Heliomicrobium modesticaldum: HM1_1592
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Entry
HM1_1592 CDS
T00653
Symbol
murF
Name
(GenBank) udp-n-acetylmuramoylalanyl-d-glutamyl-2,6-diaminopimelate--d-alanyl-d-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hmo
Heliomicrobium modesticaldum
Pathway
hmo00300
Lysine biosynthesis
hmo00550
Peptidoglycan biosynthesis
hmo01100
Metabolic pathways
hmo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hmo00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HM1_1592 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HM1_1592 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HM1_1592 (murF)
Enzymes [BR:
hmo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HM1_1592 (murF)
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Paralog
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GFIT
Motif
Pfam:
Peptidase_M23
Mur_ligase_M
Mur_ligase_C
Biotin_lipoyl
Glu_syn_central
Motif
Other DBs
NCBI-ProteinID:
ABZ84162
UniProt:
B0TDC1
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Position
1607609..1609408
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AA seq
599 aa
AA seq
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MAVNEWNVRAVAAITGGQLLSGRPEDPLRYVCERLVDCGKGDVLIPLVNLTDPAGYAARA
ARKGVGVLVLPDRTASAAANAAVAVIGVGSVRDAYFRLVKAYRHRCKARIVAVTGSAGKT
TTKEMIAAVLAEAGEVQKNWRNYNGPYGIGYTLFRLRPHHTFGVVKIGAYIPNSIDFGAR
LVAPEVGVITCIGLGHAAALGGGEGVRREKEKLLTHLPKKGLLVLNGDDPGCRSVDLSRC
QAPVRWVGVECEREDLSLWAERIQVHRDGTRFLLCGLEREIEVELPGFFGRPAVIDALLA
AAVGDHMGLPPESIASGLTKVEYTPRRFSPIRLPGRRLLIDATYNANPHSMSASLESAAK
LAVEGKGLALLGTMSNLGEEAPEQHRAIGRRAAELGFALIALGEQAETMASGATEAGGRV
IYASKQWEKGHVVALALKELPEEGVLLVKASNSVELEIVAEAIEKEAARRSGLVPPLAKI
EPTCYYGFRRHPLTREWFFHEGIDLSARRGTPIAAVADGTVVKVQKDHPTYGNHLEIDHG
GGMVTGYAHAQKIYVEVGEQVTQGQSIAEVGNTGRTTGPHLHFEVRIDGKTVDPYYYVI
NT seq
1800 nt
NT seq
+upstream
nt +downstream
nt
atggccgtgaacgaatggaatgttcgcgccgtggcggcaataacgggggggcagctcctg
tccgggcgcccggaggatccccttcgctacgtctgtgagcgattggtcgattgcggaaaa
ggcgacgtcttgatccccttggtgaatctcaccgatcctgcgggatatgccgctcgggcg
gcccgcaagggggtaggcgttcttgtgttgccggaccggacagcttctgcggcagccaat
gccgctgtggctgtcatcggtgtaggctccgtgagggacgcctattttcgcctggtcaag
gcctatcggcaccgctgcaaggcgcgcatcgtagcggtgacgggttcggcaggtaaaacc
accactaaggagatgatcgccgccgtattggccgaagcgggagaggtacaaaaaaactgg
cgcaactacaacggtccctacgggatcggctatacgctctttcgccttcgtccgcatcac
accttcggggtcgttaaaatcggcgcctacatccccaacagcatcgatttcggcgcccgg
ctggtggcgccggaagtcggcgtcatcacctgtattggattgggccatgccgcagcgctc
ggaggaggcgagggtgtccgccgggaaaaagagaagttgctgacgcaccttcccaaaaag
ggcctgctggtattaaacggcgatgatcctggttgccggagcgtcgatctttcgcgttgc
caggcgcctgttcgttgggtcggtgtagagtgcgagcgggaggatctttccctctgggcg
gagcgaatccaggtgcaccgcgatggaactcggtttctgctctgcggtttggagcgggag
atcgaggtagaactgcctggattttttggtcgcccggcggtgatcgatgcgctgttggct
gcagccgtcggcgatcatatggggcttccgcccgagtccatcgccagcggattgaccaaa
gtggagtatacaccaaggcggttttccccgatccgcttgccggggaggcgattgctgatc
gatgcgacgtacaacgccaacccgcattccatgtcggcatccctggaaagcgccgccaaa
ctcgcagttgaggggaaaggcctggcgctcctcgggaccatgagcaatcttggcgaagag
gcgccggagcaacaccgcgctatcggcaggcgggcagcagaacttggctttgccctcatc
gccctgggagaacaggcggaaactatggcgtccggggcgactgaggctggtggaagggtg
atctacgcctccaagcaatgggagaaagggcacgtcgttgcccttgccctgaaggagctg
cccgaagaaggggtcctgctggtcaaggcttccaacagcgtggaactcgaaatcgtggct
gaagcgattgagaaggaagccgcccgccgttccggcctggttccgcccttggcaaaaatc
gagccaacctgttattacggttttcgacggcatccgctcacccgtgagtggttctttcac
gaggggatcgacctttctgctcgccgggggaccccgattgcggctgtcgctgatggaacg
gttgtgaaggtgcaaaaggatcatcctacctacggcaatcacctggaaatcgatcacggc
ggaggaatggtgacaggctatgcccacgcccagaagatctacgtcgaggtgggagaacag
gtgacccagggacagtccatcgcagaggttggcaataccggccggacgacgggaccacac
ctgcactttgaggtgcgcatcgatggaaagacggtcgatccctattactatgtgatctga
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