KEGG   Hymenobacter sp. BT18: HER32_10925
Entry
HER32_10925       CDS       T06970                                 
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
  KO
K12524  bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]
Organism
hrs  Hymenobacter sp. BT18
Pathway
hrs00260  Glycine, serine and threonine metabolism
hrs00261  Monobactam biosynthesis
hrs00270  Cysteine and methionine metabolism
hrs00300  Lysine biosynthesis
hrs01100  Metabolic pathways
hrs01110  Biosynthesis of secondary metabolites
hrs01120  Microbial metabolism in diverse environments
hrs01230  Biosynthesis of amino acids
Module
hrs_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
hrs_M00527  Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:hrs00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    HER32_10925 (thrA)
   00270 Cysteine and methionine metabolism
    HER32_10925 (thrA)
   00300 Lysine biosynthesis
    HER32_10925 (thrA)
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    HER32_10925 (thrA)
Enzymes [BR:hrs01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     HER32_10925 (thrA)
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     HER32_10925 (thrA)
SSDB
Motif
Pfam: Homoserine_dh AA_kinase ACT_9 ACT_7 ACT NAD_binding_3 GDH2_N Lipase_GDSL_2 DUF5333
Other DBs
NCBI-ProteinID: QIX61664
LinkDB
Position
complement(2595845..2598289)
AA seq 814 aa
MQVLKFGGSSVANAANIGRVLDLAEAAARQQPAVVVVSALGGVTDALIGAGRRAAAADAT
YRELLQELEQRHLAVVRELLPITGQSAVLSVVKTHCNELESLCDGIFALGELSNRTLDKL
VSYGELLSSKVVAAGLGARGAAHQWLDSRQLIRTDARYGHAAVDFAATNDRIQAAVQQAG
APLYVAPGFISSAPDGSTTTLGRGGSDYTAAIFAGALSATQLEIWTDVSGMMTADPRLVR
AARPIPRISYQEAMELSHFGAKVLYPPTIQPVMRQGIPLWIKNTFAPEDAGTLVEVGPPA
NHAFVRGLSSIGPVALLRLEGSGMVGIPGFSRRLFAALAREQVNVILITQSSSEHSICVA
VSAPEAARAQQAADEEFAPEIQAGRLDPLYREDDLAIVALVGEQMKNHPGISGRMFAALG
QNGVNIRAIAQGSSEKNISTVIRQQDVRKAINVLHESFFEATARQVNVVVTGVGNVGRKL
LEQLNRQQPWLLEKLRLNLRVVGLATSKQFVLDEEGIDLSNWQAALEGGQALNLTTFTEQ
LLALNLRNTVFVDVTASADVAQVYAGLLAKSVAVVACNKVAASSEYQSYAHLKSLAQEFN
THFLFETNVGAGLPIIGTLGDLLRSGDEVQRMQAVLSGTLNFVFNNYDGTRPFAEVVRQA
QDEGYTEPDPRLDLTGVDVARKILILAREAGHPLEMSEVANESFLPASCLEGDVPAFYEQ
LAVHEPHFRGLFDAAAAEGKKLRFVASFADGQARVGLQALPPSHDLYSLQGKDNAVLFYT
NRYVEQPLVIKGAGAGAEVTASGVFADVLRAVQS
NT seq 2445 nt   +upstreamnt  +downstreamnt
atgcaggttttgaaatttgggggctcatcggtagccaatgccgcaaacatcggacgggta
ctggacctggccgaagcggctgcccggcagcagcccgccgtggtggtggtatcggcgctg
ggcggcgtaacggatgccctcattggggccggccgccgcgccgccgccgccgatgccacg
taccgggagctgctgcaggaactggagcagcgccacctggccgtggtgcgcgagctgcta
cccatcacggggcagagcgcggtgctgagcgtggtgaaaactcactgcaacgagctggaa
agcctctgcgacggaatttttgccttgggcgagctgtccaaccgcactctcgacaagctg
gtaagctacggggagctgctttcctcgaaggtggtagcggccgggctgggtgcccgcggg
gccgcccatcagtggctggacagccgccagctgattcgcaccgacgcccgctacggccac
gccgccgtggactttgccgccaccaacgaccgtatccaggccgccgtgcagcaggccggg
gccccgctctacgtagccccgggctttatctcctcggcccccgatggcagcaccaccacg
ctgggccggggcggctccgactatactgccgccatctttgccggcgccctcagcgccacg
cagctggaaatctggaccgacgtgagcggcatgatgacggctgacccacgcttggtgcgc
gctgcccgccccatcccgcgcatctcctaccaggaagccatggaactctcgcactttggc
gccaaagtgctgtacccgcccaccatccagccggtgatgcgccagggtattccgctctgg
atcaagaacacctttgcccccgaagatgccggcacgctggtagaagtggggccgcccgcc
aaccacgcctttgtgcggggattgtcgagcattggcccggtggctttgctgcggctcgaa
ggcagcggcatggtgggcattccgggcttttcgcggcggctgtttgcggccctggctcgg
gagcaggtcaacgtgattctcattacccaaagctcttctgagcactccatctgcgtggcc
gtaagtgccccagaagccgcccgcgcccagcaggccgccgacgaggagtttgcgcccgaa
attcaggccggccgcctcgacccgctgtaccgggaagacgacttagccattgtggccctg
gtgggcgagcaaatgaaaaaccaccccggcatcagtgggcgcatgtttgcggcgctgggc
cagaacggggtcaatatccgcgccattgcccagggctcctcggagaagaatatttccacc
gtcatccggcagcaggatgtgcgcaaagccattaacgtgctgcatgaaagcttcttcgaa
gccacggcccgccaggtgaacgtggtggtgacgggcgtgggcaacgtgggccgcaagctc
ctggaacagttgaatcggcaacaaccctggttgctggaaaagctgcgcctgaacctgcgc
gtggtgggcctggcgaccagcaagcagttcgtgctcgacgaagaaggcatcgacctcagc
aactggcaggccgcgctggaaggtgggcaggcgttaaacctgacgactttcaccgagcag
ttgctggccttgaacctgcgtaataccgtgtttgtggacgtgacggccagcgccgatgtg
gcccaggtatacgccgggctgctggcgaaaagcgtggccgtagtggcctgcaacaaggta
gcggcttcctcggagtaccagagctacgcccatctgaagtccctggcccaggagttcaac
acccacttcctgttcgaaacgaacgtgggcgctggtttgcccattattggtaccctgggc
gacctgctgcgcagcggcgacgaggtacagcgcatgcaggcggtgctgtcgggtacgctc
aacttcgtgttcaacaactacgacggcacgcggcccttcgcggaggtggtgcgccaggcc
caggacgagggctataccgagcccgacccgcgcctcgacctcacgggcgtagacgtggcc
cgcaaaatcctgatcctggcccgcgaggccggccacccgctggagatgagcgaggtagcc
aacgagtctttcctgccggcctcgtgcctggaaggcgacgtaccggcgttctacgagcaa
ctggccgtgcacgagccccacttccggggcctgtttgatgcggcggcagccgaaggcaag
aagctgcgctttgtggccagcttcgccgatgggcaggcccgcgtcggcctgcaggccctg
ccgcccagccacgatttatactccctgcaaggcaaggacaacgccgtactgttttacacc
aaccgctacgtagagcagccacttgtcatcaaaggcgctggggccggggccgaggtaact
gcctcgggcgtgtttgccgacgtactccgcgccgtgcagagttag

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