Helicobacter pylori B8: HPB8_947
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Entry
HPB8_947 CDS
T01262
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hpl
Helicobacter pylori B8
Pathway
hpl00300
Lysine biosynthesis
hpl00550
Peptidoglycan biosynthesis
hpl01100
Metabolic pathways
hpl01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hpl00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HPB8_947 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HPB8_947 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HPB8_947 (murF)
Enzymes [BR:
hpl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HPB8_947 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
FLILHELTA
Motif
Other DBs
NCBI-ProteinID:
CBI66504
UniProt:
D7FE97
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Position
932782..934263
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AA seq
493 aa
AA seq
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MQSLSWLNLAFRWLFITGLGYYIMTLLQWYHYSVFRILTKHHKMRWHGIYFLLPLGVFIL
SYAFKMPFVFDFFCGVIQMPMLIVWAKRNDKPLVFTPRVKRFFIFLLLFLILHEILNTEL
VPLSGISLALGYLCLFIFVLSASLIFEKALSKQYLQTAKDKIASLKNLKVIAITGSFGKT
STKNFLLQILQATFNAHASPKSVNTLLGLANDINQNLDDRSEIYIAEAGARNKGDIKEIT
HLIEPHLVVVAEVGEQHLEYFKTLENICETKAELLDSKRLEKAFCYSVEKIKPYAPKDSP
LIDVSSLVKNIQSTLKGTSFEMLLDSVWESFETKVLGEFSAYNIASAILIAKHLGLETER
IKRLVLELNPIAHRLQLLEVNQKIIIDDSFNGNLKGMLEGIRLASLHKGRKVIVTPGLVE
SNTESNETLAQKIDGVFDVAIITGELNSKTIASQLKTPQKILLKDKAQLENILQATTIQG
DLILFANDAPNYI
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgcaaagtcttagttggctgaatttagcgtttcgttggctctttataacagggcttggc
tattatataatgactttgttgcaatggtatcattacagcgtgtttaggatcttaaccaag
caccacaaaatgcgttggcatgggatttattttttattgcctttaggggtgtttatccta
tcgtatgctttcaaaatgccgtttgtttttgatttcttttgcggtgttattcaaatgccc
atgctcattgtttgggccaaacgcaacgacaagcccttagttttcacgccaagggtgaag
cgcttttttatcttcttattattatttttaatcttgcatgaaatcttaaatacagaatta
gtccccttgagtgggatttcactcgcgctaggctatttgtgtttgttcatatttgtttta
agcgcttctttaatctttgaaaaagccttatccaagcagtatttgcaaaccgctaaagat
aaaatcgcctctttaaagaatttaaaagtcatcgccattaccggaagctttgggaaaacc
agcaccaaaaatttcttgcttcaaatcttacaagccacattcaacgcgcatgcaagcccc
aaaagcgtcaatacccttttagggcttgcgaatgatattaaccagaatttagacgatagg
agcgaaatctatatcgctgaagccggggcaaggaataagggcgatattaaagaaatcacc
cacctcattgaaccgcaccttgttgtggttgcagaagtgggcgaacagcatttagaatac
tttaaaactttagaaaatatttgcgagactaaagcggaattattggattccaaacgcttg
gaaaaagccttttgttactctgtagaaaaaatcaagccctatgccccaaaagatagccct
ttaatagatgtttctagcctggttaaaaacatccaatccactttaaaaggcacttctttt
gaaatgcttttagatagcgtttgggaaagctttgaaacaaaggttctaggggagtttagc
gcttataatatcgcttcagccattttaatcgccaagcatttaggcttagagaccgaaagg
atcaaacggcttgttttggaactcaaccctattgcccatcgtttgcaacttttggaagtg
aatcaaaaaatcatcatagacgatagctttaatgggaatttaaagggcatgttagaaggc
attcgtttagcgagtttgcacaaagggcgtaaagtcatcgtaacaccgggattagtggaa
agcaatacagaaagtaatgaaactttagcgcaaaaaatagacggggtttttgatgtcgct
atcatcacaggggagttgaattccaaaacgattgcttcacaattaaaaaccccccaaaaa
atcttactcaaggataaggcacaattggaaaatatcttacaagccaccacgattcaaggc
gatttgattttattcgctaatgacgcccctaattacatttag
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