Haematobacter massiliensis: HmaOT1_10975
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Entry
HmaOT1_10975 CDS
T05861
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hml
Haematobacter massiliensis
Pathway
hml00300
Lysine biosynthesis
hml00550
Peptidoglycan biosynthesis
hml01100
Metabolic pathways
hml01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hml00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HmaOT1_10975 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HmaOT1_10975 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HmaOT1_10975 (murF)
Enzymes [BR:
hml01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HmaOT1_10975 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QBJ24728
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Position
complement(1899875..1901314)
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AA seq
479 aa
AA seq
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MTPLWTSEEAARATGGTVTQNWAATGVAIDTRELLPGDLFVALRDMRDGHDFVAEALRKG
AAAALVSRVPEGVAQDAPLLIVPDVLRGLEDLGRAARDRSTARVIGVTGSVGKTSTKEML
RAILSGQGRVHAAVRSFNNHWGVPLTLARMPADSDFAVIEIGMNHPGEIAPLARLARPDV
ALITTVAPAHLEAFDSLEAIAVEKASILDGLEPGGHVLLPGDLAVTPILKQRAQGLATTL
FGATPSCDWQLLETRITDSATSSRALAKGRTILFRVRSAGRHFAMNGLAALAAADALGLD
LTMAILDLGRWVPPEGRGLRERILLDVVDDRMAFDLIDDAFNSNPASLGAALDLLAATEP
KDGPGRFVKGRRVAILGDMLELGPQELEMHRQIAAHPAMTTLNIVHCVGPRMRALHAALP
REKRGEWHETAESLLPRLRHLIDAGDVVLVKGSKGIKLPPVVEALRRLGTPEAQAAGGE
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgaccccgctctggacatccgaggaggcggcccgcgctacgggtggcacggtcacgcag
aactgggcggccaccggggtcgccatcgatacgcgcgagcttcttcccggcgacctgttc
gtcgcgctgcgtgacatgcgcgacggccatgatttcgtggcggaagcgctccgaaaaggg
gcggcggcggcgctcgtctcccgtgtgccggagggggtcgcgcaggacgcgcccttgctc
attgtcccggatgtgctccggggtctggaagacctcgggcgtgcggcgcgcgaccgcagc
acggcacgcgttatcggcgtcaccggctctgtcggcaaaacctcaaccaaggagatgctg
cgagcgattctttccggtcagggacgggtccatgcggcggtgcggagcttcaacaaccac
tggggcgtaccgctcacccttgcccggatgcctgcggacagcgacttcgccgtcatcgaa
atcggcatgaaccatccgggtgagatcgcgccccttgcccgtcttgcccgtcctgatgtc
gcgttgatcacgaccgtggcgcctgcgcatctggaggcattcgactcgctggaggccatc
gcggtcgaaaaagcctcgatcctcgacggtctggaaccggggggacatgtgctgttgccg
ggggatctggccgtcacaccgatcctcaaacaacgggctcagggtttggcgacaaccttg
tttggcgcgacgccctcctgtgactggcagcttctcgaaacgagaatcaccgatagcgcg
acctcttctcgcgcgctggcgaaagggcggacgatcctgtttcgcgtgcgctcggcaggg
cggcatttcgcgatgaacgggcttgcggcgcttgccgccgccgacgcgctcggtctggac
ctgacgatggcgattctcgatctgggtcgctgggtgccgccggaagggcgcggtctgcgc
gagcgcatcctgctggatgtcgtcgatgaccgcatggccttcgatctgatagacgacgcc
ttcaactccaaccccgcctcgctgggtgcggcgctggacctgctggccgcgacagagccg
aaggacgggcctggccgctttgtgaagggccgccgggtggctatcctcggcgacatgctc
gaactcggcccgcaggagctggagatgcatcggcagattgccgcgcatccggccatgacg
accctcaacatcgtgcattgcgtcggccctcggatgcgggcacttcatgccgcgctgccg
cgagagaaacgcggtgaatggcatgaaacggcggagagccttcttccccgccttcgccat
ctgatcgacgcaggagatgttgtgctggtgaaaggttccaaggggatcaagctccccccc
gtggtggaggcgctgcgccgtctcggcacgcccgaagctcaggcggcgggaggggaatag
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