Humulus lupulus (common hop): 133802021
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Entry
133802021 CDS
T11341
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha 2, mitochondrial-like
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
hlp Humulus lupulus (common hop)
Pathway
hlp00280
Valine, leucine and isoleucine degradation
hlp00640
Propanoate metabolism
hlp00785
Lipoic acid metabolism
hlp01100
Metabolic pathways
hlp01110
Biosynthesis of secondary metabolites
hlp01210
2-Oxocarboxylic acid metabolism
Module
hlp_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hlp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
133802021
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
133802021
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
133802021
Enzymes [BR:
hlp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
133802021
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Motif
Pfam:
E1_dh
DXP_synthase_N
GspH
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
133802021
NCBI-ProteinID:
XP_062096239
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Position
1:195218437..195235360
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AA seq
476 aa
AA seq
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MALWTRKSVNVVTHFVSKQGSFKRSSWSHSFHQRRAVPDAYAPNLKNPVVDVVNTPTSFC
RFESTKAEKLSDSFYDFDANQQVLDFPGGKVAFSTELKFFSESPEERVHCYRVLDNDGQI
ISGSTYVQVNKEVALKMYSEMVTLQVMDTIFYEAQRQGRISFYLTTIGEEAINIASAAAL
TPEDLIFPQYREPGVLLWRGFTLQEFANQCFGNKADYGKGRQMPIHYGSNKLNYFTVSSP
ISTQIPQAVGAAYSLKMDRKDACAVTYFGDGGTSEGDFHAALNFAAVREAPVVFICRNNG
WAISTAIEDQFRSDGIVVKGQSYGIRSIRVDGNDALAMYSAVNAARNIAIRENRPVLIEA
LTYRVGHHSTSDDSTKYRSTKEIQWWRLKRDPVTRFRQWIECNGWLDDGAELEHRNSVRK
QMLQAIQVAEKVEKPAIADLFTDVYDVLPSNLVEQKKLLKETVKRYPKEYPSDVPI
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atggctctttggactagaaaatcagtaaatgttgttacccattttgtttcaaagcagggt
tctttcaaacggagttcctggtctcattctttccatcaaagacgtgctgttccagatgca
tatgctccaaatctcaaaaacccagttgtggacgttgttaatacaccaacttctttttgt
cgttttgagtctaccaaagctgagaaactgtcggattcattttatgattttgatgccaat
caacaggtcttggattttccaggaggaaaagttgcattctctactgaattgaaattcttt
tccgaatcccctgaggagagggtacactgctatagggtgcttgacaacgatggacagatt
atttcaggcagcacctatgtacaggtcaataaagaagtagctctaaaaatgtacagtgaa
atggtcacacttcaagtgatggatactatattctatgaagcacaaagacaagggagaatt
tctttttatctaaccacaattggagaagaagcaatcaacattgcatctgcagcagcatta
actcctgaagaccttatttttcctcagtatcgggaaccaggagtgctattatggcgtggt
ttcaccctgcaagaatttgcgaaccagtgctttggtaacaaagctgattatgggaaaggc
aggcaaatgcctatacactatggatctaacaagctcaattacttcacggtatcatcacct
atatctacacaaattcctcaggctgttggtgctgcatattcattaaagatggacagaaaa
gatgcctgcgccgtcacttattttggtgatggcgggacaagtgagggtgactttcatgct
gctttaaacttcgcggcagttagggaggcaccggttgtattcatctgccggaacaatgga
tgggctatcagtacagcaatagaagatcagtttcgaagtgatggcattgttgttaagggt
cagtcatatggaatccgaagtattcgagtagatggtaatgatgctcttgcaatgtacagt
gctgttaatgctgctcgtaacatcgcaattcgtgagaacagaccagtcttaattgaggca
ctaacctatcgagtgggacaccattcaacttctgacgattcaaccaaatatcgatccact
aaagagatccaatggtggagattgaaacgagaccctgtaactcgatttagacaatggata
gaatgtaatggttggttggatgatggggctgaattagagcatagaaacagtgtgagaaaa
cagatgttacaagcgattcaagtggctgagaaggtggaaaagccagcaattgcagacctt
tttacagatgtatatgatgttctaccatccaaccttgttgagcaaaagaagttgctgaag
gaaacagtcaaaagatatccaaaggaatacccgtcagatgttcctatctag
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