Helicovermis profundi: HLPR_10660
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Entry
HLPR_10660 CDS
T09891
Symbol
cobA
Name
(GenBank) uroporphyrinogen-III C-methyltransferase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
hprf
Helicovermis profundi
Pathway
hprf00860
Porphyrin metabolism
hprf01100
Metabolic pathways
hprf01110
Biosynthesis of secondary metabolites
hprf01120
Microbial metabolism in diverse environments
hprf01240
Biosynthesis of cofactors
Module
hprf_M00924
Cobalamin biosynthesis, anaerobic, uroporphyrinogen III => sirohydrochlorin => cobyrinate a,c-diamide
Brite
KEGG Orthology (KO) [BR:
hprf00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
HLPR_10660 (cobA)
Enzymes [BR:
hprf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
HLPR_10660 (cobA)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
HLPR_10660 (cobA)
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
DUF5088
Motif
Other DBs
NCBI-ProteinID:
BEP28735
UniProt:
A0AAU9EQH9
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Position
1247990..1249498
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AA seq
502 aa
AA seq
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MKNKVYLVGAGPGDINLITVKGKKLIEKADVLIYDRLANKKFLQYKKDDCELYYVGKASS
NHTLTQDEINKLIVNKAKENLLVVRLKGGDPYVFGRGAEEGEFLLKNDLDFEVVPGITSA
IGGLAYAGIPITHRDFASSFHVFTGHFKSDDRDHNWDAIALLKGTLVFLMGLSNVKNICS
NLESYGKSKETPVAIISNATRTNQEIIRGTIENISEVLAKSSIVSPALLVVGDVVNLSKI
LSSPLDGKLRGKKIIVTRSRKQSSSLTSSLESFGANVIEMPAIKIKKILKENEFKIHINE
LSKITHIIFTSVNGVEIYFEELLKNNYDARKLAGIKIVAIGSSTRNKLKQYGIIADIMPK
KFVAEEVFKSIKGTIDSSSYVVLPRAKGSRKYLLDEISSICKTKEILLYESIKDEELIKT
DISEVENTDYITFTSSSTVKNFIESFDTKSVDLINTKKIISIGPITSATLKEYGVNNVIE
ADEYTIDGIIDVLLKDNEVKNV
NT seq
1509 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaataaagtatatttagttggggctggtcctggggatatcaatttaattactgta
aaggggaaaaagcttattgaaaaagctgacgtccttatatatgataggttagcaaataag
aaatttttgcaatacaaaaaagatgactgtgaactttattacgtaggaaaagcaagctca
aatcatacactgacgcaagatgaaattaataaacttatagtcaataaagctaaagaaaat
ctgttagttgtaaggttaaaaggcggagatccatatgtttttggaagaggagcagaggaa
ggtgaatttttacttaaaaatgatcttgactttgaagttgttcctggtataacttctgca
ataggtggacttgcttatgcgggaattccaattacacaccgtgattttgcatcatctttt
cacgtttttacaggccactttaaaagtgatgatagagaccataactgggatgctattgcc
ttgttaaaaggaactttagtttttttaatgggactaagtaatgtgaaaaatatatgctct
aatttagaaagttatggtaaatcaaaagaaacgcctgttgcgattattagtaatgcgact
agaactaaccaagagattataagaggtacaattgaaaatattagtgaagttttagctaaa
tcttccattgtaagtcctgcgcttttagttgttggcgatgtagttaatttatctaaaata
ttaagctctccccttgatggtaagttaagaggaaaaaaaataattgtaacaagaagccga
aaacagagtagttcattaacttcttcccttgaatcatttggagctaatgtcattgaaatg
ccagcaattaaaataaaaaaaatacttaaagaaaatgaatttaaaattcatataaatgaa
ttaagtaaaattactcatataatttttactagtgttaatggagtagaaatatattttgaa
gaactattaaaaaataactatgatgcaagaaaattagcaggaattaaaatcgttgctatt
gggtcatcaactaggaataaacttaagcaatatggaattattgctgatattatgccaaag
aaatttgttgcagaagaagtatttaaatctattaaaggaacaatagattcatcgagttat
gtagttttgccaagagctaaggggtcaagaaaatatttattagatgaaatttctagcatt
tgtaagactaaagagatacttctttatgaatctataaaagatgaagaattaattaaaaca
gatatttcagaagttgaaaataccgattatattacttttacaagttcttcaacggttaaa
aattttattgaatcttttgatacaaagtcagttgatctaattaacactaagaaaataatt
tccattggtccaataacatctgcaactttaaaagagtatggagttaacaatgttattgaa
gcagatgaatacacaattgatggaattatagatgtgttattaaaagataatgaggtgaaa
aatgtttaa
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