Hylobates moloch (silvery gibbon): 116461805 Help Entry 116461805         CDS       T08803                                  Symbol ADCY6 Name (RefSeq) adenylate cyclase type 6   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism hmh  Hylobates moloch (silvery gibbon) Pathway hmh00230   Purine metabolism hmh01100   Metabolic pathways hmh01522   Endocrine resistance hmh04015   Rap1 signaling pathway hmh04022   cGMP-PKG signaling pathway hmh04024   cAMP signaling pathway hmh04062   Chemokine signaling pathway hmh04072   Phospholipase D signaling pathway hmh04081   Hormone signaling hmh04082   Neuroactive ligand signaling hmh04114   Oocyte meiosis hmh04211   Longevity regulating pathway hmh04213   Longevity regulating pathway - multiple species hmh04261   Adrenergic signaling in cardiomyocytes hmh04270   Vascular smooth muscle contraction hmh04371   Apelin signaling pathway hmh04540   Gap junction hmh04611   Platelet activation hmh04713   Circadian entrainment hmh04714   Thermogenesis hmh04723   Retrograde endocannabinoid signaling hmh04724   Glutamatergic synapse hmh04725   Cholinergic synapse hmh04727   GABAergic synapse hmh04742   Taste transduction hmh04750   Inflammatory mediator regulation of TRP channels hmh04911   Insulin secretion hmh04912   GnRH signaling pathway hmh04913   Ovarian steroidogenesis hmh04914   Progesterone-mediated oocyte maturation hmh04915   Estrogen signaling pathway hmh04916   Melanogenesis hmh04918   Thyroid hormone synthesis hmh04921   Oxytocin signaling pathway hmh04923   Regulation of lipolysis in adipocytes hmh04924   Renin secretion hmh04925   Aldosterone synthesis and secretion hmh04926   Relaxin signaling pathway hmh04927   Cortisol synthesis and secretion hmh04928   Parathyroid hormone synthesis, secretion and action hmh04934   Cushing syndrome hmh04935   Growth hormone synthesis, secretion and action hmh04961   Endocrine and other factor-regulated calcium reabsorption hmh04962   Vasopressin-regulated water reabsorption hmh04970   Salivary secretion hmh04971   Gastric acid secretion hmh04972   Pancreatic secretion hmh04976   Bile secretion hmh05032   Morphine addiction hmh05163   Human cytomegalovirus infection hmh05166   Human T-cell leukemia virus 1 infection hmh05200   Pathways in cancer hmh05207   Chemical carcinogenesis - receptor activation hmh05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:hmh00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     116461805 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     116461805 (ADCY6)    04072 Phospholipase D signaling pathway     116461805 (ADCY6)    04024 cAMP signaling pathway     116461805 (ADCY6)    04022 cGMP-PKG signaling pathway     116461805 (ADCY6)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     116461805 (ADCY6)    04081 Hormone signaling     116461805 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     116461805 (ADCY6)    04062 Chemokine signaling pathway     116461805 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     116461805 (ADCY6)    04923 Regulation of lipolysis in adipocytes     116461805 (ADCY6)    04913 Ovarian steroidogenesis     116461805 (ADCY6)    04915 Estrogen signaling pathway     116461805 (ADCY6)    04921 Oxytocin signaling pathway     116461805 (ADCY6)    04926 Relaxin signaling pathway     116461805 (ADCY6)    04935 Growth hormone synthesis, secretion and action     116461805 (ADCY6)    04918 Thyroid hormone synthesis     116461805 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     116461805 (ADCY6)    04924 Renin secretion     116461805 (ADCY6)    04925 Aldosterone synthesis and secretion     116461805 (ADCY6)    04927 Cortisol synthesis and secretion     116461805 (ADCY6)   09154 Digestive system    04970 Salivary secretion     116461805 (ADCY6)    04971 Gastric acid secretion     116461805 (ADCY6)    04972 Pancreatic secretion     116461805 (ADCY6)    04976 Bile secretion     116461805 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     116461805 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     116461805 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     116461805 (ADCY6)    04727 GABAergic synapse     116461805 (ADCY6)    04725 Cholinergic synapse     116461805 (ADCY6)    04723 Retrograde endocannabinoid signaling     116461805 (ADCY6)   09157 Sensory system    04742 Taste transduction     116461805 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     116461805 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     116461805 (ADCY6)    04213 Longevity regulating pathway - multiple species     116461805 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     116461805 (ADCY6)    04714 Thermogenesis     116461805 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     116461805 (ADCY6)    05207 Chemical carcinogenesis - receptor activation     116461805 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     116461805 (ADCY6)    05163 Human cytomegalovirus infection     116461805 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     116461805 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     116461805 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     116461805 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     116461805 (ADCY6) Enzymes [BR:hmh01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      116461805 (ADCY6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  116461805 NCBI-ProteinID:  XP_031999611 LinkDB All DBs Position Unknown AA seq 1168 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQKRSRRRGTRAGGFCTPRYMSCLRDAEPPSPTPAGP PRCPWQDDAFIRRGGPGKGKELGLRAVALGFEDTEVTTTAGGTAEVAPDTVPRSGRSCWR RLVQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPAHPQPAY VALLACAAALFVGLMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAADPRSPSAGLW CPVFFVYIAYTLLPIRMRAAVLSGLGLSTLHLILAWQLNRGDAFVWKQLGANVLLFLCTN VIGICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINT KKEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHC LRIKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRV HCGVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNA YLKEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLMPRWVPDRAFSRTKDSKAFR QMGIDDSSKDNRGTQDALNPEDEVDEFLSRAIDARSIDQLRKDHVRRFLLTFQREDLEKK YSRKVDPRFGAYVACALLVFCFICFIQLLIFPHSTLMLGIYASIFLLLLITVLICAVYSC GSLFPKALQRLSRSIVRSRAHSTAVGIFSVLLVFTSAVANMFTCNHTPIRTCAARMLNLT PADITACHLQQLNYSLGLDAPLCEGATPTCSFPEYFIGNMLLSLLASSVFLHISSIGKLA MIFVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGLDCPAAGRVALKYMTPV ILLVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHF LARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIIS EERFRQLEKIKTIGSTYMAASGLNASTYDQVGRSHITALADYAMRLMEQMKHINEHSFNN FQMKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKG YQLECRGVVKVKGKGEMTTYFLNGGPSS NT seq 3507 nt NT seq  +upstreamnt  +downstreamnt atgtcatggtttagtggcctcctggtccctaaagtggatgaacggaaaacagcctggggt gaacgcaatgggcagaagcgttcgcggcgccgtggcactcgggcaggtggcttctgcacg ccccgctatatgagctgcctccgggatgcagagccacccagccccacccctgcgggcccc cctcggtgcccctggcaggatgacgccttcatccggaggggcggcccaggcaagggcaag gaactggggctgcgggcagtggccctgggcttcgaggacaccgaggtgacaacgacagcg ggcggcacggctgaggtggcgcccgacacggtgcccaggagtgggcgatcctgctggcgc cgtctggtgcaggtgttccagtcgaagcagttccgttcggccaagctggagcgcctgtac cagcggtacttcttccagatgaaccagagcagcctgacgctgctgatggcggtgctggtg ctgctcacggccgtgctgctggctttccacgctgcacccgcccaccctcagcctgcctat gtggcactgttggcctgcgccgccgccctgttcgtggggctcatggtggtgtgtaaccgg catagcttccgccaggactccatgtgggtggtgagctacgtggtgctgggcatcctggcg gcagtgcaggtcgggggcgccctcgctgcagacccgcgcagcccctctgcgggcctctgg tgccctgtgttctttgtctacatcgcctacacgctcctccccatccgcatgcgggctgcc gtcctcagcggcctgggcctctccaccttgcatttgatcttggcctggcaacttaaccgt ggtgatgccttcgtctggaagcagcttggtgccaatgtgctgctgttcctctgcaccaac gtcattggcatctgcacacactatccagcagaggtgtctcagcgccaggcctttcaggag acccgcggttacatccaggcccggctccacctgcagcatgagaatcggcagcaggagcgg ctgctgctgtcggtattgccccagcacgttgccatggagatgaaagaagacatcaacaca aaaaaagaagacatgatgttccacaagatctacatacagaagcatgacaatgtcagcatc ctgtttgcagacattgagggcttcaccagcctggcatcccagtgcactgcgcaggagctg gtcatgaccctgaatgagctctttgcccggtttgacaagctggctgcggagaatcactgc ctgaggatcaagatcttgggggactgttactactgtgtgtcagggctgccagaggcccgg gccgaccatgcccactgctgtgtggagatgggggtagacatgatcgaggccatctcgctg gtacgtgaggtgacaggtgtgaatgtgaacatgcgcgtgggcatccacagcggacgcgtg cactgcggcgtccttggcttgcggaaatggcagttcgatgtgtggtccaatgatgtgacc ctggccaaccacatggaggcaggaggccgggctggccgcatccacatcactcgggcaaca ctgcagtacctgaatggggactacgaggtggagccaggccgtggtggcgagcgcaacgcg tacctcaaggagcagcacattgagactttcctgatcctgggcgccagccagaaacggaaa gaggagaaggccatgctggccaagctgcagcggactcgggccaactccatggaagggctg atgcctcgctgggtgcctgatcgcgccttctcccggaccaaggactccaaggccttccgc cagatgggcattgatgattccagcaaagacaaccggggcacccaagatgccctgaaccct gaggatgaggtggatgagttcctgagccgtgccatcgatgcccgcagcattgatcagctg cggaaggaccatgtgcgccggtttctgctcaccttccagagagaggatcttgagaagaag tactcccggaaggtggatccccgcttcggagcctacgttgcctgtgccctgttggtcttc tgcttcatctgcttcatccagcttctcatcttcccacactccaccctgatgcttgggatc tatgccagcatcttcctgctgctgctgatcaccgtgctgatctgtgccgtgtactcctgt ggttctctgttccctaaggccctgcaacgtctgtcccgcagcatcgtccgctcacgggca catagcaccgcagttggtatcttttccgtcctgcttgtgtttacttctgccgttgccaac atgttcacctgtaaccacacccccatacggacctgtgcagcgcggatgctgaatttaaca cctgctgacatcactgcctgccacctgcagcagctcaattactctctgggcctggatgct cccctgtgtgagggcgccacgcccacctgcagcttccctgagtacttcatcgggaacatg ctgctgagtctcttggccagctctgtcttcctgcacatcagcagcatcgggaagttggcc atgatctttgtcttggggctcatctatttggtgctgcttctgctgggtcccccagccacc atctttgacaactatgacctactgcttggcgtccatggcttggcttcttccaatgagacc tttgatgggctggactgtccagctgcagggagggtggccctcaaatatatgacccctgtg attctgctggtgtttgcgctggcgctgtatctgcatgctcagcaggtggagtcgactgcc cgcctagacttcctctggaaactacaggcaacaggggagaaggaggagatggaggagcta caggcatacaaccggaggctgctgcataacattctgcccaaggacgtggcggcccacttc ctggcccgggagcgccgcaatgatgaactctactatcagtcgtgtgagtgtgtggctgtt atgtttgcctccattgccaacttctctgagttctatgtggagctggaggcaaacaatgag ggtgtcgagtgcctgcggctgctcaacgagatcatcgctgactttgatgagattatcagc gaggagcggttccggcagctggaaaagatcaagacgatcggcagcacctacatggccgcc tcagggctgaacgccagcacctacgatcaggtgggccgttcccacatcactgccctggct gactacgccatgcggctcatggagcagatgaagcacatcaatgagcactccttcaacaat ttccagatgaagattgggctgaacatgggcccagtcgtggcaggtgtcatcggggctcgg aagccacagtatgacatctgggggaacacagtgaatgtctctagtcgtatggacagcacg ggggtccccgaccgaatccaggtgaccacggacctgtaccaggttctagctgccaagggc taccagctggagtgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacctac ttcctcaatgggggccccagcagttag

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