VARIANT: 712v1
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Entry
712v1 Variant
Name
C1QA mutation
Type
Loss of function
Gene
C1QA
complement C1q A chain [KO:
K03986
]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
mutations
OmimVar:
120550
Network
nt06513
Complement cascade
nt06535
Efferocytosis
Disease
H00102
Classic complement pathway component defects
Reference
PMID:
8840296
Authors
Topaloglu R, Bakkaloglu A, Slingsby JH, Mihatsch MJ, Pascual M, Norsworthy P, Morley BJ, Saatci U, Schifferli JA, Walport MJ
Title
Molecular basis of hereditary C1q deficiency associated with SLE and IgA nephropathy in a Turkish family.
Journal
Kidney Int 50:635-42 (1996)
DOI:
10.1038/ki.1996.359
Reference
PMID:
9225968
Authors
Petry F, Berkel AI, Loos M
Title
Multiple identification of a particular type of hereditary C1q deficiency in the Turkish population: review of the cases and additional genetic and functional analysis.
Journal
Hum Genet 100:51-6 (1997)
DOI:
10.1007/s004390050464
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