KEGG   VARIANT: 5156v1
Entry
5156v1                      Variant                                
Name
PDGFRA amplification
Gene
PDGFRA  platelet derived growth factor receptor alpha [KO:K04363]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
amplification
ClinVar: 57074 394609 58030 58029 58028
dbVar: nsv529304 nsv2773339 nsv530293 nsv530292 nsv530291
Network
nt06210  ERK signaling (cancer)
nt06214  PI3K signaling (cancer)
nt06220  Calcium signaling (cancer)
nt06273  Glioma
nt06526  MAPK signaling
nt06528  Calcium signaling
nt06530  PI3K signaling
Disease
H00014  Non-small cell lung cancer
H00042  Glioma
Reference
PMID:1322795
  Authors
Fleming TP, Saxena A, Clark WC, Robertson JT, Oldfield EH, Aaronson SA, Ali IU
  Title
Amplification and/or overexpression of platelet-derived growth factor receptors and epidermal growth factor receptor in human glial tumors.
  Journal
Cancer Res 52:4550-3 (1992)
LinkDB

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