Hyphomicrobium sp. MC1: HYPMC_0538
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Entry
HYPMC_0538 CDS
T01557
Symbol
lpdA
Name
(GenBank) Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)
KO
K00382
dihydrolipoyl dehydrogenase [EC:
1.8.1.4
]
Organism
hmc
Hyphomicrobium sp. MC1
Pathway
hmc00010
Glycolysis / Gluconeogenesis
hmc00020
Citrate cycle (TCA cycle)
hmc00260
Glycine, serine and threonine metabolism
hmc00280
Valine, leucine and isoleucine degradation
hmc00310
Lysine degradation
hmc00380
Tryptophan metabolism
hmc00620
Pyruvate metabolism
hmc00630
Glyoxylate and dicarboxylate metabolism
hmc00640
Propanoate metabolism
hmc00670
One carbon pool by folate
hmc00785
Lipoic acid metabolism
hmc01100
Metabolic pathways
hmc01110
Biosynthesis of secondary metabolites
hmc01120
Microbial metabolism in diverse environments
hmc01200
Carbon metabolism
hmc01210
2-Oxocarboxylic acid metabolism
hmc01240
Biosynthesis of cofactors
Module
hmc_M00009
Citrate cycle (TCA cycle, Krebs cycle)
hmc_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
hmc_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
hmc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
HYPMC_0538 (lpdA)
00020 Citrate cycle (TCA cycle)
HYPMC_0538 (lpdA)
00620 Pyruvate metabolism
HYPMC_0538 (lpdA)
00630 Glyoxylate and dicarboxylate metabolism
HYPMC_0538 (lpdA)
00640 Propanoate metabolism
HYPMC_0538 (lpdA)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
HYPMC_0538 (lpdA)
00280 Valine, leucine and isoleucine degradation
HYPMC_0538 (lpdA)
00310 Lysine degradation
HYPMC_0538 (lpdA)
00380 Tryptophan metabolism
HYPMC_0538 (lpdA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HYPMC_0538 (lpdA)
00670 One carbon pool by folate
HYPMC_0538 (lpdA)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hmc04147
]
HYPMC_0538 (lpdA)
Enzymes [BR:
hmc01000
]
1. Oxidoreductases
1.8 Acting on a sulfur group of donors
1.8.1 With NAD+ or NADP+ as acceptor
1.8.1.4 dihydrolipoyl dehydrogenase
HYPMC_0538 (lpdA)
Exosome [BR:
hmc04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
HYPMC_0538 (lpdA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pyr_redox_2
Pyr_redox_dim
Biotin_lipoyl
Pyr_redox
FAD_oxidored
GIDA
Biotin_lipoyl_2
AlaDh_PNT_C
NAD_binding_8
Pyr_redox_3
FAD_binding_3
FAD_binding_2
HI0933_like
GCV_H
Thi4
Motif
Other DBs
NCBI-ProteinID:
CCB63772
UniProt:
F8JAI6
LinkDB
All DBs
Position
528395..530146
Genome browser
AA seq
583 aa
AA seq
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MSKKEIRVPDLGDFKDVPIIEVHVKVGASVAPEDPLITLESDKASFDVPAPEAGKIVDLL
VKVGDKVSEGSVILTLESGAATAPSQPEAPKKTEVAPVASAAKDYSGDADHNCEVLVLGA
GPGGYSAAFRAADLGAKTILVDRWPTLGGVCLNVGCIPSKALLHTAFVVDEAAALAKHGI
SFGAPKVDLQKLAAFKDGVVGKLTGGLASMAKARKVTTLRGTGTFAGAHHLKVRFDDGHE
EAVRFEKAIIAAGSEAVALPFMPSDPRIVDSTGALELRQVPDKMLVIGGGIIGLEMATVY
STLGARLDVVELLDGLMPGADRDLVSTWQKVNARRFDKVMLKTKVVAAEAKRDGIYVTFE
GENAPPEPRRYGLVLVAVGRKPNGKMIAADNAGVAVSERGFIPVDKDMRTNVPHIFAIGD
IADEPMLAHKAVHQGHVAAENAAGKKSFFDVRQVPSVAYTDPEITWAGLTETEAKARGIA
YKKAVFPWAASGRAIANGRDEGFTKLLFDEKTERIMGGAIVGTEAGNLISEICLAIEMGA
DAVDIGKTIHPHPTLSESVGMAAEVAEGVCTDLMPAKSPRPKS
NT seq
1752 nt
NT seq
+upstream
nt +downstream
nt
atgagcaaaaaagaaatccgcgttcccgatctcggtgacttcaaggacgtgcccatcatc
gaggtgcacgtgaaggtgggtgcgagcgttgcgccggaagatccgctgattacgctcgag
agcgataaggcgtcgttcgacgttccggcgccggaagccgggaagatcgtcgatctgctt
gtcaaggttggcgacaaagtgagcgaaggcagcgtgatcctgacgctcgagtcgggcgcg
gcgacggctccatcgcagccggaagctccgaagaagacagaggtcgcacctgtcgcgtct
gctgcgaaagattattccggcgatgcggatcataactgcgaggtgctcgtgctcggcgct
gggccgggtggctattctgcggcgttccgcgcggctgacctcggagcgaagaccatcctt
gtcgatcgctggccgacgctcgggggtgtctgcctgaatgtcggctgcattccgtcgaag
gcgctgttgcacacggctttcgttgtcgacgaagctgcggcgctcgcgaaacacggcatc
tcgttcggggcgccgaaagtcgatttgcaaaagctcgcagccttcaaggatggtgtcgtc
ggcaagttgacgggcggcctcgcttcgatggcgaaggcgcgtaaggtgacgacgttgcgc
ggcacgggcacattcgcgggcgcgcaccatctgaaggtgcggttcgacgatgggcatgaa
gaggccgtgcgctttgagaaggcgatcatcgctgcaggatcggaggcggtcgcgttgccg
ttcatgccatcggatccgcgtatcgtcgattcaacaggcgcgttggaacttcgacaggtt
ccggacaagatgctcgtcatcggtggcggcatcatcgggctcgaaatggcgacggtctat
tcgacgctcggcgcgcggctcgacgtggtcgagttgctcgacggcttgatgccgggggcg
gatcgcgatctcgtcagcacctggcagaaggtcaatgcgcgtcgcttcgacaaggtgatg
ctgaagacgaaagtcgtcgcggcggaagcgaagcgcgacggtatctacgtgacgtttgag
ggcgagaatgcgccgcctgaaccgcggcgatacggtctcgtgctcgtggccgtcggacgc
aagccgaacgggaaaatgatagcggcggataacgcgggcgtagcagtttccgagcgtggc
ttcattccggtcgacaaggacatgcgcacgaatgtcccgcatatctttgccatcggcgat
atcgcagacgagccgatgttggcgcataaggccgttcatcaggggcatgttgcggctgag
aatgccgccggtaaaaaaagtttcttcgatgtgcggcaggtcccgtcggtcgcctatacc
gacccggagattacctgggccggtctgactgagaccgaggccaaggcgcggggaattgct
tacaaaaaagcggtgtttccgtgggcggcttcaggccgggccatcgccaatggccgcgat
gaaggcttcaccaagctgctttttgacgagaaaacagagcggattatgggcggcgccatc
gtcggaacagaggccggaaacctgatttccgagatttgcctggcaatcgagatgggggcc
gacgcggtcgatatcggcaagacaatccatccgcatccgacgctgtcggaatcggtcggc
atggccgccgaggtggcggaaggcgtctgcacggacctgatgccagcgaagtcgccgcgg
ccgaaaagttaa
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