Humulus lupulus (common hop): 133802089
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Entry
133802089 CDS
T11341
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha 2, mitochondrial-like isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
hlp Humulus lupulus (common hop)
Pathway
hlp00280
Valine, leucine and isoleucine degradation
hlp00640
Propanoate metabolism
hlp00785
Lipoic acid metabolism
hlp01100
Metabolic pathways
hlp01110
Biosynthesis of secondary metabolites
hlp01210
2-Oxocarboxylic acid metabolism
Module
hlp_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hlp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
133802089
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
133802089
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
133802089
Enzymes [BR:
hlp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
133802089
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Motif
Pfam:
E1_dh
TPP_enzyme_C
GspH
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
133802089
NCBI-ProteinID:
XP_062096323
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Position
1:195595214..195599090
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AA seq
487 aa
AA seq
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MALWTRKSINAVSHLVSKLGFLGVINRSSWSHSFHQRHPISDACAPNLKNPVVDIVNTPT
HFAFSRFESTKAEKQSDSFHNFDANRQVFIVQQVLDFPGGEVAFSPELKFISESPEGRVH
CYRVLDNKGQIISGSTYAQVNKEVALKMYSEMVTLQVMDTIFYEAQRQGRISFYLTTIGE
EAINIASAAALTPEDLIFPQYREPGVLLWRGFTLQEFANQCFGNKADYGKGRQMPIHYGS
NKLNYFTVSSTIATQIPHAVGAAYSLKMDKKDACAVTYFGDGGTSEGDFHAALNFAAVRE
APVVFICRNNGWAISTPTEDQFRSDGIVVKGQAYGIRSIRVDGNDALAMYSAVHAARSMA
IREHRPVLIEALTYRVGHHSTSDDSTKYRSAEEIEWWRMARDPVTRFRQWIESYGWWNAE
AESEHRYSMRKQMLQAIQVAEKVEKPGVADLFTDVYDVPPSNLVEQEKLLRETVKRHSQE
YPSDVPI
NT seq
1464 nt
NT seq
+upstream
nt +downstream
nt
atggctctttggactagaaaatcaatcaatgctgtcagccatttggtttcaaagctgggt
tttttgggcgtgatcaaccggagttcctggtctcattctttccatcaaagacatcctatt
tcagatgcatgtgctccaaatcttaaaaacccagttgtagatattgtcaatacgccaaca
catttcgctttttctcgttttgagtccaccaaagctgagaaacagtcggattcttttcat
aattttgatgccaatcgacaggttttcattgtgcaacaggtcttggattttccaggagga
gaagtcgcattctctcctgaattgaaattcatttctgaatcccctgaggggagagtacac
tgctatagggtccttgataacaaaggacagattatttcaggcagcacctatgcacaggtg
aataaagaagtagctctaaaaatgtacagtgaaatggtcacacttcaagtgatggatact
atattctatgaagcacaaagacaagggagaatttctttttatctaaccacaattggagaa
gaagcaatcaacattgcatctgcagcagcattaactcctgaagaccttatttttcctcag
tatcgggaaccaggagtgctattatggcgtggtttcaccctgcaagaatttgcgaatcag
tgttttggtaacaaagctgattatgggaaaggcaggcaaatgcctatacactacggatct
aacaagctcaattacttcaccgtgtcatcaacaattgctacacaaattcctcacgctgtt
ggtgcggcatattcattaaagatggacaaaaaagatgcctgtgcagtaacttattttggc
gatggcgggactagtgagggtgactttcatgcggctttaaactttgcggcagttagggag
gcaccagttgtattcatctgtcggaacaatggttgggctataagtacaccaacagaagat
cagtttcgaagtgatggtatagttgttaaaggtcaggcatatggaatacgaagtattcga
gtagatggtaatgatgcgcttgcaatgtacagtgctgttcatgctgcacgtagcatggca
attcgtgaacacagaccagtcttaattgaggcactaacctatcgagtgggacaccactca
acatctgacgattcaaccaagtaccgatcggctgaagagattgaatggtggagaatggca
cgcgaccctgttactcggtttagacagtggatcgaaagttatggttggtggaatgctgag
gctgaatcagagcatagatacagcatgagaaaacagatgttacaagcgattcaagtggct
gagaaagtggagaaaccaggagttgcagacctttttacagatgtatatgatgttccaccg
tccaaccttgttgagcaagagaaattgctgagggaaactgtcaaaagacattcacaggaa
tacccatcagatgttcctatctag
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