Hylobates moloch (silvery gibbon): 116459126
Help
Entry
116459126 CDS
T08803
Symbol
MAPK1
Name
(RefSeq) mitogen-activated protein kinase 1
KO
K04371
mitogen-activated protein kinase 1/3 [EC:
2.7.11.24
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh01521
EGFR tyrosine kinase inhibitor resistance
hmh01522
Endocrine resistance
hmh01524
Platinum drug resistance
hmh04010
MAPK signaling pathway
hmh04012
ErbB signaling pathway
hmh04014
Ras signaling pathway
hmh04015
Rap1 signaling pathway
hmh04022
cGMP-PKG signaling pathway
hmh04024
cAMP signaling pathway
hmh04062
Chemokine signaling pathway
hmh04066
HIF-1 signaling pathway
hmh04068
FoxO signaling pathway
hmh04071
Sphingolipid signaling pathway
hmh04072
Phospholipase D signaling pathway
hmh04114
Oocyte meiosis
hmh04140
Autophagy - animal
hmh04148
Efferocytosis
hmh04150
mTOR signaling pathway
hmh04151
PI3K-Akt signaling pathway
hmh04210
Apoptosis
hmh04218
Cellular senescence
hmh04261
Adrenergic signaling in cardiomyocytes
hmh04270
Vascular smooth muscle contraction
hmh04350
TGF-beta signaling pathway
hmh04360
Axon guidance
hmh04370
VEGF signaling pathway
hmh04371
Apelin signaling pathway
hmh04380
Osteoclast differentiation
hmh04510
Focal adhesion
hmh04517
IgSF CAM signaling
hmh04520
Adherens junction
hmh04540
Gap junction
hmh04550
Signaling pathways regulating pluripotency of stem cells
hmh04611
Platelet activation
hmh04613
Neutrophil extracellular trap formation
hmh04620
Toll-like receptor signaling pathway
hmh04621
NOD-like receptor signaling pathway
hmh04625
C-type lectin receptor signaling pathway
hmh04650
Natural killer cell mediated cytotoxicity
hmh04657
IL-17 signaling pathway
hmh04658
Th1 and Th2 cell differentiation
hmh04659
Th17 cell differentiation
hmh04660
T cell receptor signaling pathway
hmh04662
B cell receptor signaling pathway
hmh04664
Fc epsilon RI signaling pathway
hmh04666
Fc gamma R-mediated phagocytosis
hmh04668
TNF signaling pathway
hmh04713
Circadian entrainment
hmh04720
Long-term potentiation
hmh04722
Neurotrophin signaling pathway
hmh04723
Retrograde endocannabinoid signaling
hmh04724
Glutamatergic synapse
hmh04725
Cholinergic synapse
hmh04726
Serotonergic synapse
hmh04730
Long-term depression
hmh04810
Regulation of actin cytoskeleton
hmh04910
Insulin signaling pathway
hmh04912
GnRH signaling pathway
hmh04914
Progesterone-mediated oocyte maturation
hmh04915
Estrogen signaling pathway
hmh04916
Melanogenesis
hmh04917
Prolactin signaling pathway
hmh04919
Thyroid hormone signaling pathway
hmh04921
Oxytocin signaling pathway
hmh04926
Relaxin signaling pathway
hmh04928
Parathyroid hormone synthesis, secretion and action
hmh04929
GnRH secretion
hmh04930
Type II diabetes mellitus
hmh04933
AGE-RAGE signaling pathway in diabetic complications
hmh04934
Cushing syndrome
hmh04935
Growth hormone synthesis, secretion and action
hmh04960
Aldosterone-regulated sodium reabsorption
hmh05010
Alzheimer disease
hmh05020
Prion disease
hmh05022
Pathways of neurodegeneration - multiple diseases
hmh05034
Alcoholism
hmh05132
Salmonella infection
hmh05133
Pertussis
hmh05135
Yersinia infection
hmh05140
Leishmaniasis
hmh05142
Chagas disease
hmh05145
Toxoplasmosis
hmh05152
Tuberculosis
hmh05160
Hepatitis C
hmh05161
Hepatitis B
hmh05163
Human cytomegalovirus infection
hmh05164
Influenza A
hmh05165
Human papillomavirus infection
hmh05166
Human T-cell leukemia virus 1 infection
hmh05167
Kaposi sarcoma-associated herpesvirus infection
hmh05170
Human immunodeficiency virus 1 infection
hmh05171
Coronavirus disease - COVID-19
hmh05200
Pathways in cancer
hmh05203
Viral carcinogenesis
hmh05205
Proteoglycans in cancer
hmh05206
MicroRNAs in cancer
hmh05207
Chemical carcinogenesis - receptor activation
hmh05208
Chemical carcinogenesis - reactive oxygen species
hmh05210
Colorectal cancer
hmh05211
Renal cell carcinoma
hmh05212
Pancreatic cancer
hmh05213
Endometrial cancer
hmh05214
Glioma
hmh05215
Prostate cancer
hmh05216
Thyroid cancer
hmh05218
Melanoma
hmh05219
Bladder cancer
hmh05220
Chronic myeloid leukemia
hmh05221
Acute myeloid leukemia
hmh05223
Non-small cell lung cancer
hmh05224
Breast cancer
hmh05225
Hepatocellular carcinoma
hmh05226
Gastric cancer
hmh05230
Central carbon metabolism in cancer
hmh05231
Choline metabolism in cancer
hmh05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
hmh05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
116459126 (MAPK1)
04012 ErbB signaling pathway
116459126 (MAPK1)
04014 Ras signaling pathway
116459126 (MAPK1)
04015 Rap1 signaling pathway
116459126 (MAPK1)
04350 TGF-beta signaling pathway
116459126 (MAPK1)
04370 VEGF signaling pathway
116459126 (MAPK1)
04371 Apelin signaling pathway
116459126 (MAPK1)
04668 TNF signaling pathway
116459126 (MAPK1)
04066 HIF-1 signaling pathway
116459126 (MAPK1)
04068 FoxO signaling pathway
116459126 (MAPK1)
04072 Phospholipase D signaling pathway
116459126 (MAPK1)
04071 Sphingolipid signaling pathway
116459126 (MAPK1)
04024 cAMP signaling pathway
116459126 (MAPK1)
04022 cGMP-PKG signaling pathway
116459126 (MAPK1)
04151 PI3K-Akt signaling pathway
116459126 (MAPK1)
04150 mTOR signaling pathway
116459126 (MAPK1)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
116459126 (MAPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
116459126 (MAPK1)
04148 Efferocytosis
116459126 (MAPK1)
09143 Cell growth and death
04114 Oocyte meiosis
116459126 (MAPK1)
04210 Apoptosis
116459126 (MAPK1)
04218 Cellular senescence
116459126 (MAPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
116459126 (MAPK1)
04520 Adherens junction
116459126 (MAPK1)
04540 Gap junction
116459126 (MAPK1)
04550 Signaling pathways regulating pluripotency of stem cells
116459126 (MAPK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
116459126 (MAPK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
116459126 (MAPK1)
04613 Neutrophil extracellular trap formation
116459126 (MAPK1)
04620 Toll-like receptor signaling pathway
116459126 (MAPK1)
04621 NOD-like receptor signaling pathway
116459126 (MAPK1)
04625 C-type lectin receptor signaling pathway
116459126 (MAPK1)
04650 Natural killer cell mediated cytotoxicity
116459126 (MAPK1)
04660 T cell receptor signaling pathway
116459126 (MAPK1)
04658 Th1 and Th2 cell differentiation
116459126 (MAPK1)
04659 Th17 cell differentiation
116459126 (MAPK1)
04657 IL-17 signaling pathway
116459126 (MAPK1)
04662 B cell receptor signaling pathway
116459126 (MAPK1)
04664 Fc epsilon RI signaling pathway
116459126 (MAPK1)
04666 Fc gamma R-mediated phagocytosis
116459126 (MAPK1)
04062 Chemokine signaling pathway
116459126 (MAPK1)
09152 Endocrine system
04910 Insulin signaling pathway
116459126 (MAPK1)
04929 GnRH secretion
116459126 (MAPK1)
04912 GnRH signaling pathway
116459126 (MAPK1)
04915 Estrogen signaling pathway
116459126 (MAPK1)
04914 Progesterone-mediated oocyte maturation
116459126 (MAPK1)
04917 Prolactin signaling pathway
116459126 (MAPK1)
04921 Oxytocin signaling pathway
116459126 (MAPK1)
04926 Relaxin signaling pathway
116459126 (MAPK1)
04935 Growth hormone synthesis, secretion and action
116459126 (MAPK1)
04919 Thyroid hormone signaling pathway
116459126 (MAPK1)
04928 Parathyroid hormone synthesis, secretion and action
116459126 (MAPK1)
04916 Melanogenesis
116459126 (MAPK1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
116459126 (MAPK1)
04270 Vascular smooth muscle contraction
116459126 (MAPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
116459126 (MAPK1)
09156 Nervous system
04724 Glutamatergic synapse
116459126 (MAPK1)
04725 Cholinergic synapse
116459126 (MAPK1)
04726 Serotonergic synapse
116459126 (MAPK1)
04720 Long-term potentiation
116459126 (MAPK1)
04730 Long-term depression
116459126 (MAPK1)
04723 Retrograde endocannabinoid signaling
116459126 (MAPK1)
04722 Neurotrophin signaling pathway
116459126 (MAPK1)
09158 Development and regeneration
04360 Axon guidance
116459126 (MAPK1)
04380 Osteoclast differentiation
116459126 (MAPK1)
09159 Environmental adaptation
04713 Circadian entrainment
116459126 (MAPK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
116459126 (MAPK1)
05206 MicroRNAs in cancer
116459126 (MAPK1)
05205 Proteoglycans in cancer
116459126 (MAPK1)
05207 Chemical carcinogenesis - receptor activation
116459126 (MAPK1)
05208 Chemical carcinogenesis - reactive oxygen species
116459126 (MAPK1)
05203 Viral carcinogenesis
116459126 (MAPK1)
05230 Central carbon metabolism in cancer
116459126 (MAPK1)
05231 Choline metabolism in cancer
116459126 (MAPK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
116459126 (MAPK1)
09162 Cancer: specific types
05210 Colorectal cancer
116459126 (MAPK1)
05212 Pancreatic cancer
116459126 (MAPK1)
05225 Hepatocellular carcinoma
116459126 (MAPK1)
05226 Gastric cancer
116459126 (MAPK1)
05214 Glioma
116459126 (MAPK1)
05216 Thyroid cancer
116459126 (MAPK1)
05221 Acute myeloid leukemia
116459126 (MAPK1)
05220 Chronic myeloid leukemia
116459126 (MAPK1)
05218 Melanoma
116459126 (MAPK1)
05211 Renal cell carcinoma
116459126 (MAPK1)
05219 Bladder cancer
116459126 (MAPK1)
05215 Prostate cancer
116459126 (MAPK1)
05213 Endometrial cancer
116459126 (MAPK1)
05224 Breast cancer
116459126 (MAPK1)
05223 Non-small cell lung cancer
116459126 (MAPK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
116459126 (MAPK1)
05170 Human immunodeficiency virus 1 infection
116459126 (MAPK1)
05161 Hepatitis B
116459126 (MAPK1)
05160 Hepatitis C
116459126 (MAPK1)
05171 Coronavirus disease - COVID-19
116459126 (MAPK1)
05164 Influenza A
116459126 (MAPK1)
05163 Human cytomegalovirus infection
116459126 (MAPK1)
05167 Kaposi sarcoma-associated herpesvirus infection
116459126 (MAPK1)
05165 Human papillomavirus infection
116459126 (MAPK1)
09171 Infectious disease: bacterial
05132 Salmonella infection
116459126 (MAPK1)
05135 Yersinia infection
116459126 (MAPK1)
05133 Pertussis
116459126 (MAPK1)
05152 Tuberculosis
116459126 (MAPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
116459126 (MAPK1)
05140 Leishmaniasis
116459126 (MAPK1)
05142 Chagas disease
116459126 (MAPK1)
09164 Neurodegenerative disease
05010 Alzheimer disease
116459126 (MAPK1)
05020 Prion disease
116459126 (MAPK1)
05022 Pathways of neurodegeneration - multiple diseases
116459126 (MAPK1)
09165 Substance dependence
05034 Alcoholism
116459126 (MAPK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
116459126 (MAPK1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
116459126 (MAPK1)
04933 AGE-RAGE signaling pathway in diabetic complications
116459126 (MAPK1)
04934 Cushing syndrome
116459126 (MAPK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
116459126 (MAPK1)
01524 Platinum drug resistance
116459126 (MAPK1)
01522 Endocrine resistance
116459126 (MAPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hmh01001
]
116459126 (MAPK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hmh03036
]
116459126 (MAPK1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hmh04147
]
116459126 (MAPK1)
Enzymes [BR:
hmh01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
116459126 (MAPK1)
Protein kinases [BR:
hmh01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
116459126 (MAPK1)
Chromosome and associated proteins [BR:
hmh03036
]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Protein kinases
116459126 (MAPK1)
Exosome [BR:
hmh04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
116459126 (MAPK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
STATB_N
Haspin_kinase
FTA2
Kdo
Motif
Other DBs
NCBI-GeneID:
116459126
NCBI-ProteinID:
XP_031995302
LinkDB
All DBs
Position
Unknown
AA seq
360 aa
AA seq
DB search
MAAAAAAGAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFE
HQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQH
LSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDH
TGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHI
LGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHK
RIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
NT seq
1083 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcggcggcgggcgcgggcccggagatggtccgcgggcaggtgttcgac
gtggggccgcgctacaccaacctctcgtacatcggcgagggcgcctacggcatggtgtgc
tctgcgtatgataatgtcaacaaagttcgagtagccatcaagaaaatcagcccctttgag
caccagacctactgccagagaaccctgagggagataaaaatcttactgcgcttcagacat
gagaacatcattggaatcaatgacattattcgagcaccaaccatcgagcaaatgaaagat
gtatatatagtacaggacctcatggaaacagatctttacaagctcttgaagacacaacac
ctcagcaacgaccatatctgctattttctttaccagatcctcagagggttaaaatatatc
cattcagctaacgttctgcaccgtgacctcaagccttccaacctgctgctcaacaccacc
tgtgatctcaagatctgtgactttggcctggcccgtgttgcagatccagaccatgatcac
acagggttcctgacagaatatgtggccacacgttggtacagggctccagaaattatgttg
aattccaagggctacaccaagtccattgatatttggtctgtaggctgcattctggcagaa
atgctttctaacaggcccatctttccagggaagcattatcttgaccagctgaaccacatt
ctgggtattcttggatccccatcacaagaagacctgaattgtataataaatttaaaagct
aggaactatttgctttctcttccacacaaaaataaggtgccatggaacaggctgttccca
aatgctgactccaaagctctggacttactggacaaaatgttgacattcaacccacacaag
aggattgaagtagaacaggctctggcccacccatatctggaacagtattacgacccgagt
gacgagcccatcgccgaagcaccattcaagtttgacatggaattggatgacttgcctaag
gaaaagctcaaagaactaatttttgaagagactgctagattccagccaggatacagatct
taa
DBGET
integrated database retrieval system