KEGG   Hylobates moloch (silvery gibbon): 116483711
Entry
116483711         CDS       T08803                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6 isoform X1
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
hmh  Hylobates moloch (silvery gibbon)
Pathway
hmh04010  MAPK signaling pathway
hmh04015  Rap1 signaling pathway
hmh04218  Cellular senescence
hmh04380  Osteoclast differentiation
hmh04620  Toll-like receptor signaling pathway
hmh04664  Fc epsilon RI signaling pathway
hmh04668  TNF signaling pathway
hmh04750  Inflammatory mediator regulation of TRP channels
hmh04912  GnRH signaling pathway
hmh04935  Growth hormone synthesis, secretion and action
hmh04936  Alcoholic liver disease
hmh05014  Amyotrophic lateral sclerosis
hmh05022  Pathways of neurodegeneration - multiple diseases
hmh05132  Salmonella infection
hmh05135  Yersinia infection
hmh05145  Toxoplasmosis
hmh05161  Hepatitis B
hmh05163  Human cytomegalovirus infection
hmh05167  Kaposi sarcoma-associated herpesvirus infection
hmh05169  Epstein-Barr virus infection
hmh05170  Human immunodeficiency virus 1 infection
hmh05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
hmh05417  Lipid and atherosclerosis
hmh05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:hmh00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    116483711 (MAP2K6)
   04015 Rap1 signaling pathway
    116483711 (MAP2K6)
   04668 TNF signaling pathway
    116483711 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    116483711 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    116483711 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    116483711 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    116483711 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    116483711 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    116483711 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    116483711 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    116483711 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    116483711 (MAP2K6)
   05161 Hepatitis B
    116483711 (MAP2K6)
   05163 Human cytomegalovirus infection
    116483711 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    116483711 (MAP2K6)
   05169 Epstein-Barr virus infection
    116483711 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    116483711 (MAP2K6)
   05135 Yersinia infection
    116483711 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    116483711 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    116483711 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    116483711 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    116483711 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    116483711 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    116483711 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hmh01001]
    116483711 (MAP2K6)
Enzymes [BR:hmh01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     116483711 (MAP2K6)
Protein kinases [BR:hmh01001]
 Serine/threonine kinases: STE group
  STE7 family
   116483711 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Haspin_kinase Choline_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 116483711
NCBI-ProteinID: XP_032033849
LinkDB
Position
Unknown
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIMELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINALGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSAEFVDFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKGTDVASFVKLILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggtcttaaaattccaaaagaagcattt
gaacaacctcagaccagttccacaccacctcgagatttagactccaaggcttgcatttct
attggaaatcagaactttgaggtgaaggcagatgacctggagcctataatggaactggga
cgaggtgcgtacggggtggtggagaagatgcggcacgtgcccagcgggcagatcatggca
gtgaagcggatccgagccacagtaaatagccaggaacagaaacggctactgatggatttg
gatatttccatgaggacggtggactgtccattcaccgtcactttttatggcgcactgttt
cgggagggtgatgtgtggatctgcatggagctcatggatacatcactagataaattctac
aaacaagttattgataaaggccagacaattccagaggacatcttagggaaaatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctgtctgtcattcacagagacgtc
aagccttctaatgtactcattaatgccctcggtcaagtgaagatgtgcgattttggaatc
agtggctacttggtggactctgttgctaaaacaattgatgcaggttgcaaaccatacatg
gcccctgaaagaataaacccagagctcaaccagaagggatacagtgtgaagtctgacatt
tggagtctgggcatcacgatgattgagttggccatccttcgatttccctatgattcatgg
ggaactccatttcagcagctcaaacaggtggtagaggagccatcaccacaactcccagca
gacaagttctctgcagagtttgttgactttacctcacagtgcttaaagaagaattccaaa
gaacggcctacatacccagagctaatgcaacatccatttttcaccctacatgaatccaaa
ggaacagatgtggcatcttttgtaaaactgattcttggagactaa

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