| Entry |
|
| Name |
EGFR mutation in glioblastoma
|
| Type |
Gain of function
|
| Gene |
EGFR epidermal growth factor receptor isoform a precursor [KO: K04361]
|
| Organism |
hsa_var Human gene variants (Homo sapiens)
|
| Variation |
EGFRvIII (deletion of exons 2–7 or amino acids 6-273) |
| Network |
|
| Disease |
|
| Reference |
|
| Authors |
Gan HK, Cvrljevic AN, Johns TG |
| Title |
The epidermal growth factor receptor variant III (EGFRvIII): where wild things are altered. |
| Journal |
|
| Reference |
|
| Authors |
An Z, Aksoy O, Zheng T, Fan QW, Weiss WA |
| Title |
Epidermal growth factor receptor and EGFRvIII in glioblastoma: signaling pathways and targeted therapies. |
| Journal |
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| LinkDB |
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