KEGG   Hymenobacter swuensis: Hsw_0324
Entry
Hsw_0324          CDS       T03055                                 
Name
(GenBank) putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase
  KO
K01798  Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]
Organism
hsw  Hymenobacter swuensis
Pathway
hsw00300  Lysine biosynthesis
hsw00470  D-Amino acid metabolism
hsw00550  Peptidoglycan biosynthesis
hsw01100  Metabolic pathways
hsw01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:hsw00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    Hsw_0324
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    Hsw_0324
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    Hsw_0324
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    Hsw_0324
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:hsw01011]
    Hsw_0324
Enzymes [BR:hsw01000]
 5. Isomerases
  5.1  Racemases and epimerases
   5.1.1  Acting on amino acids and derivatives
    5.1.1.1  alanine racemase
     Hsw_0324
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     Hsw_0324
Peptidoglycan biosynthesis and degradation proteins [BR:hsw01011]
 Precursor biosynthesis
  Amino acid ligase
   Hsw_0324
  Racemase
   Hsw_0324
SSDB
Motif
Pfam: Ala_racemase_N Ala_racemase_C Mur_ligase_M Mur_ligase Mur_ligase_C
Other DBs
NCBI-ProteinID: AHJ95919
UniProt: W8ES20
LinkDB
Position
363257..365758
AA seq 833 aa
MLQFSDLPALTGGTLLQLPATPAAIQRLLLDSRRVQTPADSLFLALRGPQHDGHRYLPEL
YRAGVRQFLVQDDVPLADFPEAGFLRVPDTLAALQALAAHHRRRFPIPVFGITGSNGKTI
VKEWLAQLLSPDELICKSPRSYNSQVGVPLSVWELTASHTLGIFEAGISEPGEMARLVRI
IQPTLGIFTNLGTAHDAGFASPAEKVTEKMRLFEQVDTLFYCADHELIHAAARRQLSPAR
TTRVAWTRQRARFDAQEADLLITMQEAAADRAVVRVERARPRPQEHTFTLPFADEPSVEN
ALHGLAVLLWRQVPPTEIQQRLDRLQPVAMRLEMKQALHDCYVLDDTYNNDLAGLRLALD
ALARQARRGRRTLILSDVLESGLAGAELYARVAALLPAHGVERLIGIGPDISRHHAAFAG
LQAEFYPDTAAFLAAFQPEQFRQELILVKGARRYGFERIVAAFQQKIHGTVLEVNLDALV
HNLNFYRRRLQPGVKLMVMVKAFAYGSGSAEVANLLQFHRADYLAVAYADEGVDLRQSGI
SLPLMVMNPAPDAFQKLRQYHLEPEIYSFERLHDYLAAAREAAMPAIHLKLDTGMRRLGF
AEEDLPELCRLLHENAAHLRVASALTHLAGADEEQHNSFSREQLAAFARMTPQLEAALGY
PILQHALNSAGIVRFPEDQHSLVRLGIGLYGVEASGQEPDALRSVSTLRTTISQIKTLPA
GQTVGYGRRGQATDHERRIATLAIGYADGYDRRFGNGAGEVLIRGQRAPIVGNVCMDMCM
ADVTHIADAQAGDAAVVFGENLPLTELAARIGTIPYELLTNVSERVKRVFVAE
NT seq 2502 nt   +upstreamnt  +downstreamnt
atgctccagttctccgacctgcccgcgcttaccggcggcaccctgctccaacttcccgcc
accccggcagccattcagcggctgctgctggatagccgccgcgtgcaaacccccgccgac
agcctgttcctggccctgcgcggcccccagcacgacggccaccgctacctgcccgagttg
taccgggccggcgtgcgccagtttttggtgcaggacgacgtgccgctggccgactttcct
gaggccggtttcttacgggtgcccgataccctggcagccctgcaggcgctggcggcccac
caccgccgccgcttccccatcccggtgttcggcattaccggctccaacggcaaaaccatc
gtgaaggagtggctggcccaactgctgagccccgacgagctgatctgtaagagtccgcgc
tcctacaactcccaggtgggcgtgcccctgagcgtgtgggagcttaccgccagccacacg
ctgggcatcttcgaggccggcatttccgagcccggcgagatggcgcggctggttcgcatc
atccagcccacgctgggcatcttcaccaatctgggtacggcccacgatgccggtttcgcc
tcccccgccgaaaaggtgacggagaagatgcgcctgtttgagcaggtggataccctgttc
tattgcgccgaccacgagctgattcacgccgccgcccgccgccagctcagccccgcccgc
accacccgcgtggcctggacgcgccagcgcgcccgcttcgacgcccaggaagccgacctg
ctcatcactatgcaggaagccgctgccgaccgggccgtggtgcgggtggagcgcgcccgg
ccccgcccccaggagcacaccttcacgctgcctttcgccgatgagccctccgtagaaaac
gccctccacggcctggcggtgctgctgtggcggcaggtgccccccaccgaaatccagcag
cgcctcgaccggctccagcccgtggccatgcgtctggagatgaagcaggctttgcacgac
tgctacgtcctcgacgatacctacaacaacgacttggccggcctgcgcctcgccctcgat
gccctggcccggcaagcccgccggggccgccgcaccctcattctctccgatgtgctcgaa
tcgggcttagccggggccgaactgtacgcgcgggtggcggctttgctgccggcccacggc
gtggagcgcctcatcggcatcggccccgatatcagtcggcaccacgcggcgtttgcgggc
ctgcaggctgaattctaccccgacacggccgcgtttctggccgctttccaacccgagcag
ttccgccaggagttgattctggtgaaaggggcccgccgctacggcttcgagcggattgtt
gccgccttccagcagaaaatccacggcacagtgctggaagtaaacctcgacgcgctggtg
cacaaccttaacttctaccgtcgccgcctgcagcccggcgtgaagctgatggtgatggtg
aaggcctttgcctacggcagcggctcggccgaagtcgccaacctgcttcagttccaccgc
gcagactacctggccgtggcctacgccgacgagggcgtggacctgcgccagagcggcatc
agcctgccgctgatggtgatgaacccggctcccgacgccttccagaagctgcgccagtac
cacctggaacccgaaatctactccttcgagcgcctgcacgactacctggccgccgcccgc
gaggccgccatgcccgccatccacctcaagctcgataccggcatgcgccgcctgggcttc
gccgaggaagacctgcccgagctgtgtcggctgctgcacgaaaacgccgcccacctgcgc
gtagccagcgccctcacccacttggccggagccgacgaggagcagcacaacagcttctcg
cgggagcagctggccgccttcgcccgcatgacgccccagctggaggcggccctgggctac
cccattctccagcacgccctcaactcggccggcattgtgcggtttccggaggaccagcac
agtctggtacgccttggcatcggcctctatggggtggaagccagtggccaggagcccgac
gcgctgcggtctgtgagcaccctgcgtaccaccatttcccagatcaaaaccctgccggcg
ggccagacggtgggctacggccgccgcggccaagccaccgaccacgagcggcgcattgcc
accctggccatcggctatgccgacggctacgaccggcgcttcggcaacggggcgggcgag
gtgcttatccgtgggcaacgggcgcccatcgtaggcaacgtgtgcatggacatgtgcatg
gccgacgtgactcacattgccgacgctcaagccggcgacgcggccgtggtattcggcgaa
aacctgcccctcacggagctggccgcgcgcatcggcaccattccgtatgagttgctgacc
aacgtaagcgagcgggtgaagcgagtgttcgtagcagaatag

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