Hylobates moloch (silvery gibbon): 116482425
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Entry
116482425 CDS
T08803
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
hmh
Hylobates moloch (silvery gibbon)
Pathway
hmh00230
Purine metabolism
hmh00670
One carbon pool by folate
hmh01100
Metabolic pathways
hmh01523
Antifolate resistance
Module
hmh_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
hmh00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
116482425 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
116482425 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
116482425 (GART)
Enzymes [BR:
hmh01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
116482425 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
116482425 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
116482425 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
ATP-grasp_4
Dala_Dala_lig_C
ATP-grasp_3
Sacchrp_dh_NADP
DiatomPyrShell
RimK
LUD_dom
Motif
Other DBs
NCBI-GeneID:
116482425
NCBI-ProteinID:
XP_058283171
LinkDB
All DBs
Position
Unknown
AA seq
981 aa
AA seq
DB search
MAARVLIIGSGGREHTLAWKLAQSHHVKQVLVAPGNAGTACSEKISNTAISVSDHTALAQ
FCKEEKIEFVVVGPEAPLAAGIVGNLMSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TAQWKAFTKPEEACSFILSADFPALVVKASGLAAGKGVIVAKSKEEACKAVQEIMQEKAF
GAAGETIVIEELLDGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDGGPNTGGMGAYCPAP
QVSNDLLLKIKDTILQRTVDGMQQEGTPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGMLCTSLPVWLENHTALTVVMASKGYPGDYTKGVEITGFPEA
QALELEVFHAGTALKNGKVVTHGGRVLAVTAIRENLISALEEAKKGLAAINFEGAIYRKD
IGFRAIAFLQQPSPTGCKVDLGGFAGLFDLKAAGFKDPLLASGTDGVGTKLKIAQLCNKH
DTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLSVTEAVVAGIAKACGKAGCALLGG
ETAEMPDMYPPGEYDLAGFAVGAMERDQKLPHLERITEGDDVVGIASSGLHSNGFSLVRK
IVAKSSLQYSSPAPDGCGDQTLGDLLLTPTRIYSHSLLPVLRSGHVKAFAHITGGGLLEN
IPRVLPEKLGVDLDAQTWRIPKVFSWLQQEGHLSEEEMARTFNCGVGAVLVVSKEQTEQI
LRDIQQHKEEAWVIGSVVARAEGSPRVKVKNLIESMQINGSVLKNGSLTNHFSFEKKKAR
VAVLISGTGSNLQALIDSTREPNSSAQIDIVISNKAAVAGLDKAERAGIPTRVINHKLYK
NRVEFDSAIDLVLEEFSIDIVCLAGFMRILSGPFVRKWNGKMLNIHPSLLPSFKGSNAHE
QALETGVTVTGCTVHFVAEDVDAGQIILQEAVPVKRDDTVATLSERVKLAEHKIFPAALQ
LVASGTVQLGENGKICWVKEE
NT seq
2946 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagtacttataattggcagtggaggaagggaacatacgttggcctggaaa
cttgcacagtctcatcatgtcaaacaagtgttggttgccccaggaaacgcaggcactgcc
tgctctgaaaagatttcaaataccgctatctcagtcagtgaccacactgcccttgctcaa
ttctgcaaagaggagaaaattgaatttgtagttgttggaccagaagcacctctggctgct
gggattgttgggaacctgatgtctgcaggagtgcgatgctttggcccaacagcagaagcg
gctcagttagagtccagcaaaaggtttgccaaagagtttatggacagacatggaatccca
actgcacaatggaaggctttcaccaaacctgaagaggcctgcagcttcattttgagtgca
gacttccctgctttggtggtgaaggccagtggtcttgcagctggaaaaggggtgattgtt
gcaaagagcaaagaagaggcctgcaaagctgtacaagagatcatgcaggagaaagccttt
ggggcagctggagaaacaattgttattgaagaacttcttgacggagaagaggtgtcttgt
ctgtgtttcactgatggcaggactgtggcccccatgcccccagcacaggaccataagcga
ttactggagggagatggcggccctaacacagggggaatgggagcctattgtcccgcccct
caggtttctaatgatctattactaaaaattaaagatactattcttcagaggacagtggat
ggcatgcagcaagagggtactccatatacaggtattctctatgctggaataatgctgacc
aaggatggcccaaaagttctagagtttaattgccgttttggtgatccagagtgccaagta
atcctcccacttcttaaaagtgatctttatgaagtgattcagtccaccttagatggaatg
ctctgcacatctctgcccgtttggctagaaaaccacaccgccctaactgttgtcatggca
agtaaaggttaccctggagactacaccaagggtgtagagataacagggtttcctgaggct
caagctctagaactggaggtgttccacgcaggcactgccctcaaaaatggcaaagtagta
actcatgggggtagagttcttgcagtcacagccatccgggaaaatctcatatcagccctc
gaggaagccaagaaaggactagctgctataaactttgagggagcaatttataggaaagac
atcggctttcgtgccatagctttcctccagcagcccagtccaacaggctgtaaagttgat
cttggaggttttgctggtctttttgatttaaaagcagctggtttcaaagatccccttctg
gcctctggaacagatggcgttggaactaaactaaagattgcccagctgtgcaataaacat
gataccattggtcaagatttggtagcaatgtgtgttaatgatattctggcacaaggagca
gagcccctgttcttccttgattacttttcctgtggaaaacttgacctcagtgtaactgaa
gctgttgttgctggaattgccaaagcttgtggaaaagctggatgtgctctccttggaggt
gaaacagcagaaatgcctgacatgtatccacctggagagtatgacctagctgggtttgcc
gttggtgccatggagcgagatcagaaactccctcacctagaaagaatcactgagggtgat
gatgttgttggaatagcttcatctggtcttcatagcaatggatttagccttgtgaggaaa
atcgtggcaaaatcttccctccagtactcctctccagcgcctgatggttgtggtgaccag
actttaggggacttacttctcacacctaccagaatctacagccattcactgttacccgtc
ctacgttcaggacatgtcaaagcctttgcccatattactggtggaggattactagagaac
atccccagagtcctccctgagaaacttggggtagatttagatgcccagacctggaggatc
cccaaggtcttctcatggttacagcaggaaggacacctctctgaggaagagatggccaga
acatttaactgtggggttggcgctgtccttgtggtatcaaaggagcagacagagcagatt
ctgagggatatccagcagcacaaggaagaagcctgggtgattggcagtgtggttgcacga
gctgaaggttccccacgtgtgaaagtcaagaatctgattgaaagcatgcaaataaatggg
tcagtgttgaagaatggctccctgacaaatcatttctcttttgaaaaaaaaaaggccaga
gtggctgtcttaatatctggaacaggatcgaacctgcaagcactcatagacagtactcgg
gaaccaaatagttctgcacaaatcgatattgttatctccaacaaagccgcagtagctggg
ttagataaagcggaaagagctggtattcccactagagtaattaatcataaattgtataaa
aatcgtgtagaatttgacagtgcaattgacctagtccttgaagagttctccatagacata
gtctgtcttgcaggattcatgagaattctttctggcccctttgtccgaaagtggaatgga
aaaatgctcaatatccacccatccttgctcccttcttttaagggttcgaatgcccatgag
caagccctggaaaccggagtcacagttactgggtgcactgtacattttgtagctgaagat
gtagacgctgggcaaattattttgcaagaagctgttcccgtgaagagggatgatactgtc
gcaactctttctgaaagagtaaaactagcagaacataaaatatttcctgcagcccttcag
ctggtggccagtggaactgtacagcttggagaaaatggcaagatctgttgggttaaagag
gaatga
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