KEGG   Hydrogenobacter thermophilus: HTH_1800
Entry
HTH_1800          CDS       T01167                                 
Symbol
ddlA
Name
(GenBank) D-alanine:D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
hth  Hydrogenobacter thermophilus
Pathway
hth00470  D-Amino acid metabolism
hth00550  Peptidoglycan biosynthesis
hth01100  Metabolic pathways
hth01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:hth00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    HTH_1800 (ddlA)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    HTH_1800 (ddlA)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    HTH_1800 (ddlA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:hth01011]
    HTH_1800 (ddlA)
Enzymes [BR:hth01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     HTH_1800 (ddlA)
Peptidoglycan biosynthesis and degradation proteins [BR:hth01011]
 Precursor biosynthesis
  Amino acid ligase
   HTH_1800 (ddlA)
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp_4 ATP-grasp_3 RimK CPSase_L_D2 GARS_A ATP-grasp
Other DBs
NCBI-ProteinID: BAI70244
UniProt: D3DK92
LinkDB
Position
1636237..1637103
AA seq 288 aa
MRVVVLMGGRSEEREISLKTGEAVLRAIRELGHEAIPLDLEENLCQKLLEIKPDKVFIAL
HGTYGEDGRVQGLLDILGIPYTGSGVLGSCLAMDKDITKKILTFHRIPVPAGICVRRGET
FEWHSFPAVVKPADQGSSVGLFLVKDHDELENAVREVLSISHKVLIEEYIIGRDITVGIL
KGEALPPVEIKPKKGIYDYESKYTKGMSDYVFLEDEKLIKKLQDIALMVHKYLELKDISR
VDFRLSEDGVAYVLEANTIPGMTELSLFPMMCKKKGIEFKEMIHMLLS
NT seq 867 nt   +upstreamnt  +downstreamnt
ttgagagttgtagtactcatggggggcaggtctgaggagagagagatatctttgaaaact
ggagaggctgtgttaagagccatcagggagctggggcacgaagcaataccacttgacttg
gaggaaaacctctgccagaaactccttgagataaagccagacaaggtctttatagcactt
cacggcacttacggcgaagatggaagagtgcaggggcttctggacatcctgggcattccg
tatacaggctctggagtgctgggtagctgtcttgccatggataaggacataaccaaaaag
atactgactttccaccgcatacctgtgcctgcgggtatatgtgtgcgcagaggggagact
tttgaatggcacagctttcccgcggtagtaaaacctgctgaccagggctcaagcgtaggg
ctttttctggtaaaagaccatgatgagcttgaaaatgcagtaagggaagtgcttagtatc
tctcacaaggtgctgatagaagagtacataatagggagggatataacggtgggaatacta
aagggcgaggctcttcctcccgtagagataaaaccaaagaagggcatctatgactacgag
agcaagtacaccaaaggcatgtccgattatgtctttttagaggatgaaaagctaatcaag
aagcttcaggacatagctttaatggtacacaaatatttagaacttaaggacatttcacgc
gtagacttcagattgtctgaggatggtgtagcgtatgttttggaagccaacaccatacct
ggaatgacagaactcagtctttttcccatgatgtgtaaaaagaaaggtattgaatttaaa
gagatgatacatatgttattatcttag

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