Hippoglossus stenolepis (Pacific halibut): 118118306
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Entry
118118306 CDS
T08308
Symbol
tsc2
Name
(RefSeq) tuberin isoform X1
KO
K07207
tuberous sclerosis 2
Organism
hsp
Hippoglossus stenolepis (Pacific halibut)
Pathway
hsp04115
p53 signaling pathway
hsp04140
Autophagy - animal
hsp04150
mTOR signaling pathway
hsp04218
Cellular senescence
hsp04910
Insulin signaling pathway
hsp05168
Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:
hsp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04150 mTOR signaling pathway
118118306 (tsc2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
118118306 (tsc2)
09143 Cell growth and death
04115 p53 signaling pathway
118118306 (tsc2)
04218 Cellular senescence
118118306 (tsc2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
118118306 (tsc2)
09160 Human Diseases
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
118118306 (tsc2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
hsp01009
]
118118306 (tsc2)
Protein phosphatases and associated proteins [BR:
hsp01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
118118306 (tsc2)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Tuberin
DUF3384
Rap_GAP
Motif
Other DBs
NCBI-GeneID:
118118306
NCBI-ProteinID:
XP_035027265
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All DBs
Position
2:9529054..9556753
Genome browser
AA seq
1902 aa
AA seq
DB search
MNKQASKESLKDKVKGIFGLGTTRPPSKQSDSKPSEFIITTDIIKELQPDCGLSNRIRMM
NHVCELAKSKKFEEHAVEALWKAVEDMLTPEQPPEARHAVLQLLRAIIQGQGERLGPLRA
YFFRVIRDYQPCNEDLSDRLEVFKALTENGKDITYLEEDIARFVLLWMDIGLTSDFLHVL
VNLVKFNSCYLDQNVSTMVQKICLQCNRTTSSTDIEVALQVLDAVVCYNCLPSDSLTVFI
ITLCRTVNVKEFCESCWKLMRKVLGTHLGHSAIYTMCRIMEERIYMEDAPLLRGAVFFVG
MALWGAHRLPALKNTPTLVLPSFYKAMSCANEVVSYEIVLSITRLIKKYGKDLQVVTWDI
LLGIIERLLQQIQTIGSAELKSIVYELLTTVEELYEQNGYHGSTEKFFILVEKCADKRPD
SSVLTLISYRAQSIQPAKDGWIQSLHRLMEKFFRNETRSVIRIKVLHILSFVLSTNRQLY
EDELIEMVVIPQLSGIAEDRDLAVRKQATQLLVDLAEGCNTHHFTSLLDIIERVASRSLI
CSGPLEVSERDPTAESPMEDIKTAILGLLEILQSKLYSLPASHASRVYELLISHLQLHYK
NKYCSAIASSIRLQVFDFFLMMRADSLHRLGVPNKDGAMRFSPYCYCDTGEPEKRVSEKK
PTGSTSPPAGSPAPPAAPPPSTASIRSAYLPYAPAFSVLLQGLKMETDWKVLKLVLDKLP
WMLQYKVLLLTSLCSLDQLCSTLCCMVTDRLISERLKKTPEGFSRTDVQLAVVPVLTAIT
SYHNYLEQSRQRELVQCLETGLIYRCAKQCVVALTMCTVEMPDIMIKLLPALIVKLTHIS
ATVAMASPMLEFLSTLVRLPHLYANFVAEQYVSVFAISLPYTNPSKFNQYIVSLAHHVIA
MWFIRCRLPFRKDFVQYITKGLRSNALLPFDDGHEQSPFRARSTSLNERPKSLRAAKVAK
AAAAVANSSSSPVKELRDLSAMDAFRSRSISVSEHAVRRMHTSTTTCSLGSADENAVTQA
DEGLKTVHLELTETCLDMMARYVFSNFSALPKRSPIAEFLLAGGRSMTWLVGNKLVTITT
SGGVRTQALLGLDMAERLGGGGEMTRSDPSLHTRITKEAPAKLESQSSQQHNRATRIRVR
SISGGHALRAGPAQSLSPLVSPSEGELAAPLSPSTGPTLDGLGPPSSISVAPSTPPPLKD
NPSLADFVPILTQGWAEIFIRRPSGNTSWLMCLENPPSPFSSELGNMPLQELSTVLMAME
GVKEPPAQTTSAPASTAAPAPAPVSEPLTQTHSGVAGKANLIQRSNTVGGFLWSVGLGSA
PSGPPAPGRLHRSISWAESVVVLEEGSGVAAAHSPSDWLESEEFEPMSSDPIFMSADKFT
KTPPPGTLSRSSSTSSQDDEKSTLEEVSEGAIPIDQPTMGPSTPGSQGPELPFQSHSPSQ
GHGLNKSSSSPELQTLPEAFTKAALESETVLVDTLLPRAPSDGKPQQQQPHFEKDKVEVS
AGGDVNGLGGQSHGAEGPAVASSQIGGARMRLEFPTAVAQPGPISPGGGHRPRGHTISVS
APSSRRERRTDRDLYHSRPGPSNTEKISGLSPSFVFLQLYHSPFFGNEANKPLLLPKTQV
IDRAVKVLDQMPPYDTHKIGVVFVGAGQVNNEVSILSNEYGSNRYAAFLTGLGKLIHLKD
CDPDQIFLGGLDQYGDDGEFTYCWHDDIMQAIFHIATLMPNRESDKGCCNKKRHIGNDFV
MVVYNDSGEDYKLGTIKGQFNFVEVIIKPLDFECNLVTLQCRKDLEGLVDTTVAKIVSDR
NLPLLVRQMALHANMASLVHQYRANPSDAYASKWLARLRHIKRIRTRAQEDIQSRSTPGI
SLTQGHTQQNKSFQQSNQAPNPETSGQRKRLVSTVDDFTDFV
NT seq
5709 nt
NT seq
+upstream
nt +downstream
nt
atgaataaacaagcaagcaaggagagtctgaaggacaaggtgaaggggatctttggtctg
gggacaacgcgcccacccagcaaacagagtgatagcaaaccatcggaatttattattacc
acagacatcatcaaggagctccagcccgactgcggcctgagcaatcgcattcgcatgatg
aaccacgtctgcgaactggcaaaatcgaagaaatttgaggagcatgcagtcgaggcacta
tggaaggctgtggaggacatgctcactccagagcagccacctgaggccagacatgctgtc
ctgcagctgctgagggccattatacagggacagggcgagcgacttggccctctgagagcc
tactttttcagggtgatcagagattaccaaccctgcaacgaagacctctctgacaggctg
gaagttttcaaggccttaacagaaaatggaaaagacatcacctacctggaggaggatata
gctcggtttgtcctcctgtggatggacattggcctcacctcagactttctgcacgttctt
gtaaatctggtgaagttcaacagctgctacctggaccaaaatgtctccaccatggtccag
aaaatctgtctccaatgcaacagaacaacatcgtcaacagatattgaggtagctctacag
gtcctggatgcggtggtgtgttacaattgcctgccttcagactctctcaccgtcttcatc
atcacactctgtcgtacagtcaatgtcaaggagttttgtgaatcctgctggaagctgatg
aggaaggtgttgggtactcacctcggccatagcgctatttacaccatgtgccgcatcatg
gaggagaggatatacatggaggatgcaccactgttgagaggagctgtgtttttcgttgga
atggcactgtggggtgcacacagactgcctgctctgaaaaacacacccacattggttctg
ccatctttctacaaggccatgtcgtgtgccaatgaggtggtgtcctatgaaatcgtcctt
tccatcacccggctgatcaaaaagtacggcaaggatctgcaggtggtcacctgggacatc
ctgctgggcatcatagagcgactgctgcagcagatccagacaataggcagtgccgagttg
aagtccatcgtctatgagctgttgacaacagtagaggagctgtacgagcagaacggttat
catggctccacagagaagttcttcattctggtggagaaatgtgctgacaaaagacctgat
tcatcagtgctgacccttatctcgtacagggcccagtctatccagccagccaaggacggc
tggattcagagccttcaccgcctcatggagaaattcttcaggaatgagactcgcagtgtg
ataaggatcaaagtgcttcacatcctgtccttcgttctcagcaccaaccgacagctctac
gaggatgagctgatagaaatggtggtgatcccccagctcagtgggatagctgaagaccgg
gacctggccgtcagaaagcaggccacccagctgctggtggacctggctgagggctgcaat
acgcaccacttcaccagtctattggacatcattgaacgggttgctagtcgctcactgatt
tgttcagggcccctggaggtttctgagagagaccccacggcagagtctcctatggaggac
atcaagactgctatactgggcttgctggaaatcctgcagagcaagctttacagtctacca
gccagccatgccagtcgtgtttatgagttgcttatcagccacctgcagcttcactataaa
aacaaatactgttcagctattgcttccagcattagattacaggtctttgacttcttcctg
atgatgcgagcagactctcttcatcgtctcggagtccccaacaaagacggagccatgagg
ttcagcccttactgctactgtgacacaggggagccagagaagcgagtcagtgaaaagaag
ccgacaggttcaacatctcctcctgctggtagcccagctcccccagccgctcctccccct
tcaacagcctccatacgctcagcctacctgccctatgcacctgcctttagtgtcctcctg
cagggcctcaagatggagaccgattggaaggtgctgaagcttgttctcgacaagctgcct
tggatgctgcagtacaaagtgctgctgctgacgtcactgtgcagcttggaccagctctgt
tcgacactctgctgcatggtgacagatcgtctgatctcagagcgcttgaagaagacccca
gaggggttttcccgcactgatgttcagctggcggtggttcctgtcctcacggcgatcacc
tcctatcacaactacctggagcagtcgagacagagagagctggttcagtgcctcgagact
ggcctcatttaccgctgtgccaagcaatgtgtagtggccctgacgatgtgcacggtggag
atgcctgacatcatgatcaagctccttcccgctcttattgtcaagctcacccacatctct
gccactgttgccatggcgtctcctatgcttgagttcctctccactctggtgcgcctgccc
catctctatgccaactttgtagctgagcagtatgtcagtgtgtttgcaatctctctaccg
tacactaatccctccaagttcaaccagtacattgtgtcactggcccaccatgtgattgct
atgtggttcatacgctgcagacttcccttccgcaaagactttgttcagtacatcacaaag
ggtttgcgttccaacgccctgctgccattcgatgacggacatgagcagagtccatttcgc
gcccgaagcaccagcctcaatgaaagacccaagagtctgcgggcggcaaaagtggcgaag
gcagcagcggcggtagccaatagcagcagctctcctgttaaagagctgagggacctgtca
gccatggacgcgttccgctcccgcagcatcagtgtctccgaacatgcggtccgcaggatg
cacacctcgaccaccacgtgcagcctgggctccgctgatgaaaatgcggtgactcaggca
gacgaggggctgaagaccgtccacctggagctcacggagacctgcctggacatgatggca
cgatatgtgttttccaacttctccgcattgcccaagaggtcacccatagcagagttcttg
ttggcagggggtcgcagtatgacctggcttgtgggcaacaagctggtgaccataacaacc
agcggaggggtccgaacacaagcactgctaggcctggacatggctgaacgtctgggagga
ggaggggaaatgaccaggtcagatccatctctacacacccgaataaccaaagaggctccg
gccaaactggagtcacagtcaagccagcagcacaacagagccacacgcatacgggtccgc
tccatctcaggtggccacgctctacgcgccggtcctgctcagagcctcagtcctctcgtg
tccccttctgagggcgagttagccgctcctctctctccctcgaccggtcccacccttgat
ggcctgggtcctccctcctccatctctgtggccccatcgacccccccgcctctcaaagac
aaccccagtctggctgattttgtccccatactaacacagggctgggcagagattttcatc
cggagaccatcaggtaacacaagttggctcatgtgtctggagaacccacccagccccttc
tcctctgagctcggcaacatgccactgcaggagctctctactgtcctgatggcgatggag
ggagtgaaggagcctcctgcccagacaaccagcgctcccgctagcaccgctgctcccgcg
ccggcgcccgtctcagagcccctgacccaaacacacagcggcgtcgcagggaaggcaaac
ctgatccagcgctccaacactgttggtggctttctgtggtctgtgggtctgggctctgcc
ccctcaggccctccagccccgggcaggttgcacaggagcatttcctgggcagaatctgtg
gtggtgctggaggaaggctcaggggtcgctgcagcacacagcccgtctgattggctggag
agtgaggagtttgagccaatgtcctctgatcccatcttcatgtctgctgacaagttcacc
aagaccccgcctcctggaacactcagcaggtcctcctccacctccagtcaagatgatgag
aagtcgactctggaggaagtaagtgagggagcgattcccatcgatcagcccaccatggga
ccttctacaccaggcagccaggggcccgagcttcccttccagagtcattctccatcccag
ggtcacggacttaacaagtccagctcctctccggagctccagacgttacctgaagccttc
accaaggctgctctggagtccgagacggtgctggtagacacattgctacccagagcgccc
tcagatggcaagcctcagcagcagcaacctcactttgagaaagataaggtggaggtaagt
gcgggaggggacgttaatgggctgggaggccagagtcatggcgccgaaggccctgctgta
gcatcatctcagattggaggggcaaggatgaggctggagtttccaacggcggtggcacaa
cctggacccatctcccccggcggaggccaccggccccggggtcacaccatctcagtatcg
gccccctcctccagaagggagaggaggacagacagagacttgtaccacagtcggccagga
cccagcaacactgagaagatttctggactgagtcccagctttgtcttcctccagctgtac
cactctcctttctttgggaatgaggccaacaagccactgctgctgcctaaaactcaggtg
atcgaccgagctgtgaaggttctggaccagatgcctccttatgacacccataagatcgga
gtggtgtttgtaggagctggtcaggttaacaacgaagtctccatcctatcaaacgagtac
ggttcgaaccgctacgctgccttcctaacaggcctgggcaaactaatccatctgaaggac
tgtgaccccgaccagatcttccttggaggcctcgaccagtacggagacgacggagagttc
acctactgctggcatgacgacatcatgcaggcgatcttccacattgccacactgatgcca
aacagggagagcgacaagggctgctgcaacaaaaagcgtcacattggcaacgattttgtc
atggttgtgtacaatgactctggagaggactacaaacttggcacaattaagggccagttt
aactttgtagaggtcattataaaaccactggatttcgaatgtaacctggtcaccctccag
tgccgcaaagaccttgagggcttagtcgacacaacagtggcaaaaatcgtttcagaccgc
aaccttccactcttagtcagacagatggctctgcatgcgaatatggcctctttggtgcac
cagtacagagcaaacccttcagatgcttatgcctcgaagtggctggcgagattacgacac
attaagaggattaggaccagggcacaagaagacattcagtctcgctcgactcccggcatc
tcgctgacccaaggacacactcagcagaacaagtcgtttcagcagagcaatcaagcacca
aaccctgaaacctcggggcagagaaagagacttgtatcaacagtggacgatttcaccgat
tttgtttaa
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