KEGG   Halanaeroarchaeum sulfurireducens M27-SA2: HLASA_1844
Entry
HLASA_1844        CDS       T04261                                 
Symbol
leuA2
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
hsf  Halanaeroarchaeum sulfurireducens M27-SA2
Pathway
hsf00290  Valine, leucine and isoleucine biosynthesis
hsf00620  Pyruvate metabolism
hsf01100  Metabolic pathways
hsf01110  Biosynthesis of secondary metabolites
hsf01210  2-Oxocarboxylic acid metabolism
hsf01230  Biosynthesis of amino acids
Module
hsf_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:hsf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    HLASA_1844 (leuA2)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    HLASA_1844 (leuA2)
Enzymes [BR:hsf01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     HLASA_1844 (leuA2)
SSDB
Motif
Pfam: HMGL-like HCS_D2 AP_endonuc_2
Other DBs
NCBI-ProteinID: ALG82723
UniProt: A0A0F7PFL8
LinkDB
Position
1774092..1775135
AA seq 347 aa
MGTHVIEAGFPANGEAEFEAVRDIAESTNTAVAGLARVVDSDVEAAIDSGVDMVHVFAST
SDVQIEDSMHATREQVLERSISAVERVAEAGADVMFSPMDATRTDHDYLAEVVEAVDEAG
TDWINIPDTTGVASPSRYAEMVSFVDERADARIDVHTHDDFGMATANAIAGIEAGADQVQ
VSVNGIGERAGNAAYEEVVMAAETLYGADTGIDTTQISELSATIEAKSDVPVPVNKPIVG
DNAFAHESGIHAAGVIENSDTFEPGVMTPEMVGAERSLVLGKHTGTHAVREHLEDAGYDP
SKEEVRDVTRQVKDYAVEKRRVTARDLHRFAADVGVEKASESSEVRT
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggggacccacgtcatcgaggcggggttcccggcgaacggcgaggccgagttcgaagcc
gtccgggacatcgccgagtcgacgaacacggcagtcgccggactggcgcgcgtcgtcgac
tccgacgtcgaggcagccatcgactcgggcgtcgacatggtacacgtcttcgcgagtacc
agcgacgtccagatcgaggactccatgcacgcgacgcgcgagcaggtcctcgaacggtcc
atctcggcggtcgaacgggtggcggaggccggggccgacgtgatgttctccccgatggac
gcgacccggaccgaccacgactacctggcggaggtcgtcgaggcggtcgacgaggcaggc
acggactggatcaacatcccggacacgaccggtgtcgcgagtccgtctcggtacgccgaa
atggtgtcgttcgtcgacgaacgcgccgacgcacgcatcgacgtccacacccacgacgac
ttcggcatggccaccgcgaacgccatcgcgggaatcgaggccggcgcggatcaggtccag
gtgtcggtcaacggtatcggcgaacgggcgggcaacgcggcctacgaggaggtcgtcatg
gccgccgagaccctctacggcgcggacacgggcatcgacaccacccagatctccgagctc
tccgcgaccatcgaggcgaaaagcgacgttccggtcccggtcaacaagcccatcgtcggt
gacaacgccttcgcccacgaaagcggcattcacgccgcaggcgtcatcgagaactccgac
accttcgagccgggcgtcatgacccccgaaatggtcggtgccgagcgcagcctggtcctc
ggcaaacacaccggaacccacgccgtcagggagcatctggaggacgcgggctacgatcca
tcgaaggaagaagtccgagacgtgacccgccaggtcaaggattacgccgtcgagaaacga
cgagtcacggcccgggacctccaccgattcgccgccgatgtcggcgtcgaaaaggcatcg
gagagttccgaggttcgcacctga

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