VARIANT: 4014v1
Help
Entry
4014v1 Variant
Name
LOR mutation
Type
Loss of function
Gene
LORICRIN
loricrin cornified envelope precursor protein [KO:
K10385
]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
mutations
OmimVar:
152445
Network
nt06545
Cornified envelope formation
Disease
H00714
Vohwinkel syndrome
Reference
PMID:
8673107
Authors
Maestrini E, Monaco AP, McGrath JA, Ishida-Yamamoto A, Camisa C, Hovnanian A, Weeks DE, Lathrop M, Uitto J, Christiano AM
Title
A molecular defect in loricrin, the major component of the cornified cell envelope, underlies Vohwinkel's syndrome.
Journal
Nat Genet 13:70-7 (1996)
DOI:
10.1038/ng0596-70
LinkDB
All DBs
DBGET
integrated database retrieval system