KEGG   Hylobates moloch (silvery gibbon): 116466571
Entry
116466571         CDS       T08803                                 
Symbol
HRAS
Name
(RefSeq) GTPase HRas isoform X3
  KO
K02833  GTPase HRas
Organism
hmh  Hylobates moloch (silvery gibbon)
Pathway
hmh01521  EGFR tyrosine kinase inhibitor resistance
hmh01522  Endocrine resistance
hmh04010  MAPK signaling pathway
hmh04012  ErbB signaling pathway
hmh04014  Ras signaling pathway
hmh04015  Rap1 signaling pathway
hmh04062  Chemokine signaling pathway
hmh04068  FoxO signaling pathway
hmh04071  Sphingolipid signaling pathway
hmh04072  Phospholipase D signaling pathway
hmh04137  Mitophagy - animal
hmh04140  Autophagy - animal
hmh04144  Endocytosis
hmh04150  mTOR signaling pathway
hmh04151  PI3K-Akt signaling pathway
hmh04210  Apoptosis
hmh04211  Longevity regulating pathway
hmh04213  Longevity regulating pathway - multiple species
hmh04218  Cellular senescence
hmh04360  Axon guidance
hmh04370  VEGF signaling pathway
hmh04371  Apelin signaling pathway
hmh04510  Focal adhesion
hmh04540  Gap junction
hmh04550  Signaling pathways regulating pluripotency of stem cells
hmh04625  C-type lectin receptor signaling pathway
hmh04630  JAK-STAT signaling pathway
hmh04650  Natural killer cell mediated cytotoxicity
hmh04660  T cell receptor signaling pathway
hmh04662  B cell receptor signaling pathway
hmh04664  Fc epsilon RI signaling pathway
hmh04714  Thermogenesis
hmh04720  Long-term potentiation
hmh04722  Neurotrophin signaling pathway
hmh04725  Cholinergic synapse
hmh04726  Serotonergic synapse
hmh04730  Long-term depression
hmh04810  Regulation of actin cytoskeleton
hmh04910  Insulin signaling pathway
hmh04912  GnRH signaling pathway
hmh04915  Estrogen signaling pathway
hmh04916  Melanogenesis
hmh04917  Prolactin signaling pathway
hmh04919  Thyroid hormone signaling pathway
hmh04921  Oxytocin signaling pathway
hmh04926  Relaxin signaling pathway
hmh04929  GnRH secretion
hmh04933  AGE-RAGE signaling pathway in diabetic complications
hmh04935  Growth hormone synthesis, secretion and action
hmh05010  Alzheimer disease
hmh05022  Pathways of neurodegeneration - multiple diseases
hmh05034  Alcoholism
hmh05132  Salmonella infection
hmh05160  Hepatitis C
hmh05161  Hepatitis B
hmh05163  Human cytomegalovirus infection
hmh05165  Human papillomavirus infection
hmh05166  Human T-cell leukemia virus 1 infection
hmh05167  Kaposi sarcoma-associated herpesvirus infection
hmh05170  Human immunodeficiency virus 1 infection
hmh05200  Pathways in cancer
hmh05203  Viral carcinogenesis
hmh05205  Proteoglycans in cancer
hmh05206  MicroRNAs in cancer
hmh05207  Chemical carcinogenesis - receptor activation
hmh05208  Chemical carcinogenesis - reactive oxygen species
hmh05210  Colorectal cancer
hmh05211  Renal cell carcinoma
hmh05213  Endometrial cancer
hmh05214  Glioma
hmh05215  Prostate cancer
hmh05216  Thyroid cancer
hmh05218  Melanoma
hmh05219  Bladder cancer
hmh05220  Chronic myeloid leukemia
hmh05221  Acute myeloid leukemia
hmh05223  Non-small cell lung cancer
hmh05224  Breast cancer
hmh05225  Hepatocellular carcinoma
hmh05226  Gastric cancer
hmh05230  Central carbon metabolism in cancer
hmh05231  Choline metabolism in cancer
hmh05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hmh05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hmh00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    116466571 (HRAS)
   04015 Rap1 signaling pathway
    116466571 (HRAS)
   04630 JAK-STAT signaling pathway
    116466571 (HRAS)
   04068 FoxO signaling pathway
    116466571 (HRAS)
   04072 Phospholipase D signaling pathway
    116466571 (HRAS)
   04071 Sphingolipid signaling pathway
    116466571 (HRAS)
   04151 PI3K-Akt signaling pathway
    116466571 (HRAS)
   04150 mTOR signaling pathway
    116466571 (HRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    116466571 (HRAS)
   04140 Autophagy - animal
    116466571 (HRAS)
   04137 Mitophagy - animal
    116466571 (HRAS)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    116466571 (HRAS)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    116466571 (HRAS)
   04660 T cell receptor signaling pathway
    116466571 (HRAS)
   04662 B cell receptor signaling pathway
    116466571 (HRAS)
   04664 Fc epsilon RI signaling pathway
    116466571 (HRAS)
   04062 Chemokine signaling pathway
    116466571 (HRAS)
  09152 Endocrine system
   04929 GnRH secretion
    116466571 (HRAS)
   04915 Estrogen signaling pathway
    116466571 (HRAS)
   04917 Prolactin signaling pathway
    116466571 (HRAS)
   04921 Oxytocin signaling pathway
    116466571 (HRAS)
   04926 Relaxin signaling pathway
    116466571 (HRAS)
   04935 Growth hormone synthesis, secretion and action
    116466571 (HRAS)
   04919 Thyroid hormone signaling pathway
    116466571 (HRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    116466571 (HRAS)
   04726 Serotonergic synapse
    116466571 (HRAS)
   04720 Long-term potentiation
    116466571 (HRAS)
   04730 Long-term depression
    116466571 (HRAS)
   04722 Neurotrophin signaling pathway
    116466571 (HRAS)
  09158 Development and regeneration
   04360 Axon guidance
    116466571 (HRAS)
  09149 Aging
   04211 Longevity regulating pathway
    116466571 (HRAS)
   04213 Longevity regulating pathway - multiple species
    116466571 (HRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    116466571 (HRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    116466571 (HRAS)
   05206 MicroRNAs in cancer
    116466571 (HRAS)
   05205 Proteoglycans in cancer
    116466571 (HRAS)
   05207 Chemical carcinogenesis - receptor activation
    116466571 (HRAS)
   05208 Chemical carcinogenesis - reactive oxygen species
    116466571 (HRAS)
   05203 Viral carcinogenesis
    116466571 (HRAS)
   05230 Central carbon metabolism in cancer
    116466571 (HRAS)
   05231 Choline metabolism in cancer
    116466571 (HRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    116466571 (HRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    116466571 (HRAS)
   05225 Hepatocellular carcinoma
    116466571 (HRAS)
   05226 Gastric cancer
    116466571 (HRAS)
   05214 Glioma
    116466571 (HRAS)
   05216 Thyroid cancer
    116466571 (HRAS)
   05221 Acute myeloid leukemia
    116466571 (HRAS)
   05220 Chronic myeloid leukemia
    116466571 (HRAS)
   05218 Melanoma
    116466571 (HRAS)
   05211 Renal cell carcinoma
    116466571 (HRAS)
   05219 Bladder cancer
    116466571 (HRAS)
   05215 Prostate cancer
    116466571 (HRAS)
   05213 Endometrial cancer
    116466571 (HRAS)
   05224 Breast cancer
    116466571 (HRAS)
   05223 Non-small cell lung cancer
    116466571 (HRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    116466571 (HRAS)
   05170 Human immunodeficiency virus 1 infection
    116466571 (HRAS)
   05161 Hepatitis B
    116466571 (HRAS)
   05160 Hepatitis C
    116466571 (HRAS)
   05163 Human cytomegalovirus infection
    116466571 (HRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    116466571 (HRAS)
   05165 Human papillomavirus infection
    116466571 (HRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    116466571 (HRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    116466571 (HRAS)
  09165 Substance dependence
   05034 Alcoholism
    116466571 (HRAS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    116466571 (HRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    116466571 (HRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    116466571 (HRAS)
   01522 Endocrine resistance
    116466571 (HRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hmh04131]
    116466571 (HRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hmh04147]
    116466571 (HRAS)
   04031 GTP-binding proteins [BR:hmh04031]
    116466571 (HRAS)
Membrane trafficking [BR:hmh04131]
 Exocytosis
  Small GTPases and associated proteins
   Other small GTPases and associated proteins
    116466571 (HRAS)
 Endocytosis
  Macropinocytosis
   Ras GTPases
    116466571 (HRAS)
Exosome [BR:hmh04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   116466571 (HRAS)
  Exosomal proteins of colorectal cancer cells
   116466571 (HRAS)
GTP-binding proteins [BR:hmh04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    116466571 (HRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N ATP_bind_1 Septin Ldh_1_N AAA_16
Other DBs
NCBI-GeneID: 116466571
NCBI-ProteinID: XP_032005161
LinkDB
Position
Unknown
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPG
CMSCKCVLS
NT seq 570 nt   +upstreamnt  +downstreamnt
atgacggaatataagctcgtggtggtgggcgccggcggtgtgggcaagagtgcgctgacc
atccagctaatccagaaccactttgtggacgaatacgaccccactatagaggactcctac
cggaagcaggtggtcattgatggggagacatgcctgttggacatcctggacacggccggc
caggaggagtacagcgccatgcgggaccagtacatgcgcaccggggagggcttcctgtgt
gtgtttgccatcaacaacaccaagtctttcgaggacatccaccagtacagggagcagatc
aaacgggtgaaggactcggacgatgtgcccatggtgctggtgggaaacaagtgtgatctg
gctgcacgcaccgtggagtctcggcaggctcaggacctcgcccgaagctacggcatcccc
tacatcgagacctcggccaagacccggcagggagtggaggatgccttctacacgttggtg
cgtgagatccggcagcacaagctgcggaagctgaaccctcctgatgagagtggccctggc
tgcatgagctgcaagtgtgtgctctcctga

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