VARIANT: 732v1
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Entry
732v1 Variant
Name
C8B mutation
Type
Loss of function
Gene
C8B
complement C8 beta chain [KO:
K03998
]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
mutations
OmimVar:
120960
Network
nt06513
Complement cascade
Disease
H00103
Late complement pathway defects
Reference
PMID:
7594510
Authors
Saucedo L, Ackermann L, Platonov AE, Gewurz A, Rakita RM, Densen P
Title
Delineation of additional genetic bases for C8 beta deficiency. Prevalence of null alleles and predominance of C-->T transition in their genesis.
Journal
J Immunol 155:5022-8 (1995)
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