Heliomicrobium modesticaldum: HM1_1519
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Entry
HM1_1519 CDS
T00653
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein, putative
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
hmo
Heliomicrobium modesticaldum
Pathway
hmo00290
Valine, leucine and isoleucine biosynthesis
hmo00620
Pyruvate metabolism
hmo01100
Metabolic pathways
hmo01110
Biosynthesis of secondary metabolites
hmo01210
2-Oxocarboxylic acid metabolism
hmo01230
Biosynthesis of amino acids
Module
hmo_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
hmo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
HM1_1519
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HM1_1519
Enzymes [BR:
hmo01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
HM1_1519
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
ABZ84091
UniProt:
B0TCR5
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All DBs
Position
1525713..1527308
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AA seq
531 aa
AA seq
DB search
MDRVFIYDTTLRDGTQGEGISLSVEDKVKIAARLDQLGVAYIEGGWPGSNPKDMEFFQRA
QQMTWKHAKIAAFGSTCRPGSEACDDPNLRALIESGAPVVTIFGKSWDFHVTAALRTTLE
ENLRLVRDSITFLKNQGREVIFDAEHFYDGYKGNPAYAKEVVMTAEKAGADWIVLCDTNG
GTLPHDVLSITQEMVFTLRAPVGVHVHNDGDLAVANSIMGVMAGARQVQGTMNGYGERCG
NVNLCSVIPNLQLKMKMECLPEGKLQTLTDAAHFVGEIANMPLRNDMPFVGHSAFAHKGG
IHVSALMKDPGTYEHIQPEAVGNHRRVLVSELSGMSNVIYKAKELGLDVNRQNADTKQII
EQIKNLEHQGFQFEGAEASFEVLLRRAFGEDPVPFVLDSIRLIIEKRSDADFTSEAMIKL
RVGDQVVHTAAEGNGPVNAVDNALRKALLSHYPFLAECHLTDYKVRVLDGKDATEAKVRV
LIETRDSHDAWGTVGVSTNIIEASWQALMDSFLYGYMRERARASIESSRPA
NT seq
1596 nt
NT seq
+upstream
nt +downstream
nt
atggaccgtgtatttatttatgacacgacgcttcgcgacggaacccagggggaaggcatc
tccctcagtgtggaagacaaagtaaaaatcgcagcacgtttggatcaacttggcgtagcc
tacattgagggcggatggcccggatccaaccccaaagacatggaatttttccagcgggcg
cagcagatgacatggaagcatgccaagattgccgccttcggctcgacctgccgccctggc
agcgaggcttgtgacgatcctaacctgcgggcgctcatcgagtcgggcgcgccggtcgtc
acgatattcggcaaatcctgggattttcatgtcacagcggccctacggaccaccttggaa
gaaaacctgcgtctggtccgcgattcgatcaccttcttgaaaaatcagggccgggaagtg
attttcgacgctgagcacttctatgacggctacaaaggcaatcccgcctatgccaaagag
gtcgtcatgacggcggaaaaagcaggcgccgactggatcgtcctctgcgacaccaacggc
ggcacacttccccacgatgtcctgtccatcacgcaggagatggtcttcaccctgcgggcg
cctgtgggcgtccacgtccacaacgacggcgacctggcagtggccaactccatcatggga
gtcatggccggcgcccgccaggtgcagggcaccatgaacggctatggggaacgctgcggc
aacgtcaatctttgttctgtcatccccaacctccagttgaagatgaagatggagtgcctg
ccggagggcaagttgcagaccttgactgatgcggctcactttgtcggtgagatcgccaac
atgcccctgcgcaacgacatgccttttgtcggtcattcggctttcgcgcacaagggcggc
atccacgtgtcggccttgatgaaggaccccggcacctatgaacacatccagccggaggcg
gtgggcaaccatcggcgcgtcctcgtatccgaactgtccggcatgagcaacgtcatctac
aaggccaaggaactgggcttggatgtaaaccggcagaacgccgatacgaagcagatcatc
gaacagatcaagaacctcgaacatcaaggctttcaatttgaaggggcggaagcgtctttt
gaggtgctcctgcgccgcgccttcggcgaagatccggtgcccttcgttcttgactcgatc
cgcctgatcatcgagaagcgatctgacgccgatttcacctcggaagccatgatcaagctg
cgcgtcggcgaccaagtcgttcatacggccgccgaaggtaacggccccgtcaacgccgtc
gacaacgcgctgcgcaaggcccttctcagccactaccccttcctggccgagtgccatctc
accgactacaaggtgcgtgtcctcgacgggaaagacgccacagaggcaaaagttcgcgtc
ctcatcgagacgcgggactcccacgacgcctgggggactgttggcgtgtcgaccaacatc
atcgaggcctcttggcaggcgttgatggactccttcctgtatggctacatgcgagaacgg
gcccgggcgtcgatagaatcatcccgacctgcctaa
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