signaling pathway
hle04916
Melanogenesis
Module
hle_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
hle00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
104836308 (PLCB4)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
104836308 (PLCB4)
04371 Apelin signaling pathway
104836308 (PLCB4)
04020 Calcium signaling pathway
104836308 (PLCB4)
04070 Phosphatidylinositol signaling system
104836308 (PLCB4)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
104836308 (PLCB4)
04081 Hormone signaling
104836308 (PLCB4)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction
104836308 (PLCB4)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
104836308 (PLCB4)
09152 Endocrine system
04912 GnRH signaling pathway
104836308 (PLCB4)
04916 Melanogenesis
104836308 (PLCB4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
104836308 (PLCB4)
04270 Vascular smooth muscle contraction
104836308 (PLCB4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hle04131
]
104836308 (PLCB4)
Enzymes [BR:
hle01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
104836308 (PLCB4)
Membrane trafficking [BR:
hle04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
104836308 (PLCB4)
Endocytosis
Macropinocytosis
Phospholipase C
104836308 (PLCB4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PH_14
PI-PLC-Y
PLCB1-4-like_EFh
EF-hand_like
C2
PLC-beta_C
EF-hand_7
EF-hand_6
Motif
Other DBs
NCBI-GeneID:
104836308
NCBI-ProteinID:
XP_010573115
LinkDB
All DBs
Position
Unknown
AA seq
1206 aa
AA seq
DB search
MAKPYEFNWQKPVPSFMQDGAVFDRYEEESFVFESNCLFQVDEFGFFLSWRSEGKEGQVL
ECSLINSVRFGAVPKDPKILSALEAVGKSESELEGRIVCVCSGTDLVNISFTFMVAENTE
IAKQWVEGLGSIIHNFRANNVSPMTCLKKHWMKLAFLTNTNGKIPVRSITRTFASGKTEK
VIFQALKELGLPSGKNDEIEPAAFTYEKFYELTQKICPRTDIEDLFKKINGDKTDYLTVD
QLVSFLNEHQRDPRLNEILFPFYDTKRAMQIIETYEPDEDLKSKGVISSDGFCRYLMSDE
NAPVFLDRLELYQEMDHPLAHYFISSSHNTYLTGRQFGGKSSVEMYRQVLLAGCRCVELD
CWDGKGEDQEPIITHGKAMCTDILFKDVIQAIKETAFVTSEYPVILSFENHCSKYQQYKM
SKYCEDLFGDLLLKQPLETHPLDPGKALPSPNDLRRKILIKNKRLKPEVEKKQLDALKKM
MEAGETSAPVNILEDDNEEEIESADQEEEAHPEYKFGSDLTVDDYSQKEAVAISVKKAVE
DSEQENNKKGLVTVEDEQAWMASYKYVGATTNIHPYLSTMVNYAQPVKFQGFDVAEERNI
HHNMSSFNESVGLGYLKTHAIEFVNYNKRQMSRIYPKGGRVDSSNYMPQIFWNAGCQMVS
LNYQTPDLAMQLNQGKFEYNGSCGYLLKPDFMRRPDRTFDPFSETPVDGVIAATCSVQVI
SGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNEESFVFRKVILPDLA
VLRIAVYDDNNKLIGQRILPLDGLQAGYRHISLRNEGNKPLSLPTVFCNIVLKTYVPDGF
GDIVDALSDPKKFLSITEKRADQMRAMGIETSDIADVPNDTSKNDRKGKANNAKANVTPQ
SSSELRPSTTAGFGSGTDAKKGIDLIPQVKIEDLKQMKAYIKHLKKQQKELSALKKKHAK
EHSAMQKLHCTQIDKIVAQYDKEKVSYEKMLEKAIKKKGGSNCLELKKETEIKIQALTSD
HKSKVKEIVAQHTKEWSEMINTHSAEEQEIRDLHLNQQCELLKKLLINAHEQQTQQLKFS
HDRESKEMRANQAKISMENSKAISQDKSIKNKAERERRVRELNSSNTKKFLEERKRLAMK
QSKEMDQLKKVQLEHLEVLEKQNEQLLKSCHAVSQTQGKGDAADGEAGSRDGSQASNSGL
KPQQAN
NT seq
3621 nt
NT seq
+upstream
nt +downstream
nt
atggcaaaaccttacgaatttaactggcagaagccagttccctcttttatgcaagatgga
gctgtgtttgatagatatgaagaggaatcttttgtctttgaaagcaactgtctcttccaa
gtggatgaatttggcttttttctgagctggagaagtgaaggaaaggaaggacaggtatta
gaatgctccctgatcaacagtgttcgttttggagctgtaccaaaggatcccaaaatactg
tctgcacttgaggctgttggaaaatcagaaagtgagttggaaggacggatagtgtgtgtt
tgcagtggcacagatctggtgaacatcagcttcactttcatggtagcggaaaatacagaa
atagccaagcaatgggtagaaggacttggatccatcatacataactttagagctaacaat
gtcagtccaatgacatgtctcaagaaacactggatgaaactggcctttctaacaaacaca
aatgggaaaattccagttcggagcattaccagaacctttgcatcaggtaaaacagaaaaa
gtgatctttcaggcacttaaggaattaggtcttcccagtggaaagaatgatgaaattgag
cctgcagcgtttacttacgagaaattttatgagctcacccaaaagatatgtccccgaacg
gacatagaggacctctttaagaagatcaatggagacaaaactgattatttaacggtagac
caattagtgagctttctaaatgaacatcaacgagatcctcggctcaatgaaattttattt
cccttttatgacacaaaaagagcaatgcagataattgagacatatgagccagatgaagac
ttgaagagtaaaggtgtcatatcaagtgatgggttttgcagatacttgatgtcagatgaa
aatgccccagttttcctagatcgtctggaattatatcaagaaatggaccatcctttggct
cattatttcatcagctcctctcacaatacatatttaacaggcaggcagtttggtggcaag
tcttcggtggagatgtacagacaagtgcttttggctggatgcaggtgtgttgagctggac
tgttgggatggcaaaggtgaagaccaagaaccaataataacgcatggaaaagcaatgtgt
acagacattcttttcaaggatgtaattcaagccattaaggaaacagcatttgttacatca
gagtatcctgtcattctttcatttgaaaatcactgcagcaaatatcaacagtataagatg
tcaaaatactgtgaagatctttttggagatctcctgttgaagcagcctctagaaacacat
ccacttgatccaggtaaagccttaccttcacctaatgacctcagaagaaagattctcata
aagaataaaaggttgaaacctgaggtagaaaaaaaacagcttgatgctctgaaaaagatg
atggaggctggggaaacttctgctcctgtaaatatcctagaggatgataatgaagaagaa
atagaaagtgctgaccaggaagaagaagctcatccagagtacaaatttggaagtgacctt
actgtagatgattacagtcaaaaagaagctgttgccatcagtgtcaaaaaggctgttgaa
gattctgagcaagaaaacaataaaaagggtttagtaactgttgaagatgaacaagcgtgg
atggcatcttacaaatatgtaggtgccacaaccaatatacatccatatttatcaacaatg
gtcaactatgctcaacctgtaaaatttcaaggtttcgatgtagcagaagaacgtaatatt
catcataatatgtcctctttcaatgaatcagttggactaggatatttgaagacccatgcc
attgagttcgtgaattataataaacgacaaatgagtcggatatacccaaagggaggccga
gtggattccagtaattacatgcctcaaattttctggaacgctggctgccagatggtctca
ctgaactatcagaccccagatttagcaatgcagttgaatcaaggaaaatttgaatataat
ggatcatgcgggtatctacttaaaccagatttcatgcgacgaccagatcgaacatttgac
cctttctctgaaactcctgtagatggtgtaatcgctgcaacgtgttctgtgcaggtaata
tctggtcagttcttatcagacaaaaaaattggtacgtatgtagaagtggatatgtatggt
ttacccacggatacgatacgtaaagaatttcgaacacgcatggtgatgaacaatggtctg
aaccctgtttacaatgaagaatcatttgtatttcgaaaggttattctccctgatcttgct
gtcctgagaatagcagtgtatgatgacaataataagttgattggtcagaggatcctgcct
ctggatggtctgcaagcaggttacagacacatttcccttcggaatgagggcaacaaacca
ctctctcttccaacggttttctgcaacattgtgcttaaaacatatgtgcctgatggtttt
ggagatattgtggatgctttatcagatccaaagaaatttttgtctatcacagaaaaaaga
gcagaccaaatgagggctatgggtatcgaaactagtgatatagccgatgtaccaaatgac
acttcaaagaatgatagaaaaggaaaagccaataatgcgaaagccaatgtaacacctcag
agtagctctgaacttcgaccaagtaccaccgcaggctttggatctgggactgatgctaag
aaaggtatagaccttattcctcaagtgaagatagaagatttaaagcaaatgaaggcttat
ataaagcatttaaagaagcagcagaaagagctgagtgccttaaagaagaaacatgcaaag
gagcacagcgctatgcagaagttgcactgcacacaaattgacaaaatagtggcacaatat
gataaagaaaaggtatcatacgagaaaatgttagagaaggcaatcaagaagaagggagga
agtaattgtcttgaattgaagaaagaaacggaaattaaaattcaggcactaacatcagat
cacaaatctaaggtcaaagagattgtggcacagcacactaaagagtggtctgagatgatc
aatacgcacagtgccgaagagcaagaaatccgtgatttgcacttgaaccaacagtgtgaa
ctactgaagaaactgctgattaatgctcatgaacaacaaacccagcagctaaaattttca
catgacagggaaagcaaggaaatgcgtgccaaccaggctaaaatatctatggaaaacagc
aaagccataagccaagacaaatctatcaaaaataaagctgaaagagagaggcgagtcaga
gaactgaacagcagcaacacaaaaaagttcctggaagaaagaaaaaggctggcaatgaag
cagtcaaaagaaatggatcagttgaaaaaagttcaacttgagcatttagaagtcttggag
aagcagaatgagcagcttttgaaatcctgtcatgcagtgtctcaaacacaaggcaaagga
gatgcagcagatggtgaagctggaagcagagatggatcgcaggccagcaacagtggtcta
aagcctcagcaagcaaattga
DBGET
integrated database retrieval system
