Helicobacter pylori J99: jhp_1454
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Entry
jhp_1454 CDS
T00020
Symbol
folC
Name
(GenBank) FOLYLPOLYGLUTAMATE SYNTHASE
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
hpj
Helicobacter pylori J99
Pathway
hpj00790
Folate biosynthesis
hpj01100
Metabolic pathways
hpj01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
hpj00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
jhp_1454 (folC)
Enzymes [BR:
hpj01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
jhp_1454 (folC)
6.3.2.17 tetrahydrofolate synthase
jhp_1454 (folC)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
GAPES3
Motif
Other DBs
NCBI-ProteinID:
AAD07034
UniProt:
Q9ZJ61
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All DBs
Position
1602726..1603895
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AA seq
389 aa
AA seq
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MKNSHGLKAFLETKPKEYHKFDPSRFIQIYKDFKNAFFEIQAKVIHVVGTNGKGSTGRFL
TLLLADQGFKVLHFTSPHVFEFRERFYLNGSVVKESVLENAHQQLQSHAFSNACSYFEYA
TLLAVMLAKDCDYLVLEAGLGGEFDSTNALEKTLSVFTPIDYDHKEFLGDSLESIATTKL
KAMGSLNIIAPQQELVLNVAQKIAKDKHAQLIVVQNEISKGVSDYIERHHLAHFLAMNLE
VALKAFETLLPCNKQEVLKNLKPLDLIGRCELLSPNILIDVGHNPHSAKALKEEIKRIFN
APIVLIYNCYQDKDAFLVLEILKSVVKKVLILELHNERIIQLEKLKGILETLGLEHALFE
ELKENENYLVYGSFLVANAFYERYPKKRD
NT seq
1170 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaatagtcatgggttaaaggcgtttttagaaacaaagcctaaggaataccataag
ttcgaccctagccgtttcattcaaatttataaggattttaaaaacgctttttttgagatt
caagccaaagtcattcatgtggtagggactaatggtaagggcagcacagggcggttttta
acccttttattagccgatcaagggtttaaagtgttgcatttcacctcccctcatgttttt
gaattcagggagcgcttttatttgaatggctctgttgttaaagaaagcgttttagaaaac
gcccaccagcaattgcaatcgcacgctttcagtaacgcttgctcgtattttgaatacgct
accttattagctgtcatgctcgctaaagattgcgattatttggttttagaagcagggctt
gggggggagtttgacagcacgaacgctttggaaaaaaccctaagcgttttcacccccatt
gattacgatcataaggaatttttaggggatagtttagaaagcattgcgactactaaatta
aaagcgatgggctctcttaatatcatcgctccccaacaagaactggttttaaatgtggct
caaaaaatcgctaaagacaaacacgcgcaattgattgtggttcaaaatgaaatttcaaaa
ggagtgagcgattatattgaacgccaccatttagcccattttttagcgatgaatttagaa
gtggctctaaaggcgtttgaaacgctattgccatgcaataaacaagaagttttaaaaaac
ctaaagcccctagatttaatcggccgttgcgagcttttaagccctaacattttaatagat
gtggggcataacccccatagcgctaaagccttaaaagaagaaatcaaacgcatctttaac
gctccaatcgttttgatttataattgctatcaagataaagacgcttttttggtgctagaa
attttaaagtctgtggttaaaaaggttttgattttagaattgcataatgaaagaattatc
caattagaaaaacttaaagggattttagaaactttagggttagaacacgccttgtttgaa
gaactgaaagaaaatgaaaattatttggtgtatggctcatttctggtagccaacgctttt
tatgaacgctatccaaagaagagggattga
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