Luo Y, Alexander M, Gadina M, O'Shea JJ, Meylan F, Schwartz DM

JAK-STAT signaling in human disease: From genetic syndromes to clinical inhibition.

J Allergy Clin Immunol 148:911-925 (2021)
DOI:10.1016/j.jaci.2021.08.004

Asano T, Khourieh J, Zhang P, Rapaport F, Spaan AN, Li J, Lei WT, Pelham SJ, Hum D, Chrabieh M, Han JE, Guerin A, Mackie J, Gupta S, Saikia B, Baghdadi JEI, Fadil I, Bousfiha A, Habib T, Marr N, Ganeshanandan L, Peake J, Droney L, Williams A, Celmeli F, Hatipoglu N, Ozcelik T, Picard C, Abel L, Tangye SG, Boisson-Dupuis S, Zhang Q, Puel A, Beziat V, Casanova JL, Boisson B

Human STAT3 variants underlie autosomal dominant hyper-IgE syndrome by negative dominance.

J Exp Med 218:212397 (2021)
DOI:10.1084/jem.20202592