Helicobacter pylori Shi470: HPSH_03140
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Entry
HPSH_03140 CDS
T00742
Name
(GenBank) UDP-MurNac-pentapeptide presynthetase (murF)
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hps
Helicobacter pylori Shi470
Pathway
hps00300
Lysine biosynthesis
hps00550
Peptidoglycan biosynthesis
hps01100
Metabolic pathways
hps01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hps00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HPSH_03140
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HPSH_03140
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HPSH_03140
Enzymes [BR:
hps01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HPSH_03140
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
FLILHELTA
Motif
Other DBs
NCBI-ProteinID:
ACD48074
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Position
complement(598645..600057)
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AA seq
470 aa
AA seq
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MTLLQWYHYSVFRILTKHHKMRWHGIYFLLPLGVFILSYAFTMPFVFDFFCGVIQMPMLI
VWAKRNDKPLVFTPRVKRFFIFLLLFLILHEILNTELVPLNGISLALGYLCLFIFVLSAS
LIFEKVLSKRYLQTAKDKIASLKNLKVIAITGSFGKTSIKKFLLQILQTTFNTHASPKSV
NTLLGLANDINQNLDDRSDIYIAEAGARNKGDIKEITHLIEPHLAVVAEVGEQHLEYFKT
LENICETKAELLDSKRLEKAFCYSVEKINPYAPKDSPLIDYSSLVKNIQSTLKGTSFEML
IGSVWESFETKVLGKFNAYNIASAILIAKHLGLETERIKRLVLELNPIAHRLQLLEVNQK
IIIDDSFNGNLKGMLEGIRLASLYEGRKVIVTPGLVESNTESNETLAQKIDEVFDVAIIT
GELNSKTIASQLKTPQKILLKDKAQLENILQATTIQGDLILFANDAPNYI
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
atgactttattgcaatggtatcattacagcgtgtttaggatcttaaccaagcaccacaag
atgcgttggcatgggatttattttttattgcctttgggggtgtttatcctatcgtatgct
ttcacaatgccgtttgtttttgatttcttttgcggcgttattcaaatgcccatgctcatt
gtttgggccaaacgcaacgacaagcctttagttttcacgccaagggtgaagcgctttttt
atcttcttattattatttttaatcttgcatgaaatcttaaatacagaattagtccctttg
aatgggatttcgctcgcgctaggctatttgtgtttattcatattcgttttaagcgcttct
ttaatctttgaaaaagtcttatccaagcggtatttgcaaaccgctaaagataaaatcgcc
tctttaaaaaatttaaaagtcatcgccattacaggaagctttgggaaaaccagcattaaa
aaattcttgcttcaaatcttacaaaccacattcaacacgcatgcaagccccaaaagcgtc
aatacccttttagggcttgcgaatgatattaaccagaatttagacgataggagtgatatc
tatatcgctgaagccggagcaaggaataagggcgatattaaagaaatcacccaccttatt
gaaccgcaccttgccgtggtcgcagaagtgggcgaacagcatttagaatattttaaaact
ttagaaaatatttgtgagactaaagcggaattattggattccaaacgcttagaaaaagcc
ttttgttactctgtagaaaaaatcaatccctatgcccctaaagacagccctttaatagac
tattctagcctggttaaaaacatccaatccactttaaaaggcacttcttttgaaatgctt
ataggtagcgtttgggaaagctttgaaacaaaggttttaggtaaattcaacgcttataat
atcgcttcagccattttaatcgctaagcatttaggcttagaaacagaaaggatcaaacgg
cttgttttagaactcaaccccattgcccatcgtttgcaacttttggaagtgaatcaaaaa
atcattatagacgatagctttaatgggaatttaaagggcatgttagagggcattcgtttg
gcgagtttgtatgaagggcgtaaagtcattgtaacaccgggattagtggaaagcaataca
gaaagtaatgaaactttagcgcaaaaaatagatgaagtttttgatgtcgctatcatcaca
ggggagttgaattccaaaacgattgcttcacaattaaaaaccccccaaaaaatcttactc
aaggataaagcgcaattggaaaatatcttacaagccaccacgattcaaggcgatttgatt
ttattcgccaatgacgcccctaattacatttag
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