VARIANT: 5091v1
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Entry
5091v1 Variant
Name
PC deficiency
Type
Loss of function
Gene
PC
pyruvate carboxylase [KO:
K01958
]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
mutations
OmimVar:
608786
Network
nt06031
Citrate cycle and pyruvate metabolism
Disease
H00073
Pyruvate carboxylase deficiency
Reference
PMID:
9585612
Authors
Carbone MA, MacKay N, Ling M, Cole DE, Douglas C, Rigat B, Feigenbaum A, Clarke JT, Haworth JC, Greenberg CR, Seargeant L, Robinson BH
Title
Amerindian pyruvate carboxylase deficiency is associated with two distinct missense mutations.
Journal
Am J Hum Genet 62:1312-9 (1998)
DOI:
10.1086/301884
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