KEGG   Hylobates moloch (silvery gibbon): 116475873
Entry
116475873         CDS       T08803                                 
Symbol
NOTCH1
Name
(RefSeq) neurogenic locus notch homolog protein 1 isoform X1
  KO
K02599  Notch 1
Organism
hmh  Hylobates moloch (silvery gibbon)
Pathway
hmh01522  Endocrine resistance
hmh04330  Notch signaling pathway
hmh04658  Th1 and Th2 cell differentiation
hmh04919  Thyroid hormone signaling pathway
hmh05020  Prion disease
hmh05165  Human papillomavirus infection
hmh05200  Pathways in cancer
hmh05206  MicroRNAs in cancer
hmh05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:hmh00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    116475873 (NOTCH1)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    116475873 (NOTCH1)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    116475873 (NOTCH1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    116475873 (NOTCH1)
   05206 MicroRNAs in cancer
    116475873 (NOTCH1)
  09162 Cancer: specific types
   05224 Breast cancer
    116475873 (NOTCH1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    116475873 (NOTCH1)
  09164 Neurodegenerative disease
   05020 Prion disease
    116475873 (NOTCH1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    116475873 (NOTCH1)
SSDB
Motif
Pfam: EGF hEGF EGF_TEN EGF_CA EGF_2 Ank_2 Ank NOD Notch NODP Ank_4 Ank_5 Ank_3 EGF_3
Other DBs
NCBI-GeneID: 116475873
NCBI-ProteinID: XP_032021578
LinkDB
Position
Unknown
AA seq 2556 aa
MPPLLAPLLCLALLPALAARGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDP
NPCLSTPCKNAGTCHVVDRGGVADYACSCPLGFSGPLCLTPLDNACLTNPCRNGGTCDLL
TLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVN
ECGQNPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVT
HECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQ
LMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCE
CPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGA
NPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMP
GYEGVHCEVNTDECASSPCLHNGHCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNG
AKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHC
ETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKID
GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNEC
NSNPCVHGACWDSLNGYKCNCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCR
EGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRN
GGECRGSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGSYRCHCQAGYS
GRNCETDIDDCRPNPCHNGGSCTDGVNTAFCDCLPGFQGTFCEEDINECASDPCHNGANC
TDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQH
DVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQ
YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGS
YCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGMNCSEEIDECLSHPCQNGGTCLD
LPNTYKCSCPRGTQGVHCEINVDDCNPLVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV
GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGG
TCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTG
PECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDI
PPPQIEEACELPECKEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYF
SDGRCDSQCNSAGCLFDGFDCQHAEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLD
CAEHVPERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAHGQQMIFPYY
GREEELRKHPIKRAAEGWAAPDALLGQVKASLLPGGSGGGRRRRELDPMDVRGSIVYLEI
DNRQCVQASSQCFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPAQLHFMYVA
AAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNA
SDGALMDDNQNEWGDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRMSAMAP
TPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASL
HNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQIL
IRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNN
VDAAVVLLKNGANKDMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDI
AQERMHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSPPLCSPNGYLGSLKPGVQGKKVRK
PSSKGLACGSKEAKDLKARRKKAQDGKGCLLDSSGMLSPVDSLESPHGYLSDVASPPLLP
SPFQQSPSVPLNHLPGMPDTHLGIGHLNVAAKPEMAALGGGGRLAFETGPPRLSHLPVAS
GTSTVLGSSSGGAMNFTVGGSTSLNGQCEWLSRLQSGMVPNQYNPLRGSVAPGPLSTQAP
SLQHGMVGPLHSSLAASALSQMMSYQGLPSTRLATQPHLVQTQQVQPQNLQMQQQNLQPP
NIQQQQSLQPPPPPPQPHLGVSSAASSHLGRSFLGGDPSQADVQPLGPSSLAVHTILPQE
SPALPTSLPSSLVPPVTAAQFLTPPSQHSYSSSPVDNTPSHQLQVPEHPFLTPSPESPDQ
WSSSSPHSNVSDWSEGVSSPPTSMQSQITRIPETFK
NT seq 7671 nt   +upstreamnt  +downstreamnt
atgccgccgctcctggcgcccctgctctgcctggcgctgctgcccgcgctcgccgcacga
ggcccgcgatgctcccagcccggtgagacctgcctgaatggcgggaagtgtgaagcggcc
aatggcacggaggcctgcgtctgtggcggggccttcgtgggcccacgatgccaggaccct
aacccgtgcctcagcaccccctgcaagaacgctgggacatgccacgtggtggaccgcgga
ggcgtggcagactatgcctgcagctgtcccctgggcttctctgggcccctctgcctgaca
cccctggacaacgcctgcctcaccaacccctgccgcaacgggggcacctgcgacctgctc
acgctgacggagtacaagtgccgctgccctcccggctggtcagggaaatcgtgccagcag
gctgacccgtgtgcctccaacccctgcgccaacggtggccaatgcctgcccttcgaggcc
tcctacatctgccactgcccacccagcttccacggccccacctgccggcaggatgtcaac
gagtgcggccagaaccccgggctttgccgccacggaggcacctgccacaacgaggtcggc
tcctaccgctgcgtctgccgcgccacccacaccggccccaactgcgagcggccctacgtg
ccctgcagcccctcgccctgccagaacgggggcacctgccgccccacgggtgacgtcacc
cacgagtgtgcctgcctgccaggcttcaccggccagaactgtgaggagaatatcgacgat
tgtccaggaaacaattgcaagaacgggggcgcctgtgtggacggtgtgaacacctacaac
tgccgctgcccgccagagtggacaggtcagtactgtaccgaggatgtggacgagtgccag
ctgatgccaaatgcctgccagaacggcgggacctgccacaacacccacggtggctacaac
tgcgtgtgtgtcaacggctggactggtgaggactgcagcgagaacattgatgactgtgcc
agcgccgcctgcttccacggcgccacctgccatgaccgcgtggcctccttctactgcgag
tgtccccatggccgcacaggtctgctgtgccacctcaacgacgcgtgcatcagcaacccc
tgcaacgagggctccaactgtgacaccaaccccgtcaatggcaaggccatctgcacctgc
ccctcggggtacacgggcccggcctgcagccaggacgtggatgagtgctcgctgggtgcc
aacccctgcgagcatgcgggcaagtgcatcaacacgctgggctcctttgagtgccagtgt
ctgcagggctacacaggcccccgctgcgagatcgacgtcaacgagtgtgtctcgaacccg
tgccagaacgacgccacctgcctggaccagattggggagttccagtgcatctgcatgccc
ggctacgagggtgtgcactgcgaggtcaacacggacgagtgtgccagcagcccctgcctg
cacaacggccactgcctggacaagatcaatgagttccagtgcgagtgtcccacgggcttc
actgggcatctgtgccagtacgatgtggacgagtgtgccagcaccccctgcaagaatggt
gccaagtgcctggacggacccaacacttacacctgtgtgtgcacagaagggtacacaggg
acgcactgcgaggtggacattgatgagtgtgaccccgacccctgccactacggctcctgc
aaggacggtgtcgccaccttcacctgcctctgccgcccgggctacacgggccaccactgc
gagaccaacatcaacgagtgctctagccagccctgccgccacgggggcacctgccaggac
cgcgacaatgcctacctctgcttctgcctgaaggggaccacaggacccaactgcgagatc
aacctggatgactgtgccagcagcccctgcgactcgggcacctgtctggacaagatcgat
ggctacgagtgtgcctgtgagccgggctacacagggagcatgtgtaacatcaacatcgat
gagtgtgcgggcaacccctgccacaacgggggcacctgtgaggacggcatcaatggcttc
acctgccgctgccccgagggctaccacgaccccacctgcctgtctgaggtcaatgagtgc
aatagcaacccctgcgtccacggggcctgctgggacagcctcaacgggtacaagtgcaac
tgtgaccctgggtggagtgggaccaactgtgacatcaacaacaacgagtgtgagtccaac
ccttgtgtcaacggcggcacctgcaaagacatgaccagtggctacgtgtgcacctgccgg
gagggcttcagcggtcccaactgccagaccaacatcaacgagtgtgcatccaacccatgt
ctgaaccagggcacgtgtattgacgacgttgctgggtacaagtgcaactgcctgctgccc
tacacaggtgccacatgtgaggtggtgctggccccatgtgcccccagcccctgcagaaac
ggcggagagtgcaggggatccgaggactatgagagcttctcctgcgtctgccccacgggc
tggcaagggcagacctgtgaggtcgacatcaacgagtgtgttctgagcccgtgccgacac
ggcgcatcctgccagaacacccatggcagctaccgctgccactgccaggccggctacagc
gggcgcaactgcgagacggacattgacgactgccggcccaacccgtgtcacaacggcggc
tcctgcacagacggcgtcaacacggccttctgcgactgcctgcccggcttccagggcact
ttctgtgaggaggacatcaacgagtgtgccagtgacccctgccacaacggggccaactgc
acggactgcgtggacagctacacgtgcacctgccccgcaggcttcagcgggatccactgt
gagaacaacacgcccgactgcacagagagctcctgcttcaacggtggcacctgcgtggat
ggcatcaactcgttcacctgcctgtgtccacccggcttcacgggcagctactgccagcac
gatgtcaacgagtgcgactcacagccctgcctgcacggtggcacctgccaggacggctgc
ggctcctacagatgcacctgcccccagggctacaccggccccaactgccagaacctcgtg
cactggtgtgattcctcgccctgcaagaacggcggcaaatgctggcagacccacacccag
taccgctgcgagtgccccagcggctggaccggcctttactgtgacgtgcccagcgtgtcc
tgtgaggtggctgcgcagcgacaaggtgttgacgttgcccgcctgtgccagcatggaggg
ctctgtgtggacgcgggcaacacgcaccactgccgctgccaggcgggctacacaggcagc
tactgtgaggacctggtggacgagtgctcacccagcccctgccagaatggggccacctgc
acggactacctgggtggctactcctgcaagtgcgtggccggctaccacgggatgaactgc
tctgaggagatcgacgagtgcctgtcccacccctgccagaacgggggcacctgcctcgac
ctccccaacacctacaagtgctcctgcccacggggcacgcagggtgtgcactgtgagatc
aacgtggacgactgcaaccccctcgttgaccccgtgtcccggagccccaagtgctttaac
aacggcacctgtgtggaccaggtgggcggctacagctgcacctgcccgccgggcttcgtg
ggcgagcgctgtgagggggatgtcaacgagtgcctgtccaacccctgcgacgcccgtggc
acccagaactgcgtgcagcgcgtcaacgacttccactgcgagtgccgtgccggtcacacc
gggcgccgctgtgagtccgtcatcaacggctgcaagggcaagccctgcaagaatgggggc
acctgcgccgtggcctccaacaccgcccgcgggttcatctgcaagtgccctgcgggcttc
gagggcgccacgtgtgagaatgatgctcgtacctgcggcagcctgcgctgcctcaacggt
ggcacatgcatctccggcccgcgcagccccacctgcctgtgcctgggccccttcacaggt
cccgaatgccagttcccagccagcagcccctgcctgggcggcaacccctgctacaaccag
gggacctgtgagcccacgtccgagagccccttctaccgttgcctgtgccccgccaaattc
aacgggctcttgtgccacatcctggactacagcttcgggggcggggccgggcgcgacatc
cccccgccgcagatcgaggaggcgtgcgagctgcccgagtgcaaggaggacgcgggcaac
aaggtctgcagcctgcagtgcaacaaccacgcgtgcggctgggacggcggcgactgctcc
ctcaacttcaatgacccctggaagaactgcacacagtctctgcagtgctggaagtacttc
agcgacggccgctgtgacagccagtgcaactcggccggctgcctcttcgacggcttcgac
tgccagcacgcagaaggccagtgcaaccccctgtacgaccagtactgcaaggaccacttc
agcgatgggcactgcgaccagggctgcaacagcgcggagtgcgagtgggacgggctggat
tgtgcggagcatgtgcccgagaggctggcagccggcaccctggtggtggtggtgctgatg
ccgccggagcagctgcgcaatagctccttccatttcctgcgggagctcagccgtgtgctg
cacaccaacgtggtcttcaagcgcgacgcacacggccagcagatgatcttcccctactac
ggccgcgaggaggagctgcgcaagcaccccatcaagcgtgccgccgagggctgggccgca
cccgatgccctgctgggccaggtgaaggcctcgctgctccctggtggcagcgggggtggg
cggcggcggagggagctggaccccatggacgtccgcggctccatcgtctacctggagatt
gacaaccggcagtgtgtgcaggcctcctcgcagtgcttccagagtgccaccgacgtggcc
gcgttcctgggagcgctcgcctcgctgggcagcctcaacatcccctacaagattgaggct
gtgcagagtgagaccgtggagccgcccccgccggcgcagctgcacttcatgtacgtggcg
gcggccgcctttgtgctcctgttcttcgtgggctgcggggtgctgctgtcccgcaagcgc
cgacggcagcatggccaactctggttccctgagggcttcaaagtgtccgaggccagcaag
aagaagcggcgggagcccctcggcgaggactccgtgggcctcaagcccctgaagaacgcc
tcagacggtgccctcatggacgacaaccagaatgagtggggggacgaggacctggagacc
aagaagttccggttcgaggagcccgtggttctgcctgacctggacgaccagacagaccac
cggcagtggactcagcagcacctggatgccgctgacctgcgcatgtctgccatggccccc
acaccgccccagggcgaggttgacgccgactgcatggacgtcaatgtccgcgggcctgac
ggctttaccccgctcatgatcgcctcctgcagcgggggcggcctggagacgggcaacagc
gaggaggaggaggacgcgccggccgtcatctccgacttcatctaccagggcgccagcctg
cacaaccagacggaccgcacgggcgagactgccttgcacctggccgcccgctactcacgc
tctgatgccgccaagcgcctgctggaggccagcgcggacgccaacatccaggacaacatg
ggccgcaccccgctgcatgcggctgtgtctgccgacgcacagggtgtcttccagatcctg
atccggaaccgagccacagacttggatgcccgcatgcatgatggcacgactccgctgatc
ctggctgcccgcctggccgtggagggcatgctggaggacctcatcaactcacacgccgac
gtcaacgccgtagatgacctgggcaagtccgccctgcactgggccgccgccgtgaacaat
gtggatgccgcagttgtgctcctgaagaacggggctaacaaagacatgcagaacaacaag
gaggagacacccctgtttctggctgcccgggagggcagctacgagaccgccaaggtgctg
ctggaccactttgccaaccgggacatcacggatcatatggaccgcctgccgcgggacatc
gcgcaggagcgcatgcaccacgacatcgtgaggctgctggacgagtacaacctggtgcgc
agcccgcagctgcacggagccccgctggggggcacgcccaccctgtcgcccccgctctgc
tcgcccaacggctatctgggcagcctcaagcccggcgtgcagggcaagaaggttcgcaag
cccagcagcaaaggcctggcctgtggaagcaaggaggccaaggacctcaaggcgcggagg
aagaaggcccaggacggcaagggctgcctgctggacagctccggcatgctctcgcccgtg
gactccctggagtcaccccacggctacctgtcagacgtggcctcgccgccactgctgccc
tccccgtttcagcagtctccgtccgtgccccttaaccacctgcctggtatgcccgacacc
cacctgggcatcgggcacctgaacgtggcggccaagcccgagatggcggcgctgggtggg
ggcggccggctggccttcgagaccggcccccctcgtctctcccacctgcccgtggcctct
ggcaccagcaccgtcctgggctccagcagcggaggggccatgaatttcaccgtgggcggg
tccaccagtttgaatggtcaatgcgagtggctgtcccggctgcagagcggcatggtgccg
aaccaatacaaccctctccgggggagcgtggcaccaggtcccctgagcacgcaggccccc
tccctgcagcacggcatggtgggcccgctgcacagtagccttgctgccagcgccctgtcc
cagatgatgagctaccagggcctgcccagcacccggctggccacccagcctcacctggtg
cagacccagcaggtgcagccacaaaacttacagatgcagcagcagaacctgcagccacca
aacatccagcagcagcaaagcctgcagccaccaccaccaccaccacagccacaccttggc
gtgagctcagcagccagcagccacctgggccggagcttcctgggtggagacccgagccag
gcagacgtgcagccactgggccccagcagcctggcggtgcacactattctgccccaggag
agccccgccctgcccacatcgctgccatcctcactggtcccacctgtgaccgcagcccag
ttcctgacgcccccctcgcagcacagctactcctcctcgcctgtggacaacaccccaagc
caccagctacaggtgcctgagcaccccttcctcaccccgtcccccgagtcccctgaccag
tggtccagctcgtccccgcattccaacgtctccgactggtccgagggcgtctccagccct
cccaccagcatgcagtcccagatcacccgcattccggagaccttcaagtaa

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