Helicobacter pylori 83: HMPREF0462_0670
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Entry
HMPREF0462_0670 CDS
T01915
Name
(GenBank) Mur ligase middle domain protein
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hpx
Helicobacter pylori 83
Pathway
hpx00300
Lysine biosynthesis
hpx00550
Peptidoglycan biosynthesis
hpx01100
Metabolic pathways
hpx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hpx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HMPREF0462_0670
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HMPREF0462_0670
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HMPREF0462_0670
Enzymes [BR:
hpx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HMPREF0462_0670
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
FLILHELTA
Motif
Other DBs
NCBI-ProteinID:
AEE70275
UniProt:
F4D5K0
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All DBs
Position
complement(646292..647773)
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AA seq
493 aa
AA seq
DB search
MQSISWLNLAFRWLFITGLGYYIMTLLQWYHYSVFRILTKHHKMRWHGIYFLLPLGVFIL
SYAFTMPFVFDFFCGVIQIPMLIVWAKRNDKPLVFTPRVKRFFIFLLLFLILHEILNTEL
VPLNGISLALAYLCLFAFVLSASLIFEKVLSKQYLQTAKDKIASLKNLKVIAITGSFGKT
STKNFLLQILQTTFNVHASPKSVNTLLGLANDINQNLDDKSEIYIAEAGARNKGDIQEIT
RLIEPHLAVVTEVGEQHLEYFKTLENICETKAELLDSKRLEKAFCYSVEKIKPYAPKDSP
LIDYSSLVKNIQSTLKGTSFEMLIGSVWENFETKVLGKFNAYNIASAILIAKHLGLETER
IKRLVLEFNPIAHRLQLLEVNQKIIIDDSFNGNLKGMLEGIRLASLYEGRKIIVTPGLVE
SNTESNETLAQKIDEVFDVAIITGELNSKTIASQLKTPQKILLKDKAQLENILQATTIQG
DLILFANDAPNYI
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgcaaagtattagttggctgaatttagcgtttcgttggctctttataacagggcttggc
tattatataatgactttattgcagtggtatcattacagcgtgtttaggatcttaaccaag
caccacaaaatgcgttggcatgggatttattttttattgcctttgggggtgtttatccta
tcgtatgctttcacaatgccgtttgtttttgatttcttttgcggcgttattcaaataccc
atgctcattgtttgggccaaacgcaacgacaaacctttagttttcacgccaagggtgaag
cgcttttttatcttcttattattatttttaatcttgcatgaaatcttaaatacagaatta
gtccctttgaacgggatttcgctcgcactcgcttatttgtgtttattcgcattcgtttta
agcgcttctttaatctttgaaaaagtcttatccaagcagtatttgcaaaccgctaaagat
aaaatcgcctctttaaaaaatttaaaagtcatcgccattaccggaagctttgggaaaacc
agcaccaaaaatttcttgcttcaaatcttacaaaccacattcaatgtgcatgcaagcccc
aaaagcgtcaatacccttttagggcttgcgaatgatattaaccagaatttagacgataag
agtgaaatttatatcgctgaagccggggcaaggaataagggcgatattcaagaaatcacc
cgccttattgaaccgcaccttgccgtggtcacagaagtgggcgaacagcatttagaatat
tttaaaactttagaaaatatttgcgagactaaagcggaattattggattccaaacgctta
gaaaaagccttttgttactctgtagaaaaaatcaagccctatgcccctaaagacagccct
ttaatagactattctagcctggttaaaaacatccaatccactttaaaaggcacttctttt
gaaatgctgataggtagcgtttgggaaaactttgaaacgaaagttttaggcaaattcaac
gcttataatatcgcttcagccattttaatcgctaaacatttaggcttagaaacagaaagg
atcaaacggcttgttttggaattcaaccctattgcccatcgtttgcaacttttggaagtg
aatcaaaaaatcattatagacgatagctttaatgggaatttaaagggcatgttagagggc
attcgtttagcgagtttgtatgaagggcgtaaaatcattgtaacaccgggattagtggaa
agcaatacagaaagtaatgaaactttagcgcaaaaaatagacgaggtttttgatgtcgct
atcatcacaggggagttgaattccaaaacgattgcttcacaattgaaaaccccccaaaaa
atcttactcaaggataaggcgcaattggaaaatatcttacaagccaccacgattcaaggc
gatttgattttattcgctaatgacgcccctaattacatttag
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