Histophilus somni 2336: HSM_0160
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Entry
HSM_0160 CDS
T00673
Name
(GenBank) glutamate--cysteine ligase, putative/amino acid ligase, putative
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
hsm
Histophilus somni 2336
Pathway
hsm00270
Cysteine and methionine metabolism
hsm00480
Glutathione metabolism
hsm01100
Metabolic pathways
hsm01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
hsm00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
HSM_0160
09106 Metabolism of other amino acids
00480 Glutathione metabolism
HSM_0160
Enzymes [BR:
hsm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
HSM_0160
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GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATP-grasp_3
Dala_Dala_lig_C
RimK
ATPgrasp_ST
GARS_A
GSH-S_ATP
Motif
Other DBs
NCBI-ProteinID:
ACA31363
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Position
170828..173101
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AA seq
757 aa
AA seq
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MKIQHLIKQHQLGLLFQQGSFGLEKESQRVYQDGSVVTTEHPKCFGNRSYHPYIQTDFAE
SQLELITPPNKNLEDSLRWLSAIHEVVLRSLPEDEFIFPLSMPAGLPSDELIKVAQLDNP
EDVAYREHLVQSYGKNKQMVSGIHYNFQLAPELIQTLFDLQQEQKSAVDFQNNLYLKMAK
NFLRYQWVLLYLLSATPTVESNYFKGSSPLGKGEYVRSLRSSKYGYVNDPEVIVSFDSLE
QYAESLEHWVKSGKLIAEKEFYSNVRLRGAKKARDLIQNGIKYLEFRLFDLNPFEQYGMS
LADARFIHHFVLLMIWLDEMPDQQGVELGRSRLAEVALENPLAQTAYREEGEWLLNQLIS
MLQSIGADQSAVSFVREKLAQFADPGLTLCGRLVQEIEQKGGYQKLGAELAKQYKENAFE
RFYALTAFDNMELSTQALMFDLIQQGISFEILDERDQFLRLQFGEHVEYVKNGNMTSKDS
YISPLIMENKVVTKKVLEKAGFNVPQSQEFTSVKQAIVGYSLFEKRAVVIKPKSTNYGLG
ITIFQQGVNNREDFAKAVEIAFREDKEIMVEDYLVGTEYRFFVLGEETLAVLLRVPANVV
GDGIHTVAELVAQKNAHSLRGDGSRTPLKKIALGDIEQLQLKEQGLTVESIPAKDQIVQL
RANSNISTGGDSIDITDEMHLSYKQLAVGIAKAMGAAVCGVDLIISDLKEPAQPDLSSWG
VIEANFNPMMMMHIFPYAGQSRRLTRNVINMLFPEVK
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatccaacatttaattaagcaacatcaacttggcttattgtttcaacaaggctcc
tttggtttagaaaaagaaagccaacgagtttatcaagacggttcggtagtaacaaccgaa
caccctaaatgttttggtaacagatcttaccatccctacattcaaactgattttgcggaa
agtcagctcgaattgatcacgcctcccaataaaaatttagaagatagtttaagatggtta
tccgctattcatgaagttgttttgcgttctttgcctgaggatgaatttatttttccgttg
agtatgccggcaggattgccttcagatgaattgataaaagtcgctcaattggataaccct
gaagatgtggcatatcgtgaacatttagttcagtcttatggaaaaaataaacaaatggtc
agtggaatccattataactttcagttggctccggaactcattcaaaccttatttgattta
cagcaagagcaaaaaagtgcggtagattttcagaataatttatacttgaaaatggcgaaa
aattttcttcgttatcaatgggttttattgtacttattatcagcaacaccaacggtagag
agtaattattttaaaggtagttcgccattaggaaaaggtgaatatgttcgcagtttacgt
tcaagcaaatatggttatgtgaatgatcctgaggtcattgtttcttttgatagtttagaa
caatatgcagaaagtctggagcattgggttaaaagcggaaaactgatagcagagaaagaa
ttttattccaatgtgcgtttacgaggtgcgaaaaaggcgagagatttaattcaaaatgga
attaaatatttagaatttcgcttgtttgatctcaatcctttcgagcaatacggtatgagc
cttgcggatgcaagatttattcatcattttgtactattgatgatttggcttgatgaaatg
ccagatcaacaaggtgttgaactggggcgtagccgtctagcggaagtagctctagaaaat
ccgttggcacaaactgcctatcgagaagaaggtgagtggttacttaatcagttaatcagt
atgttacaaagtatcggggcagaccaaagtgcggtgagttttgtccgagaaaaattagct
caatttgctgatcccgggttgacgttatgtggtcgtttagtccaagaaattgagcagaaa
ggcggttatcaaaaattaggtgcagagcttgccaaacaatataaagaaaatgcttttgag
cgtttttatgcgttaaccgcttttgataacatggaactttcaactcaagccttaatgttt
gatttaattcagcaaggtatcagttttgagatcttggatgaacgagatcaatttttacgc
ttacaatttggtgaacatgttgaatatgtaaaaaatggtaatatgacttcgaaagatagc
tatatttctcctcttattatggaaaataaagtggttacgaaaaaagtattggaaaaggcg
gggtttaatgttccacagagtcaggagtttacttcagttaaacaagcgatagtcggttat
agcctgtttgaaaaaagagcggtcgttattaaacctaaatctactaactatggcttgggg
attacaatttttcagcaaggtgtgaataatagagaagattttgccaaggcagtggaaatt
gcgttccgtgaagataaagaaattatggtggaggattatttagttggtactgaataccgc
ttctttgtgttgggtgaggaaacattggcagttttattacgtgttccggcaaatgtagta
ggcgatggcattcatactgtggctgaattggtagctcaaaaaaatgctcactcattgcgt
ggtgatggtagtcgtacgccattgaaaaaaattgcattaggcgatattgagcaattgcag
ttgaaagagcaaggtttgactgttgagagtattccagctaaagatcaaattgttcagttg
cgggcaaattctaatattagtacaggcggtgacagcattgatataactgatgaaatgcat
ttgagttataaacaactggcggtggggattgcaaaagctatgggggctgctgtgtgcggt
gtggatctgattatttccgatttgaaagaaccggcacagcctgatttaagttcttggggc
gtaattgaagcgaattttaatccaatgatgatgatgcacatcttcccttatgccggacaa
tctagaagattaacaagaaatgtgattaacatgttgtttccggaagtaaagtaa
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