Hylobates moloch (silvery gibbon): 116482110
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Entry
116482110 CDS
T08803
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X4
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh01521
EGFR tyrosine kinase inhibitor resistance
hmh01522
Endocrine resistance
hmh04010
MAPK signaling pathway
hmh04014
Ras signaling pathway
hmh04015
Rap1 signaling pathway
hmh04066
HIF-1 signaling pathway
hmh04068
FoxO signaling pathway
hmh04081
Hormone signaling
hmh04114
Oocyte meiosis
hmh04140
Autophagy - animal
hmh04144
Endocytosis
hmh04150
mTOR signaling pathway
hmh04151
PI3K-Akt signaling pathway
hmh04152
AMPK signaling pathway
hmh04211
Longevity regulating pathway
hmh04213
Longevity regulating pathway - multiple species
hmh04510
Focal adhesion
hmh04520
Adherens junction
hmh04550
Signaling pathways regulating pluripotency of stem cells
hmh04730
Long-term depression
hmh04913
Ovarian steroidogenesis
hmh04914
Progesterone-mediated oocyte maturation
hmh05200
Pathways in cancer
hmh05202
Transcriptional misregulation in cancer
hmh05205
Proteoglycans in cancer
hmh05214
Glioma
hmh05215
Prostate cancer
hmh05218
Melanoma
hmh05224
Breast cancer
hmh05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
116482110 (IGF1R)
04014 Ras signaling pathway
116482110 (IGF1R)
04015 Rap1 signaling pathway
116482110 (IGF1R)
04066 HIF-1 signaling pathway
116482110 (IGF1R)
04068 FoxO signaling pathway
116482110 (IGF1R)
04151 PI3K-Akt signaling pathway
116482110 (IGF1R)
04152 AMPK signaling pathway
116482110 (IGF1R)
04150 mTOR signaling pathway
116482110 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
116482110 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
116482110 (IGF1R)
04140 Autophagy - animal
116482110 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
116482110 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
116482110 (IGF1R)
04520 Adherens junction
116482110 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
116482110 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
116482110 (IGF1R)
04914 Progesterone-mediated oocyte maturation
116482110 (IGF1R)
09156 Nervous system
04730 Long-term depression
116482110 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
116482110 (IGF1R)
04213 Longevity regulating pathway - multiple species
116482110 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
116482110 (IGF1R)
05202 Transcriptional misregulation in cancer
116482110 (IGF1R)
05205 Proteoglycans in cancer
116482110 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
116482110 (IGF1R)
05214 Glioma
116482110 (IGF1R)
05218 Melanoma
116482110 (IGF1R)
05215 Prostate cancer
116482110 (IGF1R)
05224 Breast cancer
116482110 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
116482110 (IGF1R)
01522 Endocrine resistance
116482110 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hmh01001
]
116482110 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
hmh04090
]
116482110 (IGF1R)
Enzymes [BR:
hmh01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
116482110 (IGF1R)
Protein kinases [BR:
hmh01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
116482110 (IGF1R)
CD molecules [BR:
hmh04090
]
Proteins
116482110 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
116482110
NCBI-ProteinID:
XP_032031190
LinkDB
All DBs
Position
Unknown
AA seq
1367 aa
AA seq
DB search
MKAGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRH
NYCSKDKIPIRKYADGTIDIEEITENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVMQVANSTTSSRSRNTTAADAYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
EPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVQAKTGYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRH
SGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgaaggctggctccggaggagggtccccgacctcgctgtgggggctcctgtttctctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtgggccaggcatcgacatccgc
aacgactatcagcagctgaagcgcctggagaactgcacggtgatcgagggctacctccac
atcctgctcatctccaaggctgaggactaccgcagctaccgcttccccaagctcacggtc
attaccgagtacttgctgctgttccgagtggctggcctcgagagccttggagacctcttc
cccaacctcacggtcatccgcggctggaaactcttctacaactacgccctggtcatcttc
gagatgaccaatctcaaggatattgggctttacaacctgaggaacattactcggggggcc
atcaggattgagaaaaatgctgacctctgttacctctccactgtggactggtccctgatc
ctggatgcggtgtccaataactacattgtggggaataagcccccaaaggaatgtggggac
ctgtgtccagggaccatggaggagaagccgatgtgtgagaagaccaccatcaacaatgag
tacaactaccgctgctggaccacaaaccgctgccagaaaatgtgcccgagcgcgtgtggg
aagcgggcatgcaccgagaacaacgagtgctgccaccccgagtgcctgggcagctgcagc
gcgcctgacaacgacacggcctgcgtagcttgccgccactactactacgccggtgtctgc
gtgcctgcctgcccgcccaacacctacaggtttgagggctggcgctgtgtggaccgtgac
ttctgcgccaacatcctcagcgccgagagcagcgactccgagggatttgtgatccacgac
ggcgagtgcatgcaggagtgcccctcgggcttcatccgcaacggcagccagagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgtgaggaagaaaagaaaacaaagacc
attgattctgttacttctgctcagatgctccaaggatgcaccatcttcaagggcaatttg
ctcatcaacatccgccgggggaataacattgcttcagaactggagaacttcatggggctc
atcgaggtggtgacgggctacgtgaagatccgccattctcatgccttggtctccttgtcc
ttcctaaaaaaccttcgcctcatcttaggagaggagcagctagaagggaattactccttc
tacgtccttgacaaccagaacttgcagcaactgtgggactgggaccaccgcaacctgacc
atcaaagcagggaaaatgtactttgctttcaatcccaaattatgtgtttctgaaatttac
cgcatggaggaagtgacggggactaaagggcgccaaagcaaaggggacataaacaccagg
aacaacggggagagagcctcctgtgaaagtgacgtcctgcatttcacctccaccaccacg
tggaagaatcgcatcatcataacctggcaccggtaccggccccctgactacagggatctc
atcagcttcaccgtttactacaaggaagcaccctttaagaatgtcacggagtatgatggg
caggacgcctgcggctccaacagctggaacatggtggacgtggacctcccgcccaacaag
gacgtggagcccggcatcttactgcatgggctgaagccctggactcagtacgccgtttac
gtcaaggctgtgaccctcaccatggtggagaacgaccatatccgtggggccaagagtgag
atcttgtacattcgcaccaatgcttcagttccttccattcccttggacgttctttcagcg
tcgaactcctcttctcagttaatcgtgaagtggaaccctccctctctgcccaacggcaac
ctgagttactacattgtgcgctggcagcggcagcctcaggacggctacctttaccggcac
aattactgctcgaaagacaaaatccccatcaggaagtatgccgacggcaccatcgacatt
gaggagatcacagagaaccccaagactgaggtgtgtggtggagagaaaggaccttgctgc
gcctgccccaaaactgaagccgagaagcaggccgagaaggaggaggctgagtaccgcaaa
gtctttgagaatttcctgcacaactccatcttcgtgcccagacctgaaaggaagcggaga
gacgtcatgcaagtggccaacagcaccacgtccagccgcagcaggaacaccacggccgcc
gacgcctacaacatcaccgacccggaggagctggagacagagtaccctttctttgagagc
agagtggataacaaggagagaactgtcatttccaaccttcggcctttcacattgtaccgc
atcgatatccacagctgcaaccacgaggctgagaagctgggctgcagcgcctccaacttc
gtctttgcaaggacgatgcctgcggaaggagcagatgacattcctgggccagtgacctgg
gagccaaggcctgaaaactccatctttttaaagtggccggaacctgagaatcccaatgga
ttgattctaatgtatgaaataaaatacggatcacaagttgaggatcagcgagaatgtgtg
tccagacaggaatacaggaagtatggaggggccaagctaaaccggctaaacccggggaac
tacacagcccggattcaggccacatctctctctgggaatgggtcgtggacagatcctgtg
ttcttctatgtccaggccaaaacaggatatgaaaacttcatccatctgatcatcgctctg
cccgtcgctgtcctgttgatcgtgggagggttggtgattatgctgtacgtcttccacaga
aagagaaataacagcaggctggggaatggagtgctgtatgcctctgtgaacccggagtac
ttcagcgctgcggatgtgtacgttcctgatgagtgggaggtggctcgggagaagatcacc
atgagccgggaacttgggcaggggtcgtttgggatggtctatgaaggagttgccaagggt
gtggtgaaagacgaacctgaaaccagagtggccattaaaacagtgaacgaggccgcaagc
atgcgtgaaaggatcgagtttctcaacgaagcttctgtgatgaaggagttcaattgtcac
catgtggtgcgattgctgggtgtggtgtcccaaggccagccaacactggtcatcatggaa
ctgatgacacggggcgatctcaaaagttatctgcggtctctgaggccagaaatggagaat
aatccagtcctagcacctccaagcctaagcaagatgattcagatggccggagagattgca
gacggcatggcatacctcaacgccaacaaattcgtccacagagaccttgctgcccggaat
tgcatggtagccgaagatttcacagtcaaaatcggagattttggtatgacacgagatatc
tatgagacagactattaccggaaaggagggaaagggctgctgcctgtgcgctggatgtct
cccgagtccctcaaggatggagtcttcaccacttactcggacgtctggtccttcggggtc
gtcctctgggagatcgccacactggccgagcagccctaccagggcttgtccaatgagcag
gtccttcgcttcgtcatggagggcggccttctggacaagcccgacaactgtcctgacatg
ctgtttgaactgatgcgtatgtgctggcagtataaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaagacgagatggagcctggcttccgggaggtctccttctac
tacagcgaggagaacaagctgcccgagccggaggagctggacctggagccagagaacatg
gagagcgtccccctggacccctcggcctcctcgtcctccctgccactgcccgacagacac
tcaggacacaaggccgagaatggccccggccctggagtgctggtcctccgcgccagcttc
gacgagagacagccttacgcacacatgaacgggggccgcaagaacgagcgggccttgccg
ctgccccagtcttcaacctgctga
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integrated database retrieval system
