Hippoglossus stenolepis (Pacific halibut): 118100226
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Entry
118100226 CDS
T08308
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
hsp
Hippoglossus stenolepis (Pacific halibut)
Pathway
hsp04010
MAPK signaling pathway
hsp04012
ErbB signaling pathway
hsp04020
Calcium signaling pathway
hsp04510
Focal adhesion
hsp04518
Integrin signaling
hsp04520
Adherens junction
hsp04530
Tight junction
Brite
KEGG Orthology (KO) [BR:
hsp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118100226 (erbb2)
04012 ErbB signaling pathway
118100226 (erbb2)
04020 Calcium signaling pathway
118100226 (erbb2)
09133 Signaling molecules and interaction
04518 Integrin signaling
118100226 (erbb2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
118100226 (erbb2)
04520 Adherens junction
118100226 (erbb2)
04530 Tight junction
118100226 (erbb2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsp01001
]
118100226 (erbb2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsp04147
]
118100226 (erbb2)
04090 CD molecules [BR:
hsp04090
]
118100226 (erbb2)
Enzymes [BR:
hsp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
118100226 (erbb2)
Protein kinases [BR:
hsp01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
118100226 (erbb2)
Exosome [BR:
hsp04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
118100226 (erbb2)
CD molecules [BR:
hsp04090
]
Proteins
118100226 (erbb2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
ABC1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
118100226
NCBI-ProteinID:
XP_035000974
LinkDB
All DBs
Position
21:15779571..15801431
Genome browser
AA seq
1296 aa
AA seq
DB search
MEAVRSLVFVGAVLLGATGALGREVCLGTDMKLTLPSSLENHYETLRLLYTDCKVVHGNL
EITHLHGKPDLSFLQGIVEVQGYVLVAHVSVDLVPLDNLRIIRGSQKYNSSYTLAVLDNT
LNGQGLRTLRLRSLTEILLGSVYIWGNPQLCFPDPQHIIWRDTLDKQTIHSRQHRLQARA
SECPDCSSECGKSCWGETAQDCQALTRINCASGCQRCKGPLPNDCCHMQCAAGCTGPKDS
DCLACRHLNDSGVCRRNCPAPTIYDPISYHSKPNPNRKFNFGATCIKTCPYNYLAMDVAC
TLNCPKANQEVIITHPNGSETQKCELCEGDCPKACYGLGTDNQGVMDNHGITMVTSSNVE
EFNKCKKIFGSLAFFSQSFARDPETNTSGVTLEQLSSFKQLEEITGYLYIEAWPEEWTDL
SVFENLKVIRGRMLYKGVFSLAIQNLHIQSLGLRSLRSVSGGLVLLNNNSKLCYTNSLPW
GTLLHPTQGPQRILSLNQDATVCEAEGHICHPLCKGGCWGPGPGQCVSCKAFQRGTECVE
QCDIYQGDTREYADGSLCVVCHTECRPLNGSASCHGPGADHCTECENAQDGEFCVDHCPS
GVKEDQQTVWKYSNASGHCLPCSTNCSLSCTVTDDRGCPVDNRVTGPGTTIAAAVGGVVL
FFILLALLVFYLRRHKKLKKKETMRRILQEYELVEPLTPSGASPNQAQMRILKETELKKL
RVLGAGAFGTVYKGVWAPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVASPYVC
RLLGICLTSTVQLVTQLMPYGCLLDYVRENKDHICSQFLLNWCVQIAKGMSYLEEVRLVH
RDLAARNVLVKNPNHVKITDFGLARLLDIDETEYHAEGGKVPIKWMALESILHRRFTHQS
DVWSYGVTVWELMTFGAKPYDMIPAREIPDVLEGGQRLPQPPICTINVYMIMVKCWMIDA
ESRPKFKNLVNDFSVMARDPPRYVVIQNDEQMSMSCPVDSQFFRTLMEEEGNNIRELLDA
EEYLVPQPNLFPRIPGDGVQSNGPSRHQSHRQSRDQGLDIDPSITGGPRSMYSSLTTLGR
SQYPTLPLGANNSNGIWTPQYPTLARSPSAGSQSDSVFLDGGPDDPSLPPASPGRYCKDP
TYPGGSQGELETDGPNGFHHPHQFHHSLPRRNHGINHNQTVPEYVNQEVLDFRPGIPDRA
TTLPRKGSRAERRLPNGLNSGHSVENPGYLVPPSCGSSTSPAFDNPYYLDLVAKANAVAG
AGDGAGGMPRHVNGFVTSTAENPEYLGLADTWSGHT
NT seq
3891 nt
NT seq
+upstream
nt +downstream
nt
atggaggcggtgagaagtttggtgtttgtcggggccgtgctgctcggagcgacgggcgcg
ctgggcagagaagtatgcctgggtacagatatgaagctgaccctgccctcgagcctggaa
aaccactacgagaccctgaggctgctctacactgactgcaaggtcgtccacggcaacctg
gagattacacaccttcatgggaaacccgacctctccttcctgcaggggatcgtggaggtg
cagggttatgtactcgtagcccacgtgtcggtggatctggtgcctctggacaacctgcgg
atcatccgaggcagccagaagtacaactccagctacaccttggccgtgctggataacact
ctgaacggacaggggctccggacactgcggcttcgtagcctcacagagatcctgttgggc
agtgtgtacatctgggggaaccctcagctgtgcttcccagacccccagcacatcatttgg
agggacaccttggacaagcagaccattcacagcaggcagcaccgactgcaggctcgagcc
tctgaatgtccagattgttcctcggaatgtgggaaaagctgctggggagaaactgcgcag
gactgccaagccttgactcgtatcaattgtgcgtctggctgtcagcggtgcaaaggtcct
ctgcccaacgactgctgtcacatgcagtgtgctgctggatgcacaggacccaaagactca
gactgcctggcgtgcaggcacttaaacgacagcggtgtgtgtaggaggaactgtcctgca
cctacgatctacgaccccatctcctatcactccaaacccaacccaaacagaaagttcaac
tttggagccacctgcatcaagacgtgtccttataactacctggctatggatgtggcctgt
actttgaattgtcccaaagccaaccaggaagttatcatcacccatcctaatggaagcgag
acgcagaagtgtgaattgtgtgaaggagactgtcccaaagcgtgttatggcctgggtacg
gacaaccaaggcgtcatggacaaccacggcattaccatggtaacatcgtctaatgtggag
gagttcaacaagtgcaagaagatctttggcagtcttgccttcttctctcagagctttgca
cgggaccctgagaccaacacgtcaggtgtgactctggagcagttgagctccttcaagcaa
ctggaggagataacaggttacttgtacattgaagcttggccagaggagtggactgacctg
agtgtgtttgagaacctgaaggtgatccgaggcaggatgctctacaagggagtgttttca
cttgccatccaaaatctgcacatccagtctcttgggttgcgttcactacgcagcgtcagt
ggaggtttggtgctgttgaacaacaattccaagctgtgctacaccaattcactgccctgg
gggactctcctgcatcccacccagggaccccaacgcatcctcagcctcaaccaggacgcc
actgtctgcgaggcagagggacacatttgtcacccgctgtgcaaagggggctgttggggt
ccgggccccggccagtgtgtgtcctgtaaagctttccaacgtggcactgagtgtgtagag
cagtgtgacatctatcagggggacacacgtgaatacgcagacggatctttgtgcgttgtc
tgtcacacagagtgtcgccctctgaacggctccgcctcctgtcatggaccgggtgcagat
cattgcacagagtgtgaaaacgcgcaggacggtgagttttgtgtggaccactgtcccagc
ggcgtgaaggaggatcagcaaactgtgtggaagtacagcaatgcgtccggacactgtctt
ccctgcagcaccaactgctcgctgtcctgcacggtgacggacgacagaggctgccccgtc
gacaacagggtgacaggacccggtacgaccatcgcggctgcagtgggtggggtggtgctc
ttcttcatcttgctggctctgctggttttctacctgaggaggcacaagaagctgaagaag
aaggagaccatgaggaggatcctgcaagaatatgagctggtagagcctctgacacccagt
ggtgcgtcacccaatcaggctcagatgcgtatcctaaaggagacggagttgaagaaactc
agggtgctgggtgcaggggcctttggtaccgtttacaagggagtgtgggctcctgacggg
gagaacgtgaaaataccagtggctattaaggtattacgagagaacacctcgccaaaagcc
aataaagagatccttgatgaagcttatgtgatggcgggggtggccagcccttatgtgtgc
cgtcttctgggaatctgtttgacctccaccgtgcagctggtcactcagctgatgccatat
ggctgcctgctcgactacgtcagggagaacaaggaccacatctgctcccagttcctcctc
aactggtgtgtgcagatcgccaagggcatgagttacctggaggaggtccggctggtccac
agagatctggccgcccgcaacgttctcgtgaaaaacccaaaccacgtgaagatcacagac
ttcggcctcgcccgcctgctcgacatagacgagaccgagtatcacgccgagggagggaag
gtgccaattaaatggatggctctggagtctattctgcacaggaggttcactcatcagagc
gacgtctggagctacggagtgaccgtttgggagctgatgacgtttggagccaaaccgtac
gacatgatcccagcgagggaaatcccagatgtgttggagggaggacaacgacttccccag
ccgcccatctgcaccatcaacgtctacatgatcatggtcaaatgttggatgatcgatgcg
gagagcagaccgaagttcaaaaatctggtgaatgatttcagcgtcatggccagagaccct
cctcgttatgtcgtcattcagaacgatgagcagatgagcatgtcctgccctgtggacagc
cagttcttccggacgctcatggaggaggaagggaacaacataagggagctgctggatgct
gaggagtatctggtgcctcagccgaacctcttccccaggatcccaggagacggggttcag
tccaacgggccgtccagacaccagtcacacaggcagagcagagatcagggattagacatt
gatccgtccatcacaggcggccctcggagcatgtactcctccctgaccactctcggccgc
agccagtaccccaccctaccattaggggccaacaactccaacggcatttggactcctcag
tacccgacgctggctcgcagcccctcggccggtagccagtctgactctgtcttccttgac
ggggggcctgacgacccctcgctgcccccggccagccctggacgctactgcaaagacccc
acgtaccccggcggcagccaaggcgagctggagacagatgggccgaacggctttcatcat
cctcatcagtttcatcactcgctgcccagacgtaatcatggaatcaatcataatcaaact
gtgccagagtacgtcaaccaggaggttctggatttcagaccgggaatcccagatcgtgcc
accacgctgcctcgtaaaggctccagagcagagcgacgcctccccaacggcctgaactcc
ggtcacagcgtggaaaacccaggatacttggtccctccaagctgcgggtcctcaacctct
ccggcctttgacaacccgtactatctggaccttgtggccaaagccaacgctgtagcaggg
gcaggggatggggcaggaggaatgcccaggcatgtgaatgggtttgtgacctccacagca
gagaatccagagtatctgggactagcagacacctggagcggacatacttga
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