KEGG   VARIANT: 4233v2
Entry
4233v2                      Variant                                
Name
MET overexpression
Type
Gain of function
Gene
MET  MET proto-oncogene, receptor tyrosine kinase [KO:K05099]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
overexpression
Network
nt06210  ERK signaling (cancer)
nt06214  PI3K signaling (cancer)
nt06263  Hepatocellular carcinoma
nt06526  MAPK signaling
nt06530  PI3K signaling
Disease
H00048  Hepatocellular carcinoma
Reference
PMID:27508192
  Authors
Granito A, Guidetti E, Gramantieri L
  Title
c-MET receptor tyrosine kinase as a molecular target in advanced hepatocellular carcinoma.
  Journal
J Hepatocell Carcinoma 2:29-38 (2015)
DOI:10.2147/JHC.S77038
Reference
PMID:22218908
  Authors
Kondo S, Ojima H, Tsuda H, Hashimoto J, Morizane C, Ikeda M, Ueno H, Tamura K, Shimada K, Kanai Y, Okusaka T
  Title
Clinical impact of c-Met expression and its gene amplification in hepatocellular carcinoma.
  Journal
Int J Clin Oncol 18:207-13 (2013)
DOI:10.1007/s10147-011-0361-9
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