Hylobates moloch (silvery gibbon): 116475694
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Entry
116475694 CDS
T08803
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh00790
Folate biosynthesis
hmh01100
Metabolic pathways
hmh01240
Biosynthesis of cofactors
hmh01523
Antifolate resistance
hmh04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
116475694 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
116475694 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
116475694 (FPGS)
Enzymes [BR:
hmh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
116475694 (FPGS)
BRITE hierarchy
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Paralog
GFIT
Motif
Pfam:
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
116475694
NCBI-ProteinID:
XP_032021094
LinkDB
All DBs
Position
Unknown
AA seq
587 aa
AA seq
DB search
MSRARSHLRAALFLAAASARGVTTQVAARRGLSAWPVPQEPSMEYQDAVRMLNTLQTNAG
YLEQVKRQRGDPQTQLEAMERYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
WQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPTLEALEEGGPPLTLGLEGE
HQRSNAALALQLAHCWLQRQDCHGAGEPKASRPGLLWQLPLAPVFQPTSHMRLGLRNTEW
PGRTQVLRRGPLTWYLDGAHTASSVQACVRWFRQALQGRERPSGGPEVRVLLFNATGDRD
PAALLKLLQPCQFDYAVFCPNLTEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLDEE
QASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWISQGRDPIFQPPSP
PKGLLTHAVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcgcggagccacctgcgcgccgctctgttcctggcagcggcgtctgcgcgc
ggcgtaacgacccaggtcgcggcgcggcggggcttgagcgcgtggccggtgccgcaggag
cccagcatggagtaccaggatgctgtgcgcatgctcaataccctgcagaccaatgccggc
tacctggagcaggtgaagcgccagcggggtgacccccagacacagctggaagccatggaa
cggtacctggcacggagtgggctgcaggtggaggacttggaccggctgaacatcatccat
gtcactgggacgaaggggaagggctccacctgtgccttcacggaatgtatcctccgaagc
tatggcctgaagacaggattctttagctctccccacctggtgcaggttcgggagcggatc
cgcatcaatgggcagcccatcagtcctgagctcttcaccaagtacttctggcgcctctac
caccggctggaggagaccaaggatggcagctgtgtctccatgcccccctacttccgcttc
ctgacactcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtggag
gtgggcattggcggggcttatgactgcaccaacatcatcaggaagcctgtggtgtgcgga
gtctcctctcttggcatcgaccacaccagcctcctgggggatacggtggagaagatcgca
tggcagaaagggggtatctttaagcaaggtgtccctgccttcactgtactccaacctgaa
ggtcccctggcagtgctgagggaccgagcccagcagatctcatgtcctctatacctgtgt
ccgacgctggaggccctggaggaaggggggccgccgctgaccctgggcctggagggggag
caccagcggtccaacgccgccttggccttgcagctggcccactgctggctgcagcggcag
gactgccatggtgctggggagccgaaggcatccaggccagggctcctgtggcagctgccc
ctggcacccgtgttccagcccacatcccacatgcggcttgggcttcgtaacacagagtgg
ccgggccggacgcaggtgctgcggcgcgggcccctcacctggtacctggacggcgcgcac
accgccagcagcgtgcaggcctgcgtgcgctggttccgccaagcgctgcagggccgcgag
aggcccagcggtggcccagaggttcgagtcttgctcttcaatgctaccggggaccgggac
ccggcggccctgctgaagctgctgcagccctgccagtttgactatgccgtcttctgccct
aacctgacagaggtgtcatccacaggcaacgcagaccaacagaacttcacggtgacactg
gaccaggttctgctccgctgcctggaacaccagcagcactggaaccacctggacgaagag
caggccagcccggacctctggagtgcccccagcccagagcctggtgggtccgcatccctg
cttctggcgccccacccaccccacacctgcagtgccagttccctcgtcttcagctgcatt
tcacatgccttgcaatggatcagccaaggccgagaccccatcttccagccacccagtccc
ccaaagggcctcctcacccacgccgtggctcacagtggagccagcatactccgtgaggct
gctgccatccatgtgctagtcactggcagcctgcacctggtgggtggtgtcctgaagctg
ctggagcccgcactgtcccagtag
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