Hippoglossus stenolepis (Pacific halibut): 118106095
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Entry
118106095 CDS
T08308
Symbol
arhgef12a
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
KO
K07532
Rho guanine nucleotide exchange factor 12
Organism
hsp
Hippoglossus stenolepis (Pacific halibut)
Pathway
hsp04270
Vascular smooth muscle contraction
hsp04625
C-type lectin receptor signaling pathway
hsp04810
Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:
hsp00001
]
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
118106095 (arhgef12a)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
118106095 (arhgef12a)
09153 Circulatory system
04270 Vascular smooth muscle contraction
118106095 (arhgef12a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsp04131
]
118106095 (arhgef12a)
Membrane trafficking [BR:
hsp04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
118106095 (arhgef12a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RGS-like
RhoGEF
PH_16
PDZ
PDZ_6
PDZ_2
SOS1_NGEF_PH
Pept_S41_N_bact
Motif
Other DBs
NCBI-GeneID:
118106095
NCBI-ProteinID:
XP_035010236
LinkDB
All DBs
Position
4:12473325..12511365
Genome browser
AA seq
1443 aa
AA seq
DB search
MSDTQSSFTDRFPKKANRTSSILSKDHPPDKKPRSDKTSLPSNEFDPTEALVVQKSGSSS
VLAEGKPESCGLVQRCVIIQKDENGFGLTVSGDNPVFVQLVKEDGAAMRAGVQTGDRIIK
VNGTLVTHSNHIEVVKLIKSGSYVALTVLGRPPGLAQIPLSEAESEMLGVSISSPNSPAS
ERPYSPLDRLSSTHPPWDENSSVCNPRVDILQRMLSKEQHELQAMKEEYSKNPSPKLLKD
IQEAKKHIPQLQGQLFKATGATQEAVPGGDADDGSMFESEHTLTSKGDNNTDMSWSSTPL
SHRFGPGSPDSLFPRQTSCSSPKSTPRNSFNSCHSPDAADTTDLDSLSPTTVSSPSSSRL
VSQIIGAEDDYFDSDQEQTNGQCHNFNSIEQLKSRPAHLTAFLHHVISQFDPAPLLCYLY
ADLYKQTNSKETRRVFMDLHTFFIDRGANLKVAVPESISSDLDRRRTELIPEEINRQHVQ
TLQDSLLPDIQKNLEDFRQKRSMGLTVAAAELARLDQERVRDRVTLERERSYAESIITKI
EDILLTTQTTEEEKCTTMQYVIYTYMKHLGVRVKEPRSLESKRVRINFLPKIKKSIKTEK
EGGEEKVKKPRFPSILGPQRRPSRIEAASVGKALDGRPRPQKQLSQPSLGASEHTETGRL
RSSQSSEGSELTHSMSVNTSSPNSTTYSSDTSRDADMGGTPTSGPHRLSDGLQTDSLDGL
PYPASHFDLYSLDQLQEDDRESDRAHEGTPKAIRRLEGLGAADVQSEDDQGTDSEHDPPN
WQQLVGREVLAGLRPHEIKRQEVINELFYTERAHVRMLRVLDHVFYQKLSKESILPPADI
KNIFTNLEEILQLHASILEQMAAVRKRNESSVIDQIGDDLLSWFSGGEEKIKQAVGTFCS
NQPFALEIIKTKQKKDSRFTSFIQEAESNRLCRRLQLKDIIPVEMQRLTKYPLLLENISK
YTDNTVEKDKVKQAADCCRKILNHVNQAVKQSEDKQRLEDYQRRLDLSSLKQTDNPVILE
LKNLDLTKRTMVHEGPLSWKVNKDKTIELYTLLLEDILVLLQKQDERLILKCHSKNLAGT
ADTKHIFSPIIKLNTVLVRSVATDNKSFFVLSMSDNGAQIYELMAPTVADQITWQRLIIQ
RADAMKVKPHTIIPLPQSDGERDDVETITAGVSRLSRDADRTSTGSTQSTDKESSPAPRS
ALPSSLPGNNPFERVKAEEEEQEEEGFVDPELPYQAAEDGREGDSFNVYPSRADEALKTL
AALKQVLVTQLMSQEAAEQSKRSTGARLLRTTSLRTPIDSRARVMVHNGSEKNSSHTEDP
AQDLGSGDTGFFDSPDDYAGYLVLEGYGGPGESSTDDDILASTTGKQLSTSQGCATDSGI
NLRFSSASQAGSLSSFSRQVLSHLRNLQSNLSYLKDVEAKYNNLIRQRPERSSADMDRNK
DKR
NT seq
4332 nt
NT seq
+upstream
nt +downstream
nt
atgagtgacacacagtccagcttcactgacaggtttcccaagaaagcaaacagaaccagc
agcattctcagtaaagaccatcccccagacaagaaacccagaagtgacaaaacctcactt
ccctccaatgagtttgaccctacagaagctctggtggtgcagaagagtggcagcagcagt
gtgctagcagaggggaagcctgagtcctgtggtctggtccagcgatgtgtaatcatccag
aaagatgaaaatggctttgggctcactgtcagtggtgacaacccagtgtttgtgcagctt
gtcaaagaagatggggctgcaatgcgggcaggtgttcagacaggagacaggatcatcaag
gtcaatgggacccttgtaacacattctaaccacattgaagtggtgaagctaatcaaatcg
ggctcctatgtggccctcacagtgttggggcgccctccagggctcgcccagatccctttg
tcggaagcagagtctgaaatgttgggtgttagcatttcctctccaaactccccagcatca
gaacgcccctacagtcctctggaccgcctctcttctacacatccaccatgggatgagaac
agcagtgtctgcaacccaagggttgatatcttgcaaaggatgctctcgaaagagcagcac
gagctgcaggccatgaaggaggagtacagcaagaacccctcccccaaactactgaaagac
atccaggaagctaaaaaacacattcctcagctgcagggtcagctcttcaaggccactggg
gcaacacaggaggcggttccaggtggtgatgcagatgatggtagcatgtttgagtcagag
cacactctcacctcaaagggagacaacaacacagacatgtcctggagcagcacgccttta
tctcacagatttgggcctggatctccagacagtttatttccaagacagacatcctgctcc
agcccaaagagcacacccaggaacagcttcaactcctgccactccccagacgcagcggac
accactgacctggactctctgtcccccaccacagtcagcagtccctcctcttctcgcctc
gtctcacaaatcattggagctgaggacgactactttgattcggaccaggaacagacaaac
ggccagtgtcacaactttaacagcatcgagcagctcaagtctcgccccgcccacctcacg
gccttccttcaccatgtcatctctcagttcgaccctgctcctttgctgtgctacctctat
gctgacctctacaagcagaccaactccaaagagaccagacgggtgttcatggacctccac
accttcttcatcgaccgaggagctaatttgaaagttgctgtccctgaatccatctcttct
gatcttgatcgacggcggacagaactgatcccagaggaaataaacaggcaacacgttcaa
acactgcaggactctctgctccctgacattcagaagaaccttgaggatttcaggcagaag
cgcagtatgggtctaacagtggctgcagctgaattggccagactggaccaagagcgagtc
agagacagggtcactctggagagagagcgatcatatgctgaaagcatcatcaccaagata
gaggatatcctcttaactactcagaccacagaggaagagaaatgcactaccatgcagtat
gtcatctatacatacatgaagcaccttggtgtgagggtgaaggaacctcgcagtctggag
tccaaacgggtccggatcaactttctccccaagatcaagaaaagcataaagacagaaaag
gaaggaggagaagaaaaggtgaagaaacccagatttcccagcatccttggtcctcagcgt
cggcccagccgcatcgaagcagcatctgtgggtaaagccttggatggtcgcccacgacct
cagaagcaattgtctcagccttcactgggggcaagcgagcacacggaaactggtcgttta
agaagcagccaatcaagtgagggctctgagctcacacactccatgtctgtcaacacctca
tcccccaacagcaccacctacagctcagacacgagccgagatgctgatatgggtggaact
ccgacctcaggccctcacaggctgagtgacggccttcagactgactctctggacgggctg
ccataccctgcttcgcactttgacctctacagcctggaccaactgcaagaggacgacaga
gagagtgacagagctcacgagggaacaccaaaggccataagaaggcttgagggactgggt
gcagccgacgtccagagtgaagacgaccagggaacagactctgagcacgaccccccaaac
tggcagcagctggtgggacgagaagtcctagcgggtctccggcctcatgaaatcaagagg
caggaagttatcaatgagctgttttacacggagcgtgcacatgtgcggatgctgagagtt
ttggaccacgttttctaccagaagctttccaaagagagcatcctgcctcccgctgacatc
aagaacatcttcaccaacctggaggagattctgcagctgcatgcttcaatactggagcaa
atggcagccgtgcggaagagaaatgagtcctcagtaattgatcagataggagacgacttg
ctctcctggttcagtggcggagaggagaagatcaagcaggcggtggggacgttctgcagc
aaccagcctttcgctctggagatcattaagaccaagcagaagaaagactcgaggttcact
tcgttcatccaggaggcagagagtaacagactgtgtcgcagactgcagcttaaagacatc
attcctgtggagatgcagcgactcaccaagtaccctctgctactagagaacatctccaag
tacacagacaacacggtggagaaggacaaagtgaagcaggcggcggactgctgcaggaag
atcctaaatcacgtcaaccaggctgtgaagcaatctgaggacaagcagaggctggaggac
tatcagagacgactggacctgtcctctctgaagcagacggataaccccgtgatcctggag
ctaaagaacctggatcttaccaagagaacaatggtgcacgagggacctctgtcatggaaa
gtgaacaaggacaagactattgagttgtacacgctcctcctggaggacatcctggtcctg
ctacagaaacaagatgagcgtctgatcctgaagtgtcacagcaaaaacctggcaggcacc
gcagataccaaacatatcttcagccccatcatcaaactcaacactgtgctggtgcgctct
gtggccacagacaacaagtcctttttcgtcctgtccatgtcagacaacggagcccagatc
tacgagctgatggcgcccacggtcgcagatcagataacgtggcagcgtctaatcattcag
agagcggacgccatgaaagtcaaacctcacaccatcatcccgttacctcagagcgatggg
gagagagacgacgtggagaccatcaccgcaggtgtttccaggctgagtcgagacgcagac
cgcacatccactggcagcacccagtcaacagataaagagagcagtccggcccctagaagc
gcattgccgagctctctacctggaaataatccattcgagagggtgaaggctgaggaggag
gagcaggaggaggaagggtttgtggatccggagcttccttaccaagcggctgaggacggc
agagaaggagactcgtttaacgtttatccctccagagcagacgaagcactgaaaacactg
gcagcattaaagcaggtgttggtgacccagctgatgtcccaggaggctgcagagcaaagc
aaacgctccacaggggctcgtctcctcaggaccacgtctctgcggacacccatcgacagc
cgcgcacgagtgatggtccacaacggctccgagaagaacagctctcacacggaggacccg
gcccaggacctgggctctggggacacgggcttcttcgactctcctgacgattatgcagga
tacttggtcctggagggctacggtggcccgggggagagcagcacagatgacgacatcttg
gcatcaaccacagggaagcagctgagcacctcacaaggctgcgccacggactccggcatc
aacttgaggttctcctcggcgtctcaggccggcagcctctcctctttcagcagacaagtc
ctgtctcacctcagaaaccttcagtccaacctgagctatctgaaggacgttgaggccaag
tacaataatctaatacgccaaaggcctgaaaggtcctcagcagacatggacagaaacaaa
gataagagatag
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