KEGG   Hylobates moloch (silvery gibbon): 116459649
Entry
116459649         CDS       T08803                                 
Symbol
MAPK13
Name
(RefSeq) mitogen-activated protein kinase 13
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
hmh  Hylobates moloch (silvery gibbon)
Pathway
hmh01522  Endocrine resistance
hmh04010  MAPK signaling pathway
hmh04015  Rap1 signaling pathway
hmh04068  FoxO signaling pathway
hmh04071  Sphingolipid signaling pathway
hmh04114  Oocyte meiosis
hmh04148  Efferocytosis
hmh04218  Cellular senescence
hmh04261  Adrenergic signaling in cardiomyocytes
hmh04370  VEGF signaling pathway
hmh04380  Osteoclast differentiation
hmh04550  Signaling pathways regulating pluripotency of stem cells
hmh04611  Platelet activation
hmh04613  Neutrophil extracellular trap formation
hmh04620  Toll-like receptor signaling pathway
hmh04621  NOD-like receptor signaling pathway
hmh04622  RIG-I-like receptor signaling pathway
hmh04625  C-type lectin receptor signaling pathway
hmh04657  IL-17 signaling pathway
hmh04658  Th1 and Th2 cell differentiation
hmh04659  Th17 cell differentiation
hmh04660  T cell receptor signaling pathway
hmh04664  Fc epsilon RI signaling pathway
hmh04668  TNF signaling pathway
hmh04670  Leukocyte transendothelial migration
hmh04714  Thermogenesis
hmh04722  Neurotrophin signaling pathway
hmh04723  Retrograde endocannabinoid signaling
hmh04728  Dopaminergic synapse
hmh04750  Inflammatory mediator regulation of TRP channels
hmh04912  GnRH signaling pathway
hmh04914  Progesterone-mediated oocyte maturation
hmh04917  Prolactin signaling pathway
hmh04926  Relaxin signaling pathway
hmh04932  Non-alcoholic fatty liver disease
hmh04933  AGE-RAGE signaling pathway in diabetic complications
hmh04935  Growth hormone synthesis, secretion and action
hmh04936  Alcoholic liver disease
hmh05014  Amyotrophic lateral sclerosis
hmh05020  Prion disease
hmh05022  Pathways of neurodegeneration - multiple diseases
hmh05132  Salmonella infection
hmh05133  Pertussis
hmh05135  Yersinia infection
hmh05140  Leishmaniasis
hmh05142  Chagas disease
hmh05145  Toxoplasmosis
hmh05152  Tuberculosis
hmh05161  Hepatitis B
hmh05163  Human cytomegalovirus infection
hmh05167  Kaposi sarcoma-associated herpesvirus infection
hmh05169  Epstein-Barr virus infection
hmh05170  Human immunodeficiency virus 1 infection
hmh05171  Coronavirus disease - COVID-19
hmh05205  Proteoglycans in cancer
hmh05208  Chemical carcinogenesis - reactive oxygen species
hmh05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hmh05415  Diabetic cardiomyopathy
hmh05417  Lipid and atherosclerosis
hmh05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hmh00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    116459649 (MAPK13)
   04015 Rap1 signaling pathway
    116459649 (MAPK13)
   04370 VEGF signaling pathway
    116459649 (MAPK13)
   04668 TNF signaling pathway
    116459649 (MAPK13)
   04068 FoxO signaling pathway
    116459649 (MAPK13)
   04071 Sphingolipid signaling pathway
    116459649 (MAPK13)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    116459649 (MAPK13)
  09143 Cell growth and death
   04114 Oocyte meiosis
    116459649 (MAPK13)
   04218 Cellular senescence
    116459649 (MAPK13)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    116459649 (MAPK13)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    116459649 (MAPK13)
   04613 Neutrophil extracellular trap formation
    116459649 (MAPK13)
   04620 Toll-like receptor signaling pathway
    116459649 (MAPK13)
   04621 NOD-like receptor signaling pathway
    116459649 (MAPK13)
   04622 RIG-I-like receptor signaling pathway
    116459649 (MAPK13)
   04625 C-type lectin receptor signaling pathway
    116459649 (MAPK13)
   04660 T cell receptor signaling pathway
    116459649 (MAPK13)
   04658 Th1 and Th2 cell differentiation
    116459649 (MAPK13)
   04659 Th17 cell differentiation
    116459649 (MAPK13)
   04657 IL-17 signaling pathway
    116459649 (MAPK13)
   04664 Fc epsilon RI signaling pathway
    116459649 (MAPK13)
   04670 Leukocyte transendothelial migration
    116459649 (MAPK13)
  09152 Endocrine system
   04912 GnRH signaling pathway
    116459649 (MAPK13)
   04914 Progesterone-mediated oocyte maturation
    116459649 (MAPK13)
   04917 Prolactin signaling pathway
    116459649 (MAPK13)
   04926 Relaxin signaling pathway
    116459649 (MAPK13)
   04935 Growth hormone synthesis, secretion and action
    116459649 (MAPK13)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    116459649 (MAPK13)
  09156 Nervous system
   04728 Dopaminergic synapse
    116459649 (MAPK13)
   04723 Retrograde endocannabinoid signaling
    116459649 (MAPK13)
   04722 Neurotrophin signaling pathway
    116459649 (MAPK13)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    116459649 (MAPK13)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    116459649 (MAPK13)
  09159 Environmental adaptation
   04714 Thermogenesis
    116459649 (MAPK13)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    116459649 (MAPK13)
   05208 Chemical carcinogenesis - reactive oxygen species
    116459649 (MAPK13)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    116459649 (MAPK13)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    116459649 (MAPK13)
   05161 Hepatitis B
    116459649 (MAPK13)
   05171 Coronavirus disease - COVID-19
    116459649 (MAPK13)
   05163 Human cytomegalovirus infection
    116459649 (MAPK13)
   05167 Kaposi sarcoma-associated herpesvirus infection
    116459649 (MAPK13)
   05169 Epstein-Barr virus infection
    116459649 (MAPK13)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    116459649 (MAPK13)
   05135 Yersinia infection
    116459649 (MAPK13)
   05133 Pertussis
    116459649 (MAPK13)
   05152 Tuberculosis
    116459649 (MAPK13)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    116459649 (MAPK13)
   05140 Leishmaniasis
    116459649 (MAPK13)
   05142 Chagas disease
    116459649 (MAPK13)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    116459649 (MAPK13)
   05020 Prion disease
    116459649 (MAPK13)
   05022 Pathways of neurodegeneration - multiple diseases
    116459649 (MAPK13)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    116459649 (MAPK13)
   05418 Fluid shear stress and atherosclerosis
    116459649 (MAPK13)
   05415 Diabetic cardiomyopathy
    116459649 (MAPK13)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    116459649 (MAPK13)
   04932 Non-alcoholic fatty liver disease
    116459649 (MAPK13)
   04933 AGE-RAGE signaling pathway in diabetic complications
    116459649 (MAPK13)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    116459649 (MAPK13)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hmh01001]
    116459649 (MAPK13)
Enzymes [BR:hmh01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     116459649 (MAPK13)
Protein kinases [BR:hmh01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   116459649 (MAPK13)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kinase-like Kdo US2
Other DBs
NCBI-GeneID: 116459649
NCBI-ProteinID: XP_031996151
LinkDB
Position
Unknown
AA seq 365 aa
MSLTRKKGFYKQDVNKTAWELPKTYVSPTHVGSGAYGAVCSAIDKRSGEKVAIKKLSRPF
QSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFHDFYLVMPFMQTDLQKIMGM
EFSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEMT
GYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVTG
VPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTAA
QALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPIARKDSRRR
SGMKL
NT seq 1098 nt   +upstreamnt  +downstreamnt
atgagcctcacccggaaaaagggcttctacaagcaggacgtcaacaagaccgcctgggag
ctgcccaagacctacgtgtccccgacgcacgtcggcagcggggcctatggcgccgtgtgc
tcggccatcgacaagcggtcaggggagaaggtggccatcaagaagctgagccggcccttt
cagtccgagatcttcgccaagcgcgcctaccgggagctgctgctgctgaagcatatgcag
catgagaacgtcattgggctcctggatgtcttcaccccagcctcctccctgcgcaacttc
catgacttctacctggtgatgcccttcatgcagacagatctgcagaagatcatggggatg
gagttcagtgaggagaagatccagtacctggtgtatcagatgctcaaaggccttaagtac
atccactcggctggggtcgtgcacagggacctgaagccaggcaacctggctgtgaacgag
gactgtgaactgaagattctggattttgggctggcgcgacatgcagacgccgagatgact
ggctacgtggtgacccgctggtaccgggcccccgaggtgatcctcagctggatgcactac
aaccagacggtggacatctggtctgtgggctgtatcatggcagagatgctgacagggaaa
actctgttcaaggggaaagattacctggaccagctgacccagatcctgaaagtgaccggg
gtgcctggcacggagtttgtgcagaagctgaacgacaaagcggccaaatcctacatccag
tccctgccgcagacccccaggaaggatttcactcagctcttcccacgggccagcccccag
gctgcggacctgctggagaagatgctggagctagacgtggacaagcgcctgacagccgcg
caggccctcacccatcccttctttgagcccttccgggaccctgaggaagagacggaggcc
cagcagccgtttgatgattccttagaacacgagaaactcacagtggatgaatggaagcag
cacatctacaaggagattgtgaacttcagccccattgcccggaaggactcgcggcgccgg
agtggcatgaagctgtag

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