KEGG   VARIANT: 5156v1
Entry
5156v1                      Variant                                

Name
PDGFRA amplification
Gene
PDGFRA  platelet derived growth factor receptor alpha [KO:K04363]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
Network
nt06210  ERK signaling
nt06214  PI3K signaling
nt06220  Calcium signaling
nt06273  Glioma
  Element
N00018  Amplified PDGFR to RAS-ERK signaling pathway
N00029  Amplified PDGFR to PLCG-CAMK signaling pathway
N00040  Amplified PDGFR to PI3K signaling pathway
Reference
PMID:1322795
  Authors
Fleming TP, Saxena A, Clark WC, Robertson JT, Oldfield EH, Aaronson SA, Ali IU
  Title
Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors.
  Journal
Cancer Res 52:4550-3 (1992)
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