KEGG   Halothermothrix orenii: Hore_10850
Entry
Hore_10850        CDS       T00838                                 
Name
(GenBank) ketol-acid reductoisomerase
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
hor  Halothermothrix orenii
Pathway
hor00290  Valine, leucine and isoleucine biosynthesis
hor00770  Pantothenate and CoA biosynthesis
hor01100  Metabolic pathways
hor01110  Biosynthesis of secondary metabolites
hor01210  2-Oxocarboxylic acid metabolism
hor01230  Biosynthesis of amino acids
Module
hor_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
hor_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:hor00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    Hore_10850
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    Hore_10850
Enzymes [BR:hor01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     Hore_10850
SSDB
Motif
Pfam: KARI_N KARI_C 2-Hacid_dh_C F420_oxidored NAD_binding_2 AdoHcyase_NAD ANKLE2_3rd
Other DBs
NCBI-ProteinID: ACL69839
UniProt: B8CX20
LinkDB
Position
1178749..1179741
AA seq 330 aa
MIHVYYDKDANLGLLEEKMIAVLGYGSQGHAQAQNLKDSGLNVIVGLRKGSSSWKKAESD
GFRVFKTSEAVKRADIIQVLIPDEVQSRVYKEDIEPYLEEGNALVFSHGFNIHFGQIVPP
DNVDIFMVAPKSPGHLVRRMYLEGKGVPGLLAVEQDYSGKAKELGLAYAKGIGCTKAGVI
ETTFKEETETDLFGEQAVLCGGVTSLVKAGFEVLVEAGYQPEIAYFECLNELKLIVDLMF
EGGLTKMRHSISDTAQYGDLMVGPRIVNDNVKDEMRSVLKEIQSGEFAKKWILENKANRP
VFNALTSKDENHLIEKVGKKLRDMMPWINE
NT seq 993 nt   +upstreamnt  +downstreamnt
atgattcatgtctattatgataaagacgccaacctgggattacttgaggaaaagatgatt
gctgtactgggttatgggagccagggtcatgcccaggcccagaacttaaaggatagtggt
ctaaatgttatagttggattaaggaaaggttccagtagctggaaaaaagcagaaagtgat
gggtttagggtatttaagaccagtgaggcagttaaaagggccgatatcattcaggtattg
atacctgatgaagttcagagtagagtctataaagaggatattgaaccatacttagaagaa
ggtaatgccctggtattttcacatggatttaatattcattttggacagatagttcctccc
gataatgttgatattttcatggttgccccaaaaagcccgggacaccttgtcaggagaatg
tatcttgaaggaaaaggcgttccagggttactggcagtagagcaggattattcaggtaag
gctaaagaactgggattggcctatgctaaaggaattggttgtacaaaagctggtgtaatt
gagactacctttaaagaagagaccgaaactgatctttttggggaacaggcagttctctgt
ggtggtgttacttcactggttaaggcaggttttgaggtcctggttgaagcaggttatcag
ccagaaatagcatatttcgaatgtctcaatgaattaaagttaatagttgatcttatgttt
gaaggtgggttaacaaagatgaggcattctataagtgatacggcccagtatggagacctt
atggtggggccgaggattgtaaatgataatgtaaaggatgaaatgagaagcgtattgaag
gaaattcagtcaggggaatttgccaaaaagtggattctggaaaacaaggctaaccggccg
gtatttaatgccttaaccagtaaggatgaaaatcacctgattgaaaaggtgggtaaaaaa
ttaagggatatgatgccctggattaatgaatag

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