Hylobates moloch (silvery gibbon): 116459712
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Entry
116459712 CDS
T08803
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh00270
Cysteine and methionine metabolism
hmh00480
Glutathione metabolism
hmh01100
Metabolic pathways
hmh01240
Biosynthesis of cofactors
hmh04216
Ferroptosis
Module
hmh_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
116459712 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
116459712 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
116459712 (GCLC)
Enzymes [BR:
hmh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
116459712 (GCLC)
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Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
116459712
NCBI-ProteinID:
XP_031996304
LinkDB
All DBs
Position
Unknown
AA seq
637 aa
AA seq
DB search
MGLLSQGSPLSWEETKRHADHVRRHGILQFLHIYHAVKDRHKDVLKWGDEVEYMLVSFDH
ENKKVRLVLSGEKVLEILQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EANMRKRRKEATSILEENQALCTITSFPRLGCPGFTLPEVKPNPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPEDDEASRASKPDHIYMDA
MGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGVI
SASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSKCGEKYNDIDLTIDKEIYEQLLQ
EGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSDI
GWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAVL
QGMFYFRKDICKGGNAVVDGCSKAQNSTELAAEEYTLMSIDTIINGKEGVFPGLIPILNS
YLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIANHPDYKQDSVITDEMNYS
LILKCNQIADELCECPELLGSAFRKVKYSGSKTDSSN
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcccagggctcgccgctgagctgggaggaaaccaagcgccatgccgac
cacgtgcggcggcacgggattctccagttcctgcacatctaccacgccgtcaaggaccgg
cacaaggacgttctcaagtggggcgatgaggtggaatacatgttggtatcttttgatcat
gaaaataaaaaagtccggttggtcctgtctggggagaaagttcttgaaattctacaagag
aagggggaaaggacaaacccaaaccatcctacgctttggagaccagagtatgggagttac
atgattgaagggacaccaggacagccctacggaggaacaatgtccgagttcaacacagtt
gaggccaacatgcgaaaacgccggaaggaggctacttctatattagaagaaaatcaggct
ctttgcacaataacttcatttcccagattaggctgtcctgggttcacactgcccgaggtc
aaacccaacccagtggaaggaggagcttccaagtccctcttcttcccagatgaagcaata
aacaagcaccctcgcttcagtaccttaacaagaaatatccgacataggagaggagaaaag
gttgtcatcaatgtaccaatatttaaggacaagaatacaccatctccatttatagaaacg
tttcctgaggatgatgaagcttcaagggcctctaagccggatcatatttacatggatgcc
atgggatttggaatgggcaattgctgtctccaggtgacattccaagcctgcagtatatct
gaggccagatacctttatgatcagttggctactatctgtccaattgttatggctttgagt
gctgcatctcccttttaccgaggttacgtgtcagacattgattgtcgctggggagtgatt
tctgcatctgtagatgatagaactcgggaggagagaggactggagccattgaagaacaat
aactataggatcagtaaatcccgatatgactcaatagacagctatttatctaagtgtggt
gagaaatataatgacatcgacttgacgatagataaagagatctacgaacagctgttgcag
gaaggcattgatcatctcctggcccagcatgttgctcatctctttattagagacccactg
acactgtttgaagagaaaatacacctggatgatgccaacgagtctgaccattttgagaat
atccagtccacaaattggcagacaatgagatttaagccccctcctccaaactcagacatt
ggatggagagtagaatttcgacccatggaggtgcaattaacagactttgagaactctgcc
tatgtggtgttcgtggtactgctcaccagagtcatcctttcctacaaattggattttctc
attccactgtcaaaggttgatgagaacatgaaggtagcacagaaaagagatgctgtcttg
cagggaatgttttatttcaggaaagatatttgcaaaggtggcaacgcagtggtggatggt
tgcagcaaggcgcagaacagcacggagctcgctgcagaggagtacaccctcatgagcata
gacaccatcatcaatgggaaggaaggtgtgtttcctggactgatcccaattctgaactct
taccttgaaaacatggaagtggatgtggacaccagatgtagtattctgaactacctaaag
ctaattaagaagagagcatctggagaactaatgacagttgccagatggatgagggagttt
atcgcaaaccatcctgactacaagcaagacagtgtcataactgatgaaatgaattatagc
cttattttgaagtgtaaccaaattgcagatgaattatgtgaatgcccagagttacttgga
tcagcatttaggaaagtaaaatatagtggaagtaaaactgactcatccaactag
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