Hydrogenophilus thermoluteolus: HPTL_1344
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Entry
HPTL_1344 CDS
T05630
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
htl
Hydrogenophilus thermoluteolus
Pathway
htl00230
Purine metabolism
htl01100
Metabolic pathways
htl01110
Biosynthesis of secondary metabolites
Module
htl_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
htl00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
HPTL_1344 (purL)
Enzymes [BR:
htl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
HPTL_1344 (purL)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Tegument_dsDNA
Motif
Other DBs
NCBI-ProteinID:
BBD77608
UniProt:
A0A2Z6DZ49
LinkDB
All DBs
Position
complement(1420651..1424586)
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AA seq
1311 aa
AA seq
DB search
MTIWHFLGSRTWSAAREASASARVSRALGTRVTLTAYAWYWLEMAPDHGDETSLDARLAQ
ILQGERQKTPRWSEGFLVAPRLGTISPWSSKATEILHQCGLTAVKRIEHGTAIRVAEWGS
LTGEQQAGVAALLHDRMTQSILKDPETGEALFAHYSPKPLATAPVMSEGRAAIERANREW
GLALSEDEIDYLFAAFTELGRDPTDVELTMFAQANSEHCRHKIFNAEWVIDGRPMAQSLF
AMIRDTHAAHPEGTVVAYADNAAVFTGRTVARWFPDEDGVWRAHQTTTHFLGKVETHNHP
TAIAPYPGAATGAGGEIRDEGATGRGASPKMGLAGFTVSNLHLPDFVQPWEKPYGKPDRI
ASPLEIMIEGPLGAAAFNNEFGRPNLCGYFRTFEREVQGEVRGYHKPIMIAGGLGAIAAE
QSHKVGFAPGTLLVQLGGPGMLIGLGGGAASSMATGANDAELDFASVQRDNPEMQRRCQE
VIDRCWALGAENPILSIHDVGAGGLSNALPELVDGAGLGATIELREVPIEEPGMSPREIW
CNEAQERYVLAIDPTQLERFAAICARERCPFAVVGEATEDGMLRVHDRLFGNDPVALPME
VLLGKPPRMKRVVASRTIFLPPFDLTAIDVRDAVMRVLAHPAVASKKFLITIGDRTVGGL
TARDQLVGRWQVPVADVAVTAADFVGFAGEAMAMGERTPVAINDPAASVRLAIAEAVTNL
GAADVRGPLTTVKLSANWMAAAGHRGEDANLYRAVQAARDFCVASGLAIPVGKDSLSMKT
VWQDPETGEAKAVIAPVSLICTAFAAVADVRRTLTPVLDRDTPETELLLIDLDGARNRLG
GSIFAQVFDSQGETPPDCAPETLVAFWEALQALKANDLILAYHDRSDGGLLATAAEMMFA
SGVGVTLQLDTLAYDRATHDIDYTKRNDTVVGRRNDAALAALFSEAPGALVQIRRSDRDV
VLAILQKYRLTFHFVGTLNTYDELRIWLEGSLLFHEKRTVLWQRWSEVSRRIARLRDDET
CAESEFEALGDAQDPGLHCVLTFDPDEDPAAPFVATGVRPRVAILREQGVNSHREMAAAF
DAAGFEAVDVTMSDLIAGRRHLSDFVGLAACGGFSYGDVLGAGRGWATAILFNDALKTQF
SEFFARPDTFALGVCNGCQMMAHLAPIIPGAEHWPKFVANRSERFEARFAMVEVLPSPSI
LFTDMAGARLPIVVSHGEGRAHWEDPERQHQALATIRYIDHYGRATERYPFNPNGSPGGL
NGFTTADGRFTILMPHPERAFRTVQWSWAPEGLGEKSPWYRLFANARRWVG
NT seq
3936 nt
NT seq
+upstream
nt +downstream
nt
atgacgatttggcatttccttggttcccgaacctggtctgcggcgcgcgaagcgagcgcg
agtgcgcgcgtgtcgcgtgcgttgggcacccgtgtgacgctgaccgcgtacgcgtggtat
tggctcgaaatggcgccggaccacggggatgagacgtcgttggatgcgcgtttggcccaa
attttgcagggagaacggcaaaaaacgcctcgttggagcgaagggttcctggtggcgccg
cggctggggacgatctcaccgtggtcgtcgaaggccaccgaaatcctgcaccagtgtggg
ttgactgcggtgaagcgcatcgaacacggtacggcgattcgtgttgccgaatggggcagc
ttgaccggcgagcaacaagccggggtcgctgccttgcttcacgatcggatgacgcaatcg
atcctgaaggaccccgagacaggagaggcgctctttgcccattattccccgaaaccgctc
gccaccgcgccggtgatgagcgaggggcgtgccgcgatcgaacgggcgaaccgcgaatgg
gggcttgccctgtccgaagacgagatcgattacctcttcgccgctttcaccgaactgggg
cgcgatcccaccgacgtcgaactgacgatgttcgcgcaagccaattcggaacattgccgt
cacaagattttcaatgccgagtgggtaatcgacggtcggccgatggcgcagtcgctcttt
gcgatgatccgggatacccatgcggcgcatccggagggcacggtggtcgcgtacgccgac
aacgcggcggtcttcaccggacggaccgtggcgcggtggtttccggatgaggacggggtc
tggcgcgcgcaccaaaccactacccattttttgggcaaagtcgaaacccacaaccacccc
actgcgattgctccctatccgggtgccgcgactggggcgggcggcgagattcgcgacgaa
ggggcaaccgggcggggcgcttccccgaaaatggggttggctgggtttaccgtctcgaat
ctgcacttgcccgatttcgtgcagccgtgggaaaaaccctacggcaagcccgatcggatc
gcgtcgccgctcgagatcatgatcgaagggccgcttggcgccgcggcgttcaacaacgag
ttcgggcgacccaatctctgtggctatttccgcacgttcgaacgtgaagtccagggcgag
gtgcgcggctaccacaaaccgatcatgatcgcaggcggcttgggggcgatcgcggcggaa
cagagccacaaagtcggctttgcgcccggaacgctcctggtgcagttgggtgggccgggg
atgctcatcggtctgggtggcggtgcggcttcgtcgatggctacgggcgcgaacgacgcg
gaactcgatttcgcgtcggtgcaacgtgacaacccggaaatgcagcgccgttgtcaggag
gtgatcgaccgttgttgggccttgggggcagagaacccgattctctcgatccacgacgtg
ggtgccgggggcctttcgaacgcccttcccgaactggtcgatggggcgggactgggtgct
acgatcgagttgcgcgaggtgcccatcgaagagcccgggatgagcccgcgtgaaatctgg
tgtaacgaggcgcaagagcggtacgtgctggcgatcgatccgacgcaactggagcggttc
gctgcgatttgtgcccgggaacggtgcccgttcgcggtcgtcggcgaggcgaccgaagat
gggatgctccgcgtgcacgatcgcctcttcggcaacgatcccgtagcgctcccgatggaa
gtgctgctgggcaaaccaccgcgcatgaagcgggtggtagccagccgaacgatcttcttg
ccgccgttcgatctcactgcgatcgacgtgcgcgacgcggtgatgcgcgtcctggcgcat
ccggcagtggcaagcaagaagttcctgatcacgatcggtgaccgcaccgtcggtggcttg
accgcgcgtgaccaattggtggggcgctggcaggtgccagttgccgacgtcgcagtgacc
gccgccgatttcgtcgggttcgccggtgaggcgatggcaatgggcgaacgcacgccggtg
gcgatcaacgaccccgcggcgtcggttcgcctggcgattgccgaagcggtcaccaacctg
ggggcagcggatgtgcgcggaccgctcaccacggtgaaactctccgcgaactggatggcc
gcagctgggcaccgtggcgaagacgcgaacctctaccgtgccgtgcaggcggcgcgtgat
ttctgcgtcgcgtcggggcttgcgatccccgtgggcaaagattcgttgtcgatgaagacg
gtctggcaagaccccgaaacgggggaagccaaagcggtgatcgcacccgtttccctgatc
tgtaccgcttttgccgcggtcgccgacgttcgacggactctcaccccggtgctcgatcgc
gacacccccgaaaccgaactgctgctgatcgacttggacggcgcacgcaaccgcttgggt
ggctcgatttttgcgcaggtgttcgattcgcaaggagaaaccccccccgattgcgcgccg
gaaaccctcgtggcgttctgggaagcgctgcaggcgctcaaagccaacgatctgatcctg
gcttaccacgaccgttccgatggggggctgctcgcgaccgcggccgagatgatgttcgcc
tcaggggtgggggtgacgctgcagctcgacaccctggcgtatgaccgcgccacgcacgac
atcgactacaccaagcgcaacgacacggtggttgggcggcgcaacgacgcggcgcttgcc
gcgctatttagcgaagcgccgggtgcactcgtgcagattcggcgcagcgatcgcgatgtg
gtgctcgcgattttgcagaaatatcggctgacgttccatttcgttggaaccctcaatacc
tacgacgaattgcggatttggctggaaggttcgctcctctttcacgagaagcggaccgtg
ctgtggcagcgttggagcgaagtgagccgacgcatcgcgcgcctgcgtgacgatgaaacc
tgcgccgaatccgagttcgaggcgttgggcgatgcccaagatccggggctccattgcgtg
ctcacgttcgaccccgacgaagaccctgccgctccgttcgtcgccaccggcgtgcgcccg
cgggttgcgatcctgcgcgaacagggggtaaacagccaccgtgagatggccgctgcattc
gacgcggcaggattcgaggcggttgacgtgacgatgagtgacctcattgcggggcggcgc
catctcagcgatttcgtagggcttgccgcgtgtggcgggttttcatacggcgacgtgctg
ggcgccgggcgtggctgggctacggcaatcctcttcaacgacgcgctgaaaacgcagttc
agcgaattttttgcccgtccggacacctttgcgctcggggtctgcaacggctgtcagatg
atggcacacctggcgccgatcatcccgggagcggaacactggccgaagttcgtcgccaac
cgttccgaacggttcgaagcgcgtttcgcgatggtcgaggtattgcccagcccctcgatc
ctctttaccgatatggccggggcgcggttaccgatcgtcgtctcgcacggagaagggcgt
gcgcattgggaggatccggagcggcaacaccaagcgttggcaacgattcgctacatcgac
cattatggccgcgccaccgagcgctacccgttcaacccgaacggctcgccgggcgggctc
aatggcttcacgacagcggacggacggttcacgattttgatgccgcacccggagcgggcc
ttccgaacggtgcagtggagttgggcgccagaggggctcggcgagaaaagcccctggtat
cggctctttgccaacgcgcgtcgctgggtaggctag
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