Haliaeetus leucocephalus (bald eagle): 104843226 Help Entry 104843226         CDS       T08630                                  Symbol JAK2 Name (RefSeq) tyrosine-protein kinase JAK2   KO K04447   Janus kinase 2 [EC:2.7.10.2] Organism hle  Haliaeetus leucocephalus (bald eagle) Pathway hle04081   Hormone signaling hle04148   Efferocytosis hle04217   Necroptosis hle04920   Adipocytokine signaling pathway hle05164   Influenza A hle05168   Herpes simplex virus 1 infection Brite KEGG Orthology (KO) [BR:hle00001]  09130 Environmental Information Processing   09133 Signaling molecules and interaction    04081 Hormone signaling     104843226 (JAK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     104843226 (JAK2)   09143 Cell growth and death    04217 Necroptosis     104843226 (JAK2)  09150 Organismal Systems   09152 Endocrine system    04920 Adipocytokine signaling pathway     104843226 (JAK2)  09160 Human Diseases   09172 Infectious disease: viral    05164 Influenza A     104843226 (JAK2)    05168 Herpes simplex virus 1 infection     104843226 (JAK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:hle01001]     104843226 (JAK2) Enzymes [BR:hle01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      104843226 (JAK2) Protein kinases [BR:hle01001]  Non-receptor tyrosine kinases   JAK family [OT]    104843226 (JAK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 FERM_F1 SH2_1 Jak1_Phl Kdo ABC1 Kinase-like FERM_C_FAK1 RIO1 FERM_M Motif Other DBs NCBI-GeneID:  104843226 NCBI-ProteinID:  XP_010584333 LinkDB All DBs Position Unknown AA seq 1130 aa AA seqDB search MACLTMTNTEGTATSTVHQNGDIHGNTSAPKHTEPLLQVYLYHSPGKTGGDYLQFPAGEY VAEEICTVACKACGIMPVYHNMFALMSETDRMWYPPNHIFHVDEATRLILLYRIRFYFPH WYCNGTSRAYRYGILRGAESPVLDDLVMSYLFAQWRDDFLDGWIQMPVTHETQEECLGMA VLDMMRVAKEKDQTPLAVYNSVSYKMFLPKCVRAKIQDYHILTRKRIRYRFRKFIQQFGQ CKATARNLKLKYLINLETLQSAFYSEVFEVKEPGGDPSGEGSFATIVITGNGGIQCSRGK LKNCETLAEQDLQTYCDFPDIIDVSIKQASQEGSSERRIVTIHKQDSKNLEAEFQSLREA LSFVSLIDGYYRLTADAHHYLCKEVAPPSVLENIQSNCHGPIFMDFAISKLKKAGNQTGF YVLRCSPKDFKKYFLTFAIERENTTDYKHCLITKNENGEYNLSGTKRSFGNLKDLLTCYQ TETVRSDSIIFQFIKCCPPKPKDKSNLLVFRSNSVSDVPSSPTLQRHNNVNQMVFHKIRN EDLIFEESLGQGTFTKIFKGVRKEVGDYGQLHQTEVLLKVLDKVHRNYSESFFEAASMMS QLSYKHLVLNYGVCVCGEENILVQEYVKFGSLDTYLKKNKNVINILWKLEVAKQLALAMH FLEDKGLVHGNVCAKNILLIREEDRKSGNLPFIKLSDPGISITVLPRDILLERIPWVPPE CIENPKQLSLATDKWSFGTTLWEICSGGDKPLSALDSSRKLQFYEDRHQLPAPNWTELAN LINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTESDMLPNMRIGALGFSGAFEDRDPT QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL KSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERLDHKKLLLYASQICK GMEYLGTKRYVHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA PESLTESKFSVASDVWSFGVVLYELFTYIDKSKSPPAEFMRMIGNDKQGQMIVFHLIELL KNNGRLPRPDGCPDEIYAIMKECWNNNVTQRPTFRDLAQRVDHIRDNMGG NT seq 3393 nt NT seq  +upstreamnt  +downstreamnt atggcctgtcttacaatgacaaatacggaaggtacagcaacttctactgtccaccagaat ggtgacatccatgggaataccagtgcacccaagcatacagaaccattgcttcaagtgtac ctttatcattctcctgggaagacaggcggagactaccttcaatttccagctggagaatat gttgcagaggagatttgtactgttgcctgtaaagcctgtggtatcatgccagtgtatcat aacatgtttgcactcatgagtgaaacagacagaatgtggtatcccccaaatcacatcttt catgtagatgaagcaaccagactcatcctgctttaccggataaggttttattttccccac tggtattgcaatggtaccagcagagcatatcggtatggcattcttcgaggtgcagaaagc cctgttcttgatgatcttgtcatgtcttacctatttgcacagtggcgagatgattttttg gatggatggatacagatgcctgttactcatgaaacacaagaagaatgccttggaatggct gttctggatatgatgagggtggccaaagaaaaggaccaaaccccactggctgtttacaat tcagtcagctacaaaatgtttttgcctaaatgcgtgcgagcaaaaatccaagactaccac attttgacgagaaaaagaataaggtacaggttccgcaaatttatacaacagtttggccaa tgcaaagctactgccagaaacttgaaacttaagtatcttataaatctggaaacccttcag tctgccttctattcagaggtttttgaagtaaaagaacctggtggagatccttctggagag ggaagttttgcaaccattgtaataactggaaatggtggaattcagtgctcaagaggaaaa cttaaaaactgtgagacactggcagagcaggatttacaaacatactgtgattttcctgat ataattgatgtcagcattaagcaagcaagccaagaaggctccagtgagagaagaattgtc accattcacaaacaagacagcaagaatctggaggctgaatttcagtcattaagagaagct ctctcctttgtatcattaatcgatggatattacagattaactgcggatgcccaccattat ctctgtaaagaagtagcaccaccatcagtccttgaaaatatccaaagcaactgccatgga cctattttcatggactttgctatcagtaaactgaagaaagcaggtaatcagactggtttc tacgttcttcgttgcagtcctaaagattttaaaaaatacttcctcacctttgctattgag cgtgagaataccactgattataagcactgcttaattacaaagaatgagaatggagaatat aaccttagtggaaccaagagaagttttggtaatcttaaggatctgctgacctgttaccag acagaaaccgtccgttcagacagcataattttccagttcatcaagtgctgtcctccaaaa ccaaaagataaatcaaatctcctagtcttcagaagcaatagtgtttctgatgtaccttca tcacctacgctacagagacacaataatgtcaaccagatggtctttcacaaaatccggaat gaggatttaatatttgaggagagtcttggacagggcacatttactaagattttcaaaggt gtaaggaaggaagtgggagactatggccagctccatcaaactgaagttcttttaaaggtg ctggataaagtgcatagaaactattctgagtccttctttgaggcagcaagtatgatgagc cagctttcttacaaacatttggtgttaaattatggagtctgcgtatgtggagaggaaaac atccttgtacaagaatatgtaaaatttggatccttagacacgtatttgaaaaagaacaaa aatgttatcaatatcttgtggaagctggaagtagccaaacagttggcattagccatgcat tttctggaggataaaggccttgttcatgggaatgtctgtgcaaaaaacatcttgcttatc agagaggaagacaggaagtctggaaaccttccgtttataaaactaagtgatcctggcatc agtattacagttttgccaagagatattcttcttgagagaataccatgggttccacctgaa tgtattgagaatcccaaacaattaagtctggccacagacaaatggagttttggtactact ttgtgggaaatctgcagtggaggagacaaacctctgagtgcattggattcttcaagaaaa ctacagttttatgaagataggcaccagcttcctgcccccaactggacagaactagcaaac cttataaacaactgtatggattatgagccagatttcaggccttcatttagagcaattata cgcgacttgaatagtttgttcactccagattacgagctactgacagaaagtgatatgttg ccaaatatgagaattggagcacttggattttctggcgcttttgaagatcgtgacccaaca caatttgaagaaagacatcttaagtttttacagcaacttggcaagggaaactttggcagt gttgagatgtgccggtatgacccactgcaggataatactggggaggtggtggctgtgaaa aagctgcaacatagcacagaagagcaccttagggactttgaaagagaaatcgaaatactt aaatctctgcagcatgataacattgttaaatacaaaggagtatgctacagcgcaggtcgt aggaatctaaggttaattatggaatacttaccgtatggaagtttacgagattatctgcag aaacacaaggaaaggcttgaccacaagaagcttttgctgtatgcatctcagatatgcaag ggcatggagtatctgggtacaaaaagatacgttcaccgcgatttagcaacaagaaatatc ttagtggagaatgagaacagagttaaaattggagattttggattgacaaaagtcttgcca caagacaaagaatactacaaagtaaaagaacctggtgaaagccctatattttggtatgct ccagaatctctgacagaaagcaaattttctgtggcctcagatgtgtggagttttggtgtg gtcttgtatgaactcttcacgtatattgacaagagcaaaagcccaccagctgaattcatg cgcatgatcggcaatgataaacaagggcagatgattgtatttcatttgatagagcttttg aagaataatggacgactaccaagaccagatggatgccctgatgagatttatgctatcatg aaagaatgctggaacaataatgttacccagcgccccacctttagggatcttgctcagcga gtggatcatataagggacaacatgggtggatga

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