Halothiobacillus neapolitanus: Hneap_0446
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Entry
Hneap_0446 CDS
T01104
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hna
Halothiobacillus neapolitanus
Pathway
hna00300
Lysine biosynthesis
hna00550
Peptidoglycan biosynthesis
hna01100
Metabolic pathways
hna01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hna00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Hneap_0446
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Hneap_0446
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Hneap_0446
Enzymes [BR:
hna01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Hneap_0446
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
MMTV_SAg
PilN
Motif
Other DBs
NCBI-ProteinID:
ACX95303
UniProt:
D0KXY0
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Position
469355..470779
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AA seq
474 aa
AA seq
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MMRASLQQVATWLNQLSVQQPDITIQGVSTDTRTLVPGNLFVALKGERFDGHDHLADARL
AGAAAAIVSHLNPDIDLPQIEVEDTLTALQTLGQCWRGQVDPFVIAITGSAGKTTVKQLL
ASICAQAGPTLATLGNLNNDIGVPLTLLSLSDIDQFAVIEMGANHLGEIARLTALARPDV
GLITMAGTAHVGEFGSVDAIVQGKGELFVGLVPEAQAVINLDSYGADRWWAMGSAQRNGF
TLNNDPRARWTGEYNATTERLTIFENGQLLIESQPLPLPGAHNATNLLAAVAVARTAGFS
KEIILAGLNSFTPPAGRMSLVACSEQLTVINDTYNANPESMCAALDYLVGRPGLHLAVLG
DMGELGDLSAALHEEVIAYARGLAIDGLFTLGAAMDVAMKPNAVSSNVSIEYSAKDHADL
ALALVRALDQLASRSASGTPITILLKGSRFMRMERILNQLLPTDGPSPAESEAH
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgatgcgcgcgtcccttcagcaagttgcaacttggctgaatcaattatctgtgcagcag
cccgatatcaccattcaaggcgtgagcacggatacccgtacattggtgccggggaatctg
tttgttgcgctcaaaggtgagcgattcgacgggcatgatcatttggctgatgcccgcttg
gcaggtgctgcggcggccatcgtctctcatttgaatccagatatcgatctgccccagatt
gaagtcgaagatacattgaccgcgctgcaaacccttgggcaatgctggcgcggccaggtt
gatccctttgtgattgccattaccggcagcgcgggcaaaaccacggtcaagcagctgctg
gcgtccatttgtgcgcaagcggggcccactctggcgacgcttggaaatttgaataacgac
atcggcgtgcccttgacgctgctttcgttgagtgacatcgatcaattcgccgtgatcgaa
atgggtgcgaaccacctcggtgaaattgcccgattaaccgctctggccagaccggatgtg
ggcttgatcaccatggccggcaccgcgcatgtgggtgaattcggatcggtcgatgcgatt
gttcagggcaaaggcgagctcttcgttggtttggtgcccgaggcgcaagcggtaattaat
ctcgattcgtatggtgccgatcgctggtgggcgatgggttcggcgcagcgaaacggtttt
acgctgaacaacgacccgcgcgcacgctggacaggtgaatataacgccactaccgagcgc
ctgacgattttcgagaacgggcagttgctgatcgagtcgcaaccccttccgttgccgggc
gcgcacaacgcgaccaatctgctggccgccgtcgcggtggctcgaacagcagggttcagc
aaagaaattatcctggcgggtttgaacagctttacgccaccggcaggccgcatgagcctc
gtggcttgctccgaacagttgactgtcatcaacgacacctacaacgccaaccccgaatcc
atgtgtgccgctttggattatctcgtcggcaggccgggcctgcatctggccgtattgggc
gatatgggtgagttgggtgatctcagcgccgcgctgcatgaagaagtaattgcttatgcg
cgtggcttggcgatcgatggtttgttcacgcttggtgcggccatggatgttgccatgaag
ccgaacgcagtgtcctcgaacgtttcaattgaatattccgccaaagatcacgctgatctg
gctttggcgttggtgcgtgccttggaccaactggcgtcacgatcagctagtggcacgccg
atcaccattttattgaaaggatctcgctttatgcgcatggaacgaattctgaaccagctc
ctgccaacggatggtccgagtccggcagagtcggaggcgcattga
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