Hylobates moloch (silvery gibbon): 116478444
Help
Entry
116478444 CDS
T08803
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh04217
Necroptosis
hmh04380
Osteoclast differentiation
hmh04620
Toll-like receptor signaling pathway
hmh04621
NOD-like receptor signaling pathway
hmh04630
JAK-STAT signaling pathway
hmh04658
Th1 and Th2 cell differentiation
hmh04659
Th17 cell differentiation
hmh05145
Toxoplasmosis
hmh05160
Hepatitis C
hmh05161
Hepatitis B
hmh05162
Measles
hmh05164
Influenza A
hmh05165
Human papillomavirus infection
hmh05167
Kaposi sarcoma-associated herpesvirus infection
hmh05168
Herpes simplex virus 1 infection
hmh05169
Epstein-Barr virus infection
hmh05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
116478444 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
116478444 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
116478444 (TYK2)
04621 NOD-like receptor signaling pathway
116478444 (TYK2)
04658 Th1 and Th2 cell differentiation
116478444 (TYK2)
04659 Th17 cell differentiation
116478444 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
116478444 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
116478444 (TYK2)
05160 Hepatitis C
116478444 (TYK2)
05171 Coronavirus disease - COVID-19
116478444 (TYK2)
05164 Influenza A
116478444 (TYK2)
05162 Measles
116478444 (TYK2)
05168 Herpes simplex virus 1 infection
116478444 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
116478444 (TYK2)
05169 Epstein-Barr virus infection
116478444 (TYK2)
05165 Human papillomavirus infection
116478444 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
116478444 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hmh01001
]
116478444 (TYK2)
Enzymes [BR:
hmh01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
116478444 (TYK2)
Protein kinases [BR:
hmh01001
]
Non-receptor tyrosine kinases
JAK family [OT]
116478444 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
116478444
NCBI-ProteinID:
XP_032025527
LinkDB
All DBs
Position
Unknown
AA seq
1202 aa
AA seq
DB search
MPAEPPARSMPLRHWGTARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSEPSL
TAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDSSLMLYFRIRFYFRN
WHGMNPQEPAVYRCGPPGTEASSDHTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELS
SEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTR
LRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPC
YIRDSGEAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVQEEVNKEEVSKASSGSSGRNLQ
ASLSGKKAKAHKAVGQPADRPREPLWAYFCDFRDITHVVLKERSVSIHRQDNKCLELSLP
SRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED
GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQNGAFVLEGWGRSFPSVRE
LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARTSTRTFNLSQLSFHRVDQKE
ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH
HDIALAFYETASLMSQVSHAHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM
AWKMMVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS
REERVERIPWMAPECLPGGPNSLSTAMDKWGFGATLLEICFDGEAPLQSRNPSEKEHFYQ
RQHRLPEPSCPELATLTSQCLTYEPTQRPSFRTILRDLTRLQPHTLPDLADVMTVNPDSL
ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVALKALKADCGPQHRLGWK
QEIDILRTLYHEHIVKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQ
QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV
FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGVAQGQMTVLRLT
ELLERGERLPRPNKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS
VC
NT seq
3609 nt
NT seq
+upstream
nt +downstream
nt
atgcctgctgagccacctgccaggagcatgcctctgcgccactgggggacggccaggggc
agcaagcctgttggggatggagcccagcccatggctgccatggggggcctgaaggtgctt
ctgcactgggctggtccaggcggtggggagccctgggtcactttcagtgagccatcgctg
acagctgaggaagtctgcatccacattgcacataaagttggtatcactcctccttgtttc
aatctcttcgccctcttcgatgctcaagcccaagtctggttgcccccaaaccacatcctg
gagatccccagagactcaagtctgatgctatatttccgcataaggttttatttccggaac
tggcatggcatgaatcctcaggaaccggctgtgtaccgttgtgggcccccaggaaccgag
gcatcctcagatcacacagcacaggggatgcaactcctggacccagcctcatttgagtac
ctctttgagcagggcaagcatgagtttgtgaatgacgtggcatcactgtgggagctgtcg
agcgaggaggagatccaccactttaagaatgagagcctgggcatggcctttctgcacctc
tgtcacctcgctctccgccatggcatccccctggaggaggtggccaagaagaccagcttc
aaggactgcatcccgcgctccttccgtcggcatatccggcagcacagcgccctgacccgg
ctgcgccttcggaacgtcttccgcaggttcctgcgggacttccagccgggccgactctcc
cagcagatggtcatggtcaaatacctagccacactcgagcggctggcaccccgcttcggc
acagagcgtgtgcccgtgtgccacctgaggctgctggcccaggccgagggggagccctgc
tacatcagggacagtggggaggcccctacagaccctggccctgagtctgctgctgggccc
ccaacccacgaggtgctggtgacaggcactggtggcatccagtggtggccagtacaggag
gaggtgaacaaggaggaggtgagcaaggcttctagtggtagcagtggcaggaacctccaa
gccagcctgtctgggaagaaggccaaggctcacaaggcagttggccagccggcggacagg
ccgcgggagccactgtgggcctacttctgcgacttccgggacatcacccacgtggtgctg
aaagagcgcagtgtcagcatccaccggcaggacaacaagtgcctggagctgagtctgcct
tcccgggctgcggcgctgtccttcgtgtcgctggtggacggctatttccgcctgacggct
gactccagccactacctgtgccatgaggtggctcccccacggctggtgatgagcatccgg
gatgggatccatggacctctgctggagccatttgtgcaggccaagctgcggcctgaggac
ggcctgtacctcattcactggagcaccagccacccctaccgcctgatcctcacagtggcc
cagcgtagccaggcaccagacggcatgcagagcttgcggctccggaagttccccattgag
cagcagaacggggccttcgtgctggagggctggggccggtccttccccagcgttcgggaa
cttggggctgccttgcagggctgcttgctgagggccggggatgactgcttctctctgcgt
cgctgttgcctgccccaaccaggagaaacctccaatctcatcatcatgcggggggctcgg
accagcaccaggacattcaacctcagccagctcagcttccaccgggttgaccagaaggag
atcacccagctgtcccacttgggccagggcacaaggaccaatgtgtatgagggccgcctg
cgagtggagggcagcggggaccctgaggagggcaagatggatgacgaggaccccctcgtg
cctggcagggaccgtgggcaggagctacgagtggtgctcaaagtgctggaccctagtcac
catgacattgccctggccttctacgagacagccagcctcatgagccaggtctcccatgcg
cacctggccttcgtgcatggcgtctgtgtgcgcggtcctgaaaatatcatggtgacagag
tacgtggagcacggacccctggatgtgtggttgcggagggagcgcggccatgtgcccatg
gcttggaagatgatggtggcccagcagctggccagtgccctcagctacctggagaacaag
aaccttgttcatggtaatgtgtgtggccggaacatcctgctggcccggctggggctggca
gagggcaccagccccttcatcaagctgagtgatcccggcgtgggcctgggcgccctctcc
agggaggagcgggtggagaggatcccctggatggcccccgaatgcctaccaggtgggccc
aacagcctaagcaccgccatggacaagtgggggtttggcgccaccctcctggagatctgc
tttgacggagaggcccctctgcagagccgcaacccctccgagaaggagcatttctaccag
aggcagcaccggctgcctgagccctcctgcccagagctggccacactcaccagccagtgt
ctgacctatgagccaacccagaggccatcattccgcaccatcctgcgtgatctcacccgg
ctgcagccccacactcttccagatcttgctgacgtcatgactgtgaacccagactcactg
gcgtcagaccctacggttttccacaagcgctatttgaaaaagatccgagatctgggcgag
ggtcacttcggcaaggtcagcttgtactgctacgatccgaccaacgacggcactggcgag
atggtggcgctgaaagccctcaaggcagactgcggcccccagcaccgcttgggctggaag
caggagattgacattctgcgcacgctctatcacgagcacatcgtcaagtacaagggctgc
tgcgaggaccaaggcgagaagtcgctgcagctggtcatggagtacgtgcccctgggcagc
ctccgagactacctgccccggcacagcgtcgggctggcccagctgctgctcttcgcccag
cagatctgcgagggcatggcctatctgcacgcgcagcactacatccaccgagacctagcc
gcgcgcaacgtgcttctggacaacgacaggctggtcaagatcggggactttggcctagcc
aaagccgtgcccgaaggccacgagtactaccgcgtgcgcgaggatggggacagccccgtg
ttctggtatgccccagagtgcctgaaggagtataagttctactatgcgtccgatgtctgg
tcgttcggggtgaccctgtatgagctgctgacgcactgtgactccagccagagcccccct
acgaaattccttgagctcataggcgttgctcagggtcagatgacagttctgagactcacc
gagttgctggaacgaggggagaggctgccacggcccaacaaatgtccctgtgaggtctat
catctcatgaagaactgctgggagacagaggcatccttccgcccaacctttgagaacctc
atacccatcctgaagacagtccatgagaagtaccaaggccaggctccttcagtgttcagc
gtgtgctga
DBGET
integrated database retrieval system
