KEGG   VARIANT: 112609v1
Entry
112609v1                      Variant                              
Name
MRAP2 mutation
Gene
MRAP2  melanocortin 2 receptor accessory protein 2 [KO:K25968]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
mutations
OmimVar: 615410
Network
nt06324  GHRH-GH-IGF signaling
Disease
H02106  Genetic obesity
Reference
  Authors
Asai M, Ramachandrappa S, Joachim M, Shen Y, Zhang R, Nuthalapati N, Ramanathan V, Strochlic DE, Ferket P, Linhart K, Ho C, Novoselova TV, Garg S, Ridderstrale M, Marcus C, Hirschhorn JN, Keogh JM, O'Rahilly S, Chan LF, Clark AJ, Farooqi IS, Majzoub JA
  Title
Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity.
  Journal
Science 341:275-8 (2013)
DOI:10.1126/science.1233000
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