Hylobates moloch (silvery gibbon): 116475593 Help Entry 116475593         CDS       T08803                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 isoform X1   KO K10160   toll-like receptor 4 Organism hmh  Hylobates moloch (silvery gibbon) Pathway hmh04064   NF-kappa B signaling pathway hmh04066   HIF-1 signaling pathway hmh04145   Phagosome hmh04151   PI3K-Akt signaling pathway hmh04217   Necroptosis hmh04613   Neutrophil extracellular trap formation hmh04620   Toll-like receptor signaling pathway hmh04621   NOD-like receptor signaling pathway hmh04936   Alcoholic liver disease hmh05132   Salmonella infection hmh05133   Pertussis hmh05134   Legionellosis hmh05135   Yersinia infection hmh05140   Leishmaniasis hmh05142   Chagas disease hmh05144   Malaria hmh05145   Toxoplasmosis hmh05146   Amoebiasis hmh05152   Tuberculosis hmh05161   Hepatitis B hmh05162   Measles hmh05164   Influenza A hmh05170   Human immunodeficiency virus 1 infection hmh05171   Coronavirus disease - COVID-19 hmh05205   Proteoglycans in cancer hmh05235   PD-L1 expression and PD-1 checkpoint pathway in cancer hmh05321   Inflammatory bowel disease hmh05323   Rheumatoid arthritis hmh05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:hmh00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     116475593 (TLR4)    04066 HIF-1 signaling pathway     116475593 (TLR4)    04151 PI3K-Akt signaling pathway     116475593 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     116475593 (TLR4)   09143 Cell growth and death    04217 Necroptosis     116475593 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     116475593 (TLR4)    04620 Toll-like receptor signaling pathway     116475593 (TLR4)    04621 NOD-like receptor signaling pathway     116475593 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     116475593 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     116475593 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     116475593 (TLR4)    05161 Hepatitis B     116475593 (TLR4)    05171 Coronavirus disease - COVID-19     116475593 (TLR4)    05164 Influenza A     116475593 (TLR4)    05162 Measles     116475593 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     116475593 (TLR4)    05135 Yersinia infection     116475593 (TLR4)    05133 Pertussis     116475593 (TLR4)    05134 Legionellosis     116475593 (TLR4)    05152 Tuberculosis     116475593 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     116475593 (TLR4)    05144 Malaria     116475593 (TLR4)    05145 Toxoplasmosis     116475593 (TLR4)    05140 Leishmaniasis     116475593 (TLR4)    05142 Chagas disease     116475593 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     116475593 (TLR4)    05321 Inflammatory bowel disease     116475593 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     116475593 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     116475593 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:hmh04131]     116475593 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:hmh04054]     116475593 (TLR4)    04090 CD molecules [BR:hmh04090]     116475593 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:hmh00536]     116475593 (TLR4) Membrane trafficking [BR:hmh04131]  Endocytosis   Phagocytosis    Toll-like receptors     116475593 (TLR4) Pattern recognition receptors [BR:hmh04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    116475593 (TLR4) CD molecules [BR:hmh04090]  Proteins   116475593 (TLR4) Glycosaminoglycan binding proteins [BR:hmh00536]  Hyaluronan   Cell surface receptors    116475593 (TLR4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 TIR LRR_4 LRR_14 LRR_1 TIR_2 LRR_9 LRR_5 LRR_Zer-1 LRR_6 LRR_EndoS LRR_R13L1-DRL21 ThsB_TIR Curto_V2 Pentapeptide_4 Motif Other DBs NCBI-GeneID:  116475593 NCBI-ProteinID:  XP_032020873 LinkDB All DBs Position Unknown AA seq 832 aa AA seqDB search MMSASRLAGTLIPAMAFLSCVRPESWDPCVEVVPNITYQCMELNFYKIPDNLPFSTKNLD LSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSLLSTLILTGNPIQSLALG AFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHL DLSSNKIQSIYCKDLQVLHQMPLLNLSLDLSLNPMNFIQPGAFKEISLHKLTLRNNFDSL NVMKTCIQGLAGLEVHRLVLGEFRNEGNLEEFDKSALEGLCNLTIEEFRLAYLDHYLDDI IDLFNCLANVSSFSLVSVTIKRVEDFSYNFGWQHLELVNCKFGQFPTLNLKSLKRLTFTA NRGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTNSLKYLDLSFNDVITMSSNFLG LEQLEHLDLQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSNLEVLKMAG NSFQENFLPDIFTELRNLTFLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPY KCLNSLQVLDYSLNHIMTSKKQELQRFPSSLAFLNLTQNDFACTCEHESFLQWIKDQRQL LVEVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVLSVLVVSVVAVLVYKFYFHLML LAGCMKYGRGENTYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAA NIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLR QQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCN NT seq 2499 nt NT seq  +upstreamnt  +downstreamnt atgatgtctgcctcgcgcctggctgggactctgatcccagccatggccttcctctcctgc gtgagaccagaaagttgggatccctgcgtggaggtggttcctaacattacttatcaatgc atggagctgaatttctacaaaatccccgacaacctccccttctcaaccaagaacctggac ctgagctttaatcccctgaggcatttaggcagctatagcttcttcagtttcccagaactg caggtgctggatttatccaggtgtgaaatccagacaattgaagatggggcatatcagagc ctaagcctcctctccaccttaatattgacaggaaaccccatccagagtttagctctggga gccttttctggactatcaagtttacagaagctagtggctgtggagacaaatctagcatct ctagagaacttccccattggacatctcaaaactttgaaagaacttaatgtggctcacaat cttatccaatctttcaaattacctgagtatttttctaatctgaccaatctagagcacttg gacctttccagcaacaagattcaaagtatttattgcaaagacttgcaggttctacatcaa atgcccctactcaatctctctttagacctgtccctgaaccctatgaactttatccaacca ggtgcatttaaagaaattagccttcataagctgactttaagaaataattttgatagttta aatgtaatgaaaacttgtattcaaggtctggctggtttagaagtccatcgtttggttctg ggagaatttagaaatgaaggaaacttggaagagtttgacaaatctgctctagagggcctg tgcaatttgaccattgaagaattccgattagcatacttagaccactacctcgatgatatt attgacttatttaattgtttggcaaatgtttcttcattttccctggtgagtgtgactatt aaaagggtagaagacttttcttataatttcggatggcaacatttagaattagttaactgt aaatttggacagtttcccacattgaacctcaaatctctcaaaaggcttactttcactgcc aacagaggtgggaatgctttttcagaagttgatctaccaagccttgagtttctagatctc agtagaaatggcttgagtttcaaaggttgctgttctcaaagtgattttgggacaaacagc ctaaagtatttagatctgagcttcaatgatgttattaccatgagttcaaacttcttgggc ttagaacagctagaacatctggatttgcagcattccaatttgaaacaaatgagtgagttt tcagtattcctatcactcagaaacctcatttaccttgacatttctcatactcacaccaga gttgctttcaatggcatcttcaatggcttgtccaatctcgaagtcttgaaaatggctggc aattctttccaggaaaacttccttccagatatcttcacagagttgagaaacttgaccttc ctggacctctctcagtgtcaactggagcaattgtctccaacagcatttaactcactctcc agtcttcaggtactaaatatgagccacaacaacttcttttcattggatacgtttccttat aagtgtctgaactccctccaggttcttgattacagtctcaatcacataatgacttccaaa aaacaggaactacagcgttttccaagtagtctagccttcttaaatcttactcagaatgac tttgcttgtacttgtgaacacgagagtttcctgcagtggatcaaggaccagaggcagctc ttggtggaagttgaacgaatggaatgtgcaacaccttcagataagcagggcatgcctgtg ctgagtttgaatatcacctgtcagatgaataagaccatcattggtgtgtcagtcctcagt gtgcttgtagtatctgttgtagcagttctggtctataagttctattttcacctgatgctt cttgctggctgcatgaagtatggtagaggtgaaaacacctatgatgcctttgttatctac tcaagccaggatgaggactgggtaaggaatgagctagtaaagaatttagaagaaggggtg cctccctttcagctctgccttcactacagagactttattcccggtgtggccattgctgcc aacatcatccatgaaggtttccataaaagccgaaaggtgattgttgtggtgtcccagcac ttcatccagagccgctggtgtatctttgagtatgagattgctcagacctggcagtttctg agcagtcgtgctgggatcatcttcattgtcctgcagaaggtggagaagaccctgctcagg cagcaggtggagctgtaccgccttctcagcaggaacacttacctggagtgggaggatagt gtcctggggcggcacatcttctggagacgactcagaaaagccctgctggatggtaaatca tggaatccagaaggaacagtgggtacaggatgcaattag

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