Halanaerobium praevalens: Hprae_0715
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Entry
Hprae_0715 CDS
T01941
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hpk
Halanaerobium praevalens
Pathway
hpk00300
Lysine biosynthesis
hpk00550
Peptidoglycan biosynthesis
hpk01100
Metabolic pathways
hpk01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hpk00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Hprae_0715
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Hprae_0715
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Hprae_0715
Enzymes [BR:
hpk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Hprae_0715
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ADO76869
UniProt:
E3DQH3
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Position
801729..803126
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AA seq
465 aa
AA seq
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MQTLKLKEIVAFTKAELLQGNLDLKVKEIVIDSRDVKTGFLFIAIIGQNKDGHQYLKEAV
KNGASAVIVDRNSPAIQAAYPNLSVLKVEDTTKALQAIAFNYRHKFDDLKVIGITGSAGK
TTTKDMIFSVLSEKYYCLKTEGNYNNQIGLPLTLLRLDGREDFAILEMGMSGLAEIDLLA
KIAVPEIGIITNIAAAHLEQLGSLENIAQAKKELIDNLTAADTAILNYDNQYTKKIGTNS
KAQTIYFGFEKGADARIENYFFNSKTETLKFEFTYQAKNYKFIFNKAGKHNLYNILPALI
IAFKYKLKPEEIQKGLLKTKFSSLRMEFIQLKNKARIINDCYNANPLSVKAALDVLEQIK
AKRKIAILASMLELGEKSLKKHQQIGLYAAAKKIDLLITIGPKAQAIATKARTKMKSEQV
INLANNKECIDFLLSEIKAEDLILIKGSRANKLEEIVDELKSKEL
NT seq
1398 nt
NT seq
+upstream
nt +downstream
nt
atgcagactttaaaattaaaagaaattgttgcttttacaaaagcagagcttttacaagga
aatctcgacttaaaagtaaaagaaattgtaattgatagtcgtgatgtaaaaacaggtttt
ttatttattgcaattattggtcaaaataaagacggtcatcaatatctaaaagaagcagta
aaaaatggagccagtgcagttattgtcgatagaaattctccagctattcaagctgcttat
cctaatttaagtgttttaaaagtcgaagatacaactaaagcattacaggctattgccttt
aattatagacataaatttgatgatttaaaagtaataggcattactggaagtgcaggtaaa
acaactactaaagacatgattttttcagttctatcagaaaaatattactgtttaaaaaca
gaaggtaattataataatcaaattggtttacctttaacacttttgcgtctagatggaagg
gaagattttgctattttagaaatgggaatgagtggtttagctgagattgatttattagcc
aaaattgcagttcctgaaattggaatcataacaaatatagctgctgctcatttagaacaa
ttaggtagtttagaaaatatagctcaagctaaaaaagaattaatagataatttaactgca
gctgatactgcaatattgaattatgacaatcaatatactaaaaaaattggaactaattct
aaagctcaaacaatttactttggttttgaaaaaggtgcagatgccagaatagagaattat
ttttttaattctaaaactgaaactttaaaatttgaatttacttatcaagctaaaaattat
aaatttatttttaataaggctggtaaacataacctttataatattttgcctgctctaata
attgcttttaaatataagcttaaacctgaagaaattcaaaaaggattattaaagaccaaa
ttttctagtttaagaatggaatttattcagttaaaaaataaagctagaataattaatgat
tgttataatgcgaatccactctcagttaaagctgctcttgatgtattagaacaaataaaa
gctaaaagaaaaatagcaattttagcttctatgcttgaattaggagaaaaaagtctaaaa
aaacatcaacaaattggactttatgctgctgccaagaaaatagatttgttgatcacaatt
ggccccaaagctcaagctatagcaactaaagctcgaactaaaatgaagagtgaacaagtg
attaatttagctaacaataaagagtgtatcgattttttactttctgaaataaaagcggaa
gatttaattttaattaaaggttcaagagctaataaattagaagaaatagtagatgaacta
aaaagtaaggagctttaa
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