KEGG   VARIANT: 4233v2
Entry
4233v2                      Variant                                

Name
MET overexpression
Gene
MET  MET proto-oncogene, receptor tyrosine kinase [KO:K05099]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
overexpression
Network
nt06210  ERK signaling
nt06214  PI3K signaling
nt06263  Hepatocellular carcinoma
  Element
N00248  MET-overexpression to RAS-ERK signaling pathway
N00249  MET-overexpression to PI3K signaling pathway
Reference
  Authors
Granito A, Guidetti E, Gramantieri L
  Title
c-MET receptor tyrosine kinase as a molecular target in advanced hepatocellular carcinoma.
  Journal
J Hepatocell Carcinoma 2:29-38 (2015)
DOI:10.2147/JHC.S77038
Reference
  Authors
Kondo S, Ojima H, Tsuda H, Hashimoto J, Morizane C, Ikeda M, Ueno H, Tamura K, Shimada K, Kanai Y, Okusaka T
  Title
Clinical impact of c-Met expression and its gene amplification in hepatocellular carcinoma.
  Journal
Int J Clin Oncol 18:207-13 (2013)
DOI:10.1007/s10147-011-0361-9
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