Hylobates moloch (silvery gibbon): 116473735
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Entry
116473735 CDS
T08803
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
116473735 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
hmh03032
]
116473735 (TOP2B)
03036 Chromosome and associated proteins [BR:
hmh03036
]
116473735 (TOP2B)
Enzymes [BR:
hmh01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
116473735 (TOP2B)
DNA replication proteins [BR:
hmh03032
]
Eukaryotic type
DNA Topoisomerases
116473735 (TOP2B)
Chromosome and associated proteins [BR:
hmh03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
116473735 (TOP2B)
Centrosome formation proteins
Centriole proteins
116473735 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
116473735
NCBI-ProteinID:
XP_032018167
LinkDB
All DBs
Position
Unknown
AA seq
1626 aa
AA seq
DB search
MAKSGGCGAGAGVGGGSGALTWVTLFDQNNAAKKEESETANKNDSSKKLSVERVYQKKTQ
LEHILLRPDTYIGSVEPLTQFMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRD
KNMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVT
GGRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITF
QPDLSKFKMEKLDKDIVALMTRRAYDLAGSCRGVKVMFNGKKLPVNGFRSYVDLYVKDKL
DETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIE
VVKKKNKAGVSVKPFQVKNHIWIFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFF
KAASNCGIVESILNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLIL
TEGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYK
KSYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVK
ASKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFR
YAGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFI
NKELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHH
GEQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFP
AVDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRM
LDGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQV
LEPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNS
MVLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKI
QGKITIENRSKKDLIQMLVQRGYESDPVKAWKEAQEKAAEEDETQNQHDDSSSDSGTPSG
PDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVE
SQEREDILAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKK
KKGDLDTAAVKVEFDEEFSGAPVEGAGEEASTPSAPINKGPKPKREKKEPGTRVRKTPTS
SGKPSAKKMKKRNPWSDDESKSESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDD
DADDDDDDNNDLEELKVKASPITNDGEDEFVPSDGLDKDEYTFSPGKSKATPEKSLHDKK
SQDFGNLFSFPSYSQKSEDDSAKFDSNEEDSASVFSPSFGLKQTDKVPSKTVAAKKGKPS
SDTAPKPKRAPKQKKVVEAVNSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNP
GRKTSKTTSKKPKKTSFDQDSDVDIFPSDFPTEPPSLPRTGRARKEVKYFAESDEEEEDV
DFAMFN
NT seq
4881 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtcgggtggctgcggcgcgggagccggcgtgggcggcggcagcggggcactg
acctgggtgactctttttgatcagaacaatgctgcaaaaaaagaagagtcagaaactgcc
aacaaaaatgattcttcaaagaagttgtctgttgagagagtgtatcagaagaagacacaa
cttgaacacattcttcttcgtcctgatacatatattgggtcagtggagccattgacgcag
ttcatgtgggtatatgatgaagatgtaggaatgaattgcagagaggttacctttgtgcca
ggtttatacaagatctttgatgaaattttggttaatgctgctgacaataaacagagggat
aagaacatgacttgtattaaagtttctattgatcctgaatctaacattataagcatttgg
aataatgggaaaggcattccagtagtagaacacaaggtagagaaagtttatgttcctgct
ttaatttttggacagcttttaacatccagtaactatgatgatgatgagaaaaaagttaca
ggtggtcgtaatggttatggtgcaaaactttgtaatattttcagtacaaagtttacagta
gaaacagcttgcaaagaatacaaacacagttttaagcagacatggatgaataatatgatg
aagacttctgaagccaaaattaaacattttgatggtgaagattacacatgcataacattc
caaccagatctgtccaaatttaagatggaaaaacttgacaaggatattgtggccctcatg
actagaagggcatatgatttggctggttcatgtagaggggtcaaggtcatgtttaatgga
aagaaattgcctgtaaatggatttcgcagttacgtagatctttatgtgaaagacaaattg
gatgaaactggggtggccctgaaagttattcatgagcttgcaaatgaaagatgggatgtt
tgtctcacattgagtgaaaaaggattccagcaaatcagctttgtaaatagtattgcaact
acaaaaggtggacggcacgtggattatgtggtagatcaagttgttggtaaactgattgaa
gtagttaagaaaaagaacaaagctggtgtatcagtgaaaccatttcaagtaaaaaaccat
atatggatttttattaattgccttattgaaaatccaacttttgattctcagactaaggaa
aacatgaccctgcagcccaaaagttttgggtctaaatgccagctgtcagaaaaatttttt
aaagcagcctctaattgtggcattgtagaaagtatcctgaactgggtgaaatttaaggct
cagactcagctgaataagaagtgttcatcagtaaaatacagtaaaatcaaaggtattccc
aaactggatgacgctaatgatgctggtggtaaacattccctggagtgtacactgatatta
acagagggagactctgccaaatcactggctgtgtctggattaggtgtgattggacgagac
agatacggagtttttccactcaggggcaaaattcttaatgtacgggaagcttctcataaa
cagatcatggaaaatgctgaaataaataatattattaaaatagttggtctacaatataag
aaaagttatgatgatgcagaatctctgaaaactttacgctatggaaagattatgattatg
actgatcaggatcaagatggttctcacataaaaggcctgcttattaatttcatccatcac
aattggccatcacttttgaagcatggttttctcgaagagttcattactcctattgtaaag
gcaagcaaaaataagcaggaactttccttctacagtattcctgaatttgatgaatggaaa
aaacatatagaaaaccagaaagcctggaaaataaagtactataaaggattgggtactagt
acagctaaagaagcaaaggagtattttgctgatatggaaaggcatcgcatcttgtttaga
tatgctggtcctgaagatgatgctgccattaccttggcatttagtaagaagaagattgat
gacagaaaagaatggttaacaaattttatggaagaccggagacagcgtaggctacatggc
ttaccagagcaatttttatatggtactgcaacaaagcatttgacttataatgatttcatc
aacaaggaattgattctcttctcaaactcagacaatgaaagatctataccatctcttgtt
gatggctttaaacctggccagcggaaagttttatttacctgtttcaagaggaatgataaa
cgtgaagtaaaagttgcccagttggctggatctgttgctgagatgtcggcttatcatcat
ggagaacaagcattgatgatgactattgtgaatttggctcagaactttgtgggaagtaac
aacattaacttgcttcagcctattggtcagtttggaactcggcttcatggtggcaaagat
gctgcaagcccccgttatattttcacaatgttaagctctttagcaaggctactttttcct
gctgtggatgacaacctccttaagttcctttatgatgataatcaacgtgtagagcctgag
tggtatatacctataattcccatggttttaataaatggtgctgagggcattggtactgga
tgggcttgtaaactacccaactatgatgctagggaaattgtgaacaatgtcagacgaatg
ctagatggcctggatcctcatcccatgcttccaaactacaaaaactttaaaggcacgatt
caagaacttggtcaaaaccagtatgcagtcagtggtgaaatatttgtagtggacagaaac
acagtagaaattacagagcttccagttagaacttggacacaggtatataaagaacaggtt
ttagaacctatgctaaatgggacagacaaaacaccagcattaatttctgattataaagaa
tatcatactgacacaactgtgaaatttgtggtgaaaatgactgaagagaaactagcacaa
gcagaagctgctggactgcataaagtttttaaacttcaaactactcttacttgtaattcc
atggtactctttgatcatatgggatgtctgaagaaatatgaaactgtgcaagacattctg
aaagaattctttgatttacgattaagttattatggtttacgtaaggagtggcttgtggga
atgttgggagcagaatctacaaagcttaacaatcaagcccgtttcattttagagaagata
caagggaaaattactatagagaataggtcaaagaaagatttgattcaaatgttagtccag
agaggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcagaa
gaggatgaaacacaaaaccagcatgatgatagttcctccgattcaggaactccttcaggc
ccagattttaattatattttaaatatgtctctgtggtctcttactaaagaaaaagttgaa
gaactgattaaacagagagatgcaaaagggcgagaggtcaatgatcttaaaagaaaatct
ccttcagatctttggaaagaagatttagcagcatttgttgaagaactggataaagtggaa
tctcaagaacgagaagatattctggctggaatgtctggaaaagcaattaaaggtaaagtt
ggcaaacctaaggtgaagaaactccaactggaagagacaatgccctcaccttatggcaga
agaataattcctgaaattacagctatgaaggcagatgccagcaaaaagttgctgaagaag
aagaagggtgatcttgatactgcagcagtaaaagtggaatttgatgaagaattcagtgga
gcgccagtagaaggtgcaggagaagaggcgtcgactccgtcagctcctataaataaaggc
cccaaacccaaaagggagaagaaggagcctggtaccagagtgagaaaaacacctacatca
tctggtaaacctagtgcaaagaaaatgaagaaacggaatccttggtcagatgatgaatcc
aagtcagaaagtgatttggaagaaacagaacctgtggttattccaagagattctttgctt
aggagagcagcagccgaaagacctaaatacacatttgatttctcagaagaagaggatgat
gatgctgatgatgatgatgatgacaataatgatttagaggaattgaaagttaaagcatct
cccataacaaatgatggggaagatgaatttgttccttcagatgggttagataaagatgaa
tatacattttcaccaggcaaatcaaaagccactccagaaaaatctttgcatgacaaaaaa
agtcaggattttggaaatctcttctcatttccttcatattctcagaagtcagaagatgat
tcagctaaatttgacagtaatgaagaagattctgcttctgttttttcaccatcatttggt
ctgaaacagacagataaagttccaagtaaaacagtagctgctaaaaagggaaaaccgtct
tcagatacagcccctaagcccaagagagccccaaaacagaagaaagtagtagaggctgta
aactctgactcagattcagaatttggtattccaaagaagactacaacaccaaaaggtaaa
ggccgaggggcaaagaaaaggaaagcatctggctctgaaaatgaaggcgattataaccct
ggcaggaaaacatccaaaacaacaagcaagaaaccgaagaaaacatcttttgatcaggat
tcagatgtggacatcttcccctcagacttccctactgagccaccttctctgccacgaacc
ggtcgggctaggaaagaagtaaaatattttgcagagtctgatgaagaagaagaagacgtt
gattttgcaatgtttaattaa
DBGET
integrated database retrieval system
