Hydrogenophaga pseudoflava: HPF_12010
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Entry
HPF_12010 CDS
T06073
Symbol
purL
Name
(GenBank) Phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
hpse
Hydrogenophaga pseudoflava
Pathway
hpse00230
Purine metabolism
hpse01100
Metabolic pathways
hpse01110
Biosynthesis of secondary metabolites
Module
hpse_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
hpse00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
HPF_12010 (purL)
Enzymes [BR:
hpse01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
HPF_12010 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
QBM28416
UniProt:
A0A4P6X1H1
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All DBs
Position
complement(2484683..2488690)
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AA seq
1335 aa
AA seq
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MTLHLRFFDGGNAISDFKVQQLLPRLQGISDKITGLSARFVHLASFDAEPDAATVERLGQ
LMTYGEPATEAFVAAEKAGAPALYVLPRLGTVSPWASKATDIAHNCGLALHRVERLVEFR
IGLKSGLLGKASLSEDQLRAVADLLHDRMTEAVTTERSQAEALFTELHPAPMEHVDVLGG
GRAALEKANGEWGLALADDEIDYLVNAFNGLKRNPTDVELMMFAQANSEHCRHKIFNAQF
TIDGVAQDKSLFGMIRHTHQTSPQHTIVAYSDNASIMEGHQLERFVAKAGGNASPAYQAE
AAQHHILMKVETHNHPTAISPFPGASTGAGGEIRDEGATGRGSKPKAGLTGFTVSKLWGG
LSDQPGGKPEHIASPLQIMTEGPLGGAAFNNEFGRPNLLGYFREYEQDVGGVTRGYHKPI
MIAGGLGQIDAGQTKKIDFPAGTLLIQLGGPGMKIGMGGGAASSMATGTNAASLDFDSVQ
RGNPEIERRAQEVINHCWAQGDKNPVLFIHDVGAGGLSNAFPELVNDAGRGARFDLRAVP
LEESGLAPKEIWCNESQERYVLAIAPESLEQFKAFCERERCPFSVVGVATEERHLSLVDE
GNESPVDMPMDVLLGKPPKMHRDVKTVQRTFKPMDLTGVSLEKAVIDVLSHPTVASKRFL
VTIGDRTVGGLTHRDQMVGPWQVPVADCAVTLADYAGFAGEAMSMGERTPLASINAAASG
RMAVAEAITNLLAAPIELPRVKLSANWMAACGEPGEDADLYATVKAIGMELCPALDVSVP
VGKDSLSMRTQWTADGEKKKVTSPVSLIVSAFATLADVRGTLTPQLNRDIDDTTLVLVDL
GKGRNRLGGSVLGLTLGQPGDEVPDLDSPQDLINLVNAVNALRAKGQILAYHDRSDGGLL
AAAAEMAFAGHVGVSLNVDMLVTEGDGISDSRMDTGDAKNWAQQVSARREELTLKALFSE
ELGVVLQVKTEDRNAVMQTLREHGLSKHSHFVGKTRPASSSIDVGKGQLQVWRDTKAVFS
ASLYDLQQVWDSVSWKINQQRDNPACADSEHAAAGFPEDPGMHVALTFDPLDNVAAPFLN
LSKPKVAILREQGVNSHVEMAYAFTQAGFEAYDVHMTDLQSGRAKLADFKGVVACGGFSY
GDTLGAGIGWARSITFNPVLSEQFQGFFGRADTFGLGVCNGCQMFAELADIIPGAEAWPR
FTTNQSERFEARLSMVEVLESPSLFLQGMAGSRLPIAVAHGEGFANFKHRGNPAQAIAAM
RFVDNSGAATEQYPFNPNGSPGGLTAVTTADGRFTAMMPHPERVFRNIQMSWTSGSASDL
SPWMRIWRNARKFVG
NT seq
4008 nt
NT seq
+upstream
nt +downstream
nt
gtgaccctgcacctgcgcttttttgacggcggcaacgccatcagcgacttcaaagtccag
caactcctgccccgtctgcagggcatttccgacaagatcaccggcctctcggcccgcttc
gtgcacctggcgtccttcgacgccgagcccgacgccgccacggtggagcgcctgggccag
ctgatgacctacggcgagccggccaccgaggcctttgtcgccgccgaaaaggccggcgcg
cccgcgctctacgtgctgccccgcctgggcaccgtctcaccctgggcctcgaaggccacc
gacatcgcacacaactgcggcctggcgctgcaccgcgtcgagcgcctggtcgaattccgc
atcggcctcaagagcggcctgctgggcaaggccagcctgagcgaagaccagctgcgcgcc
gtggccgacctgctgcacgaccgcatgaccgaggccgtgaccaccgagcgcagccaggcc
gaagcccttttcaccgaactgcaccccgcgcccatggagcatgtggacgtgctgggtggt
ggtcgcgcagcgctggagaaggcaaacggcgaatggggcctggccctggccgacgacgag
atcgattacctggtcaacgccttcaacggtctcaagcgcaacccgaccgacgtcgagctg
atgatgttcgcgcaggccaacagcgaacactgccgccacaagatcttcaacgcgcagttc
accatcgacggtgtggcgcaggacaagagcctgttcggcatgatccgccatacgcaccag
acgagtccgcagcacaccatcgtggcgtactcggacaacgcgtccatcatggaaggccac
cagctggagcgcttcgtcgccaaggccggcggcaatgcgtcgcccgcctaccaggccgaa
gccgcgcagcaccacatcctgatgaaggtggaaacgcacaaccacccgaccgcgatttcc
ccgttccccggcgcctccaccggcgcgggcggcgagatccgcgacgagggcgcgaccggc
cgcggctccaagcccaaggcgggcctcaccggcttcaccgtctccaagctctggggtggt
ttgagcgaccagccgggcggcaagcccgagcacatcgccagcccgttgcagatcatgacc
gagggcccgctgggcggcgccgcgttcaacaacgagttcggtcgtccgaacctgctgggc
tacttccgcgagtacgagcaggacgtgggcggcgtgacccgcggttaccacaagcccatc
atgatcgcgggcggcctgggccagatcgacgccggccagacgaagaagatcgatttcccg
gccggtacgctgctgatccagctcggcggcccgggcatgaagatcggcatgggcggcggt
gccgccagctccatggccaccggcaccaatgccgcctcgctggactttgacagcgtgcag
cgtggcaaccccgagatcgagcgccgggcgcaggaggtcatcaaccactgctgggcgcag
ggtgacaagaacccggtgctgttcatccacgacgtgggcgcgggtggcctgtccaacgcc
ttccccgagctggtgaacgacgccggccgcggcgcgcgctttgatctgcgcgccgtgccg
ctggaagagagcggtctggcgcccaaggaaatctggtgcaacgagagccaggagcgctac
gtgctggccatcgcgcccgagtcgctggaacagttcaaggctttctgcgagcgcgagcgc
tgcccgttctcggtcgttggcgtggcgaccgaagagcgccacctgtcgctggtggacgag
ggcaacgaaagcccggtcgacatgccgatggacgtgttgctaggcaagccgcccaagatg
caccgcgacgtcaagacggtccagcgcacattcaagccgatggacctgaccggcgtgtcg
ctggaaaaggccgtgatcgacgtgctgagccacccgaccgtcgcctccaagcgcttcctg
gtcaccatcggcgaccgcacggtgggtggactgactcaccgcgaccagatggtgggcccc
tggcaggtgccggtggccgactgcgccgtgaccctggccgactacgccggtttcgccggt
gaagccatgtccatgggcgagcgcacgccgctagcttcgatcaacgctgcggcttcgggc
cgcatggcggtggccgaagcgatcaccaacctgctggctgcccccatcgaactgccgcgc
gtcaagctgtcggccaactggatggccgcttgcggcgaacccggcgaagacgccgacctg
tacgccactgtcaaggccatcggtatggagctgtgcccggcgctggacgtgtcggtgccc
gtgggcaaggacagcctgtccatgcgcacgcagtggaccgccgacggcgaaaagaagaag
gtcacctcgccggtgagcctgatcgtcagcgccttcgcgacgctggccgacgtgcgcggc
acgctcacgccgcagctcaaccgcgacatcgacgacaccacgctggtgctggtcgacctg
ggcaagggccgcaaccgcctgggcggcagtgtgctgggcctgacgctgggccagccgggc
gacgaggtgcccgatctggacagcccgcaagacctgatcaacctggtcaacgccgtgaac
gcgctgcgcgccaagggccagatcctggcctaccacgaccgttcagacggcggcctgctg
gccgcggcggccgagatggccttcgccggtcatgtgggcgtgtcgctgaacgtggacatg
ctggtcaccgaaggcgacggcatttccgacagccgcatggacaccggcgatgccaagaac
tgggcgcagcaggtcagcgcccgccgcgaggaactcacgctcaaggccctattcagcgaa
gagctgggcgtcgtgctgcaggtgaagaccgaagaccgcaacgccgtgatgcagaccctt
cgcgagcacggcctgtccaagcacagccacttcgtcggcaagacccgcccggcgtcctcg
tccatcgacgtgggcaagggccagctgcaggtctggcgcgacaccaaggccgtgttcagc
gccagcctgtacgacctgcagcaggtctgggacagcgtcagctggaagatcaaccagcag
cgcgacaacccggcctgcgccgacagcgaacacgccgccgccggttttccggaagacccg
ggcatgcacgtggccctgacgttcgacccgctggacaacgtggctgcgccgttcctgaac
ctgagcaagccgaaggtcgcgatcctgcgcgagcagggcgtgaactcgcacgtggagatg
gcctacgccttcacccaggccggctttgaggcctacgacgtgcacatgaccgacctgcag
tcgggccgcgccaagctggccgacttcaagggcgtggtcgcctgtggcggcttcagctat
ggcgacacgctgggcgccggcatcggctgggcgcgcagcatcaccttcaacccggtgctg
tccgagcagttccagggcttcttcggccgcgccgacaccttcggcctgggcgtgtgcaac
ggctgccagatgttcgccgagctggccgacatcatccccggtgccgaggcctggccgcgc
ttcaccaccaaccagagcgagcgtttcgaagcccgcctgtccatggtggaagtgctggaa
tcgcccagcctgttcctgcagggcatggccggcagccgcctgccgatcgcggtggcgcac
ggcgaaggctttgccaacttcaagcaccgcggcaacccggcgcaggccatcgccgccatg
cgtttcgtcgacaacagcggcgccgccaccgagcagtacccgttcaacccgaacggcagc
ccgggcggcctgacggcggtcaccacggccgacggccgcttcacggccatgatgccgcac
cccgagcgcgtgttccgcaacatccagatgagctggaccagcggcagcgccagcgacctg
agcccgtggatgcgcatctggcgcaacgctcgcaagttcgtcggctga
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