Hylobates moloch (silvery gibbon): 116477657
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Entry
116477657 CDS
T08803
Symbol
POLE
Name
(RefSeq) DNA polymerase epsilon catalytic subunit A isoform X1
KO
K02324
DNA polymerase epsilon subunit 1 [EC:
2.7.7.7
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh03030
DNA replication
hmh03410
Base excision repair
hmh03420
Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09120 Genetic Information Processing
09124 Replication and repair
03030 DNA replication
116477657 (POLE)
03410 Base excision repair
116477657 (POLE)
03420 Nucleotide excision repair
116477657 (POLE)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
hmh03032
]
116477657 (POLE)
03400 DNA repair and recombination proteins [BR:
hmh03400
]
116477657 (POLE)
Enzymes [BR:
hmh01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.7 Nucleotidyltransferases
2.7.7.7 DNA-directed DNA polymerase
116477657 (POLE)
DNA replication proteins [BR:
hmh03032
]
Eukaryotic type
DNA Replication Elongation Factors
DNA polymerase epsilon complex
116477657 (POLE)
DNA repair and recombination proteins [BR:
hmh03400
]
Eukaryotic type
SSBR (single strand breaks repair)
BER (base exicision repair)
Long Patch-BER factors
DNA polymerase epsilon complex
116477657 (POLE)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DUF1744
POL2_thumb
DNA_pol_B_exo1
zf_DPOE_2
zf-DPOE
DNA_pol_B
DNA_pol_B_exo2
RNase_H_2
APP_N
Translat_reg
Motif
Other DBs
NCBI-GeneID:
116477657
NCBI-ProteinID:
XP_032024108
LinkDB
All DBs
Position
Unknown
AA seq
2281 aa
AA seq
DB search
MALRRGGQRRADPGADGEASRDDGATSSVSALKRLERSQWTDKMDLRFGFERLKEPGEKT
GWLINMHPTEILDEDKRLVSAVDYYFIQDDGSRFKVALPYKPYFYIATRKGCEREVSSFL
SKKFQGKIAKVETVPKEDLDLPNHLVGLKRNYIKLSFHTVEDLVKVRKEISPAVKKNREQ
DHASDAYTALLSSVLQRGSVITDEEETSKKIADQLDNIVDMREYDVPYHIRLSIDLKIHV
AHWYNVRYRGNAFPVEITRRDDLVERPDPVVLAFDIETTKLPLKFPDAETDQIMMISYMI
DGQGYLITNREIVSEDIEDFEFTPKPEYEGPFCVFNEPDEAHLIQRWFEHVQETKPTIMV
TYNGDFFDWPFVEARAAVHGLSMQQEIGFQKDSQGEYKAPQCIHMDCLRWVKRDSYLPVG
SHNLKAAAKAKLGYDPVELDPEDMCRMATEQPQTLATYSVSDAVATYYLYMKYVHPFIFA
LCTIIPMEPDEVLRKGSGTLCEALLMVQAFHANIIFPNKQEQEFNKLTDDGHVLDSETYV
GGHVEALESGVFRSDIPCRFRMNPAAFDFLLQRVEKTLCHAIEEEEKVPVEQVTNFEEVC
DEIKSKLASLKDVPSRIECPLIYHLDVGAMYPNIILTNRLQPSAMVDEATCAACDFNKPG
ANCQRKMAWQWRGEFMPASRSEYHRIQHQLESEKFPPLFPEGPARAFHELSREEQAKYEK
RRLADYCRKAYKKIHITKVEERLTTICQRENSFYVDTVRAFRDRRYEFKGLHKVWKKKLS
AAVEVGDAAEVKRCKNMEVLYDSLQLAHKCILNSFYGYVMRKGARWYSMEMAGIVCFTGA
NIITQARELIEQIGRPLELDTDGIWCVLPNSFPENFVFKTTNAKKPKVTISYPGAMLNIM
VKEGFTNDQYQELAEPSSLTYVTRSENSIFFEVDGPYLAMILPASKEEGKKLKKRYAVFN
EDGSLAELKGFEVKRRGELQLIKIFQSSVFEAFLKGSTLEEVYGSVAKVADYWLDVLYSK
AANMPDSELFELISENRSMSRKLEDYGEQKSTSISTAKRLAEFLGDQMVKDAGLSCRYII
SRKPEGSPVTERAIPLAIFQAEPTVRKHFLRKWLKSSSLQDFDIRAILDWDYYIERLGSA
IQKIITIPAALQQVKNPVPRVKHPDWLHKKLLEKNDVYKQKKISELFTLEGRRQVTMAEA
AEDSPRPSAPDMEDFGLVKLPHPAAPVTVKRKRVLWESQEESQDLTPTVPWQEILGQPPA
LGTTQEEWLVWLWFHKKKWQLQARQRLARRKRQRLESAEGVLRPAAIRDGPATGLGSFLR
RTARSILDLPWQIVQISETSQAGLFRLWALIGNDLHCIRLSIPRVFYVNQRVAKAEEGAS
YRKVNRVLPRSNMVYNLYEYSVPEDMYQEHINEINAELSAPDIEGVYETQVPLLFRALVH
LGCVCVVNKQLVRHLSGWEAETFALEHLEMRSLAQFSYLEPGSIRHIYLYHHAQGHKALF
GIFILSQRRASVFVLDTVRSNQMPSLGALYSAEHSLLLEKVGPELLPPPKHTFEVRAETD
LKTICRAIQRFLLAYKEERRGPTLIAVQSTWELKRLASEIPVLEEFPLVPICVADKINYG
VLDWQRHGARRMIRHYLNLDTCLSQAFEMSRYFHIPIGNLPEDISTFGSDLFFARHLQRH
NHLLWLSPTARPDLGGKEADDNCLVMEFDDQATVEINSSGCYSTVCVELDLQNLAVNTIL
QSHHVNDMEGADSMGISFDVIQQASLEDMITGGQAASAPASYDETALCSNTFRILKSMVV
GWVKEITQYHNIYADNQVMHFYRWLRSPSSLLHDPALHRTLHNMMKKLFLQLIAEFKRLG
SSVIYANFNRIILCTKKRRVEDAIAYVEYITSSIHSKEIFHSLTISFSRCWEFLLWMDPS
NYGGIKGKVSSRIHCGLQDSQKAGGAEDEQENEDDGEEEEEVEESNVEDLLENNWNILQF
LPQAASCQNYFLMIVSAYIVAVYHCMKDGLRRSAPGSTPVRRRGASQLSQEAEGAAGALP
GMITFSQDYVANELTQSFFTITQKIQKKVTGSRNSTELSEMFPVLPGSHLLLNNPALEFI
KYVCKVLSLDTNITNQVNKLNRDLLRLVDVGEFSEEAQFRDPCCSYVLPEVICRSCNFCR
DLDLCKDSSFSEDGAVLPQWLCSNCQAPYDSSAIEMMLVEVLQKKLMAFTLQDLVCLKCR
GVKETSMPVYCSCAGDFALTIHTQVFMEQIRIFRNIAQHYGMSYLLETLEWLLQKNPQLG
R
NT seq
6846 nt
NT seq
+upstream
nt +downstream
nt
atggctctgagaagaggcgggcagcggcgcgcggacccaggcgcggacggcgaggccagc
agggatgatggtgccacttcctcagtctcggcactcaagcgcctggaacggagtcagtgg
acggataagatggatttgcggtttggttttgagcggctgaaggagcctggtgagaagaca
ggctggctcattaacatgcatcctaccgagattttagatgaagataagcgcttagtcagt
gcagtggattactactttattcaagatgacggaagcagatttaaggtggccttgccctat
aaaccgtatttctacattgcaactagaaagggttgtgagcgagaagtttcatcttttctc
tccaagaagtttcagggcaaaattgcaaaagtggagactgtccccaaagaggatctagac
ttgccaaatcacttggtgggtttgaagcgaaattacatcaagctgtccttccacactgtg
gaggatcttgtcaaagtgaggaaggagatctcccctgctgtgaagaagaacagggagcag
gatcatgccagcgacgcgtacacagctctgctttccagtgttctgcagaggggcagtgtc
attactgatgaagaggaaacctctaagaagatagctgaccagttggacaacattgtggac
atgcgcgagtacgatgttccctaccacatccgcctctccattgacctgaagatccacgtg
gctcattggtacaatgtcagataccgaggaaatgcttttccggtagaaatcacccgccga
gatgaccttgttgaacgacctgaccctgtggttttggcatttgacattgagacgaccaaa
ctgccccttaagtttcctgatgctgagacagaccagattatgatgatttcctacatgatt
gatggccagggctacctcatcaccaacagggagattgtttcagaagatattgaagatttt
gagttcacccccaagccagaatatgaaggccccttttgtgtcttcaatgaacccgatgag
gctcatctgatccaaaggtggtttgaacacgtccaggagaccaaacctaccatcatggtc
acctacaacggggacttttttgactggccatttgtggaggctcgggcagcagtccacggt
ctgagcatgcagcaggagataggcttccaaaaggacagccagggggagtacaaggcaccc
cagtgcatccacatggactgcctcaggtgggtgaagagggacagttaccttcctgtgggc
agtcacaatctcaaggcggccgccaaggccaagctaggctatgatcccgtggagctagat
ccagaggacatgtgccggatggccaccgagcagccccagactctggccacgtattctgtg
tcagatgctgtcgccacttactacctgtacatgaagtacgtccacccatttatcttcgct
ctgtgcaccattattcccatggagcccgatgaggtgctgcggaagggctctggcacgctg
tgtgaggccttgctgatggtgcaggccttccacgccaacatcatcttccccaacaagcaa
gagcaggagttcaataagctgacggacgacggacacgtgctggactctgagacctacgtc
gggggccacgtggaggccctggagtctggggtcttccgcagcgatatcccttgccgattt
aggatgaatcctgccgcctttgacttcctgctgcagcgggttgagaagaccttgtgccac
gccattgaggaagaggagaaggtgcctgtggagcaagtcaccaactttgaagaggtgtgt
gatgagattaagagcaagcttgcctccctgaaggacgttcccagccgcatcgagtgtcca
ctcatctaccacctggacgtgggagccatgtaccccaacatcatcctgaccaaccgcctg
cagccctctgccatggtggacgaagccacctgtgctgcctgtgacttcaataagcctgga
gcaaactgccagcggaagatggcctggcagtggaggggcgaattcatgccagccagtcgc
agcgaataccatcggatccagcaccaactggagtcagagaagttcccccccttgttccca
gaggggccagctcgggcctttcatgaactgtcccgtgaggaacaggcaaaatacgagaag
agaaggctggcggattactgccggaaagcctacaagaagatccacatcaccaaggtggaa
gagcgtctcaccaccatctgccagcgggaaaactccttctacgtggacaccgtacgtgcc
ttccgggacagacgttacgagttcaaagggctccacaaggtgtggaaaaagaagctctcg
gcggctgtggaggtgggcgacgcggctgaggtgaagcgctgcaagaacatggaggtgctg
tatgactcgctgcagctggcccacaagtgcatcctgaactctttctatggctacgtcatg
cgcaagggggctcgctggtactccatggagatggctggcatcgtctgcttcacaggggcc
aacatcatcacccaggcacgggagctgatcgagcagattgggaggcccttagagctggac
acagatggaatatggtgcgtcctacccaacagcttcccagaaaattttgtcttcaagacg
accaacgcgaagaagcccaaagtgaccatctcctacccaggcgccatgttgaacatcatg
gtcaaggaaggcttcaccaatgaccagtaccaggagctggctgagccgtcctcactcacc
tacgtcacccgctcagagaacagcatcttttttgaggttgatgggccctaccttgccatg
attcttccagcctccaaggaagaaggcaagaaattgaagaagagatatgctgtgttcaat
gaagatggttctctggctgagctcaagggctttgaggtcaaacgccgcggggaactgcag
ctgattaagatcttccaatcctcggtgtttgaggccttcctcaagggcagcacgctggaa
gaggtgtatggctctgtagccaaggtggctgactactggctggacgtgctgtacagcaag
gcagccaacatgcctgactctgagctattcgagctcatctctgagaatcgttctatgtct
cggaaactggaagattacggggagcagaagtctacatccatcagcacagcaaagcgcctg
gccgagttcctgggagaccagatggtcaaggatgcagggctgagttgccgctacatcatc
tcccgcaagcccgagggctcccccgtcacggagagggccatcccacttgccattttccaa
gcagagcccacggtgaggaagcactttctccggaaatggctcaagagctcttcccttcaa
gactttgatattcgagcaattctggattgggactactacattgagcggctgggaagcgcc
atccagaagatcatcaccatccctgcagccctgcagcaggtaaagaacccagtgccacgt
gtcaaacaccctgactggctgcacaaaaaactgctggagaagaatgatgtctataagcag
aagaagatcagtgagctcttcaccctggagggcagaagacaggtcacgatggccgaggcc
gcagaagacagtccgaggccaagtgctcccgacatggaggacttcggcctcgtgaagctg
cctcacccagcagcccctgtcactgtgaagaggaagcgagttctttgggagagtcaggag
gagtcccaggacctcacgccgactgtgccctggcaggaaatcttggggcagcctcccgcc
ctgggaaccacccaggaggagtggcttgtctggctctggttccacaagaagaagtggcag
ctgcaggcccggcagcgcctcgcccgcaggaagaggcagcgtctggagtcggcagagggt
gtgctgaggcccgcggccatccgggatggtcctgccacggggctggggagcttcttgcga
agaactgcccgcagcatcctggaccttccgtggcagattgtgcagatcagcgagaccagc
caggccggcctgttcaggctgtgggcgctcattggcaatgacttgcattgcatcaggctg
agcatcccccgtgtgttctacgtgaaccagcgagtggctaaagcggaggagggtgcttcg
tatcgcaaggtaaatcgggtccttcctcgctccaacatggtctacaatctctatgagtat
tcagtgccagaggacatgtaccaggaacacatcaacgagatcaacgctgagctgtcagcg
ccagacatcgagggcgtatatgagactcaggttccgttactgttccgggccctggtgcac
ctgggctgtgtgtgtgtggtcaataaacagctggtgaggcacctttcgggctgggaagca
gagacctttgctcttgagcacctggagatgcgctctctggcccagttcagctacctggaa
ccagggagtatccgccatatctacttgtaccaccacgcacagggccacaaagcgctcttc
gggatcttcatcctctcacagcgcagggcatccgtctttgtgctggacactgtgcgcagc
aaccagatgcccagccttggcgccctgtactcagcagagcacagcctcctcctggagaag
gtgggccctgagctcctgccacccccgaaacacaccttcgaagttcgggcagaaactgac
ctgaagaccatctgcagagccatccaacgattcctgctcgcctacaaggaggagcgccgg
gggcccacactcatcgctgttcagtccacctgggagctgaagaggctggccagtgagatt
cccgtcttggaggaattcccactggtgcctatctgtgtggccgacaagatcaactatggg
gtcctggactggcagcgccatggagcccggcgcatgatccggcactacctcaacctggac
acctgcttgtcgcaggccttcgagatgagcaggtactttcacattcccatcgggaacctg
ccagaggacatctccacattcggctccgacctcttctttgcccgccacctccagcgccac
aaccacctgctctggctgtcccctacggcccgccctgacctgggtggaaaggaggctgat
gacaactgtcttgtcatggagttcgatgaccaagccactgttgagatcaacagttcaggc
tgttactccacagtgtgtgtggagctggaccttcagaacctggccgtcaacaccattctc
cagtctcaccatgtcaacgacatggagggggccgacagtatggggatcagcttcgacgtg
atccagcaggcctccctagaggacatgatcacgggtggtcaggctgccagtgccccggcc
agctacgatgagacagccctgtgctctaacaccttcaggatcctgaagagcatggtcgtg
ggctgggtgaaggagatcacccagtaccacaacatctacgcagacaaccaggtgatgcac
ttctaccgctggcttcggtcgccatcctctctgcttcatgaccccgccctgcaccgcaca
ctccacaacatgatgaagaagctcttcctgcagctcatcgctgagttcaagcgcctgggg
tcgtcagtcatctatgccaacttcaaccgcatcatcctctgtacaaagaagcgccgtgtg
gaagatgccatcgcttacgtggagtacatcaccagcagcatccattcaaaggagatcttc
cattctttgacaatttctttctctcgatgctgggaatttcttctctggatggatccatct
aactatggcggaatcaaaggaaaagtttcatctcgtattcactgtggactgcaagactcc
cagaaagcagggggagcagaggatgagcaggaaaatgaggatgatggggaggaggaggaa
gaggtggaggaatccaacgtggaggatttattggaaaacaattggaacattttgcagttt
ttgccacaggcagcctcctgccagaactacttcctcatgattgtttcagcatacattgtg
gccgtgtaccactgcatgaaggatgggctgagacgcagtgctccaggaagcacccccgtg
aggaggaggggggccagccagctctcccaggaggccgagggggcggccggagcccttccc
ggaatgatcaccttctctcaggattatgtcgcaaatgaactcactcagagcttcttcacc
atcactcagaagattcagaagaaagtcacaggctctcggaactccactgagctctcggag
atgtttcctgtgctccccggttcccacttgctgctcaataaccctgctctggagttcatc
aaatacgtgtgcaaggtgctgtccctggacaccaacatcacaaaccaggtgaataagctg
aaccgagacctgcttcgcctggtggatgtcggtgagttctccgaggaggcccagttccga
gacccctgctgctcctacgtgcttcctgaggtcatctgccgcagctgtaacttctgccgc
gacctggacctgtgtaaagactcttccttctcagaggatggggcggtcctgcctcagtgg
ctctgctccaactgccaggcgccctacgactcctctgccatcgagatgatgctggtggaa
gttctacagaagaagctgatggccttcaccctgcaggacctggtctgtctgaagtgccgc
ggggtgaaggagaccagcatgcctgtgtactgcagctgcgcgggggacttcgccctcacc
atccacacccaggtcttcatggaacagatcagaatcttccggaacattgcccagcactac
ggcatgtcgtacctcctggagaccctggagtggctgctgcagaagaacccacagctgggc
cgttag
DBGET
integrated database retrieval system
